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F8ATC0 (F8ATC0_BIFLN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
ORF Names:BLNIAS_02418 EMBL AEI98196.1
OrganismBifidobacterium longum subsp. longum KACC 91563 [Complete proteome] EMBL AEI98196.1
Taxonomic identifier1035817 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain172 – 391220ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding204 – 26663ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3451Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3581Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3581Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3601Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F8ATC0 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 663BEE32F106B58C

FASTA39542,355
        10         20         30         40         50         60 
MAKKRVVVLY GGRADEHSIS CISTAGVLGA MDTERFEPIP VGITKDGKWV INGEDPRGWN 

        70         80         90        100        110        120 
LDGGELPTVK ITPESRPVML DPSRGQDGFF IGEPSHINSA DSGFGTSFVS MSDPEMHHVL 

       130        140        150        160        170        180 
TSLGHVDAVL PVLHGPYGED GTVQGLLEMM GVPYVGCGVF ASAACMDKHY TKVVLDAAGI 

       190        200        210        220        230        240 
PTAPGVTVDA RNFTAADVLA EIEDAGLTYP LFVKPSRAGS SFGVTKVEKA DDRETQQDRL 

       250        260        270        280        290        300 
AAAIATAGEH DWKVLVEQGI DGREIECAVL CPKAGDEPEA SWPGEIVLDH QNDDQFYDFD 

       310        320        330        340        350        360 
SKYMDASASH VEVPANLPVS VLEDVRDVAR RAFKAVDGAG LSRVDTFVTP DGTVMVNEIN 

       370        380        390 
TMPGFTPISM YPKAWDATGV SYTELITRLI EGVLR 

« Hide

References

[1]"Complete Genome Sequence of Bifidobacterium longum subsp. longum KACC 91563."
Ham J.S., Lee T., Byun M.J., Lee K.T., Kim M.K., Han G.S., Jeong S.G., Oh M.H., Kim D.H., Kim H.
J. Bacteriol. 193:5044-5044(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: KACC 91563 EMBL AEI98196.1.
[2]Ham J.-S., Kim M.-K., Han G.-S., Jeong S.-G., Oh M.-H., Ki D.-H., Lee K.-T., Lee T., Byun M.-J., Kim H.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: KACC 91563 EMBL AEI98196.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002794 Genomic DNA. Translation: AEI98196.1.
RefSeqYP_005587947.1. NC_017221.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEI98196; AEI98196; BLNIAS_02418.
GeneID12165226.
KEGGblk:BLNIAS_02418.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycBLON1035817:GL98-1674-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 2 hits.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 2 hits.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8ATC0_BIFLN
AccessionPrimary (citable) accession number: F8ATC0
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)