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Protein

Beta-galactosidase

Gene

lacA1

Organism
Bifidobacterium longum subsp. longum KACC 91563
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei121 – 1211SubstrateUniRule annotation
Active sitei160 – 1601Proton donorUniRule annotation
Active sitei318 – 3181NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

BioCyciBLON1035817:GL98-1460-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Gene namesi
Name:lacA1Imported
ORF Names:BLNIAS_02129Imported
OrganismiBifidobacterium longum subsp. longum KACC 91563Imported
Taxonomic identifieri1035817 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000008938 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 42 family.UniRule annotation

Phylogenomic databases

KOiK12308.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

F8ASA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERKEFKWPQ PLAGNKPRIW YGGDYNPDQW PEEVWDEDVA LMQQAGVNLV
60 70 80 90 100
SVAIFSWAKL EPEEGVYDFD WLDRVIDKLG KAGIAVDLAS GTASPPMWMT
110 120 130 140 150
QAHPEILWVD YRGDVCQPGA RQHWRATSPV FLDYALNLCR KMAEHYKDNP
160 170 180 190 200
YVVSWHVSNE YGCHNRFDYS EDAERAFQKW CEKKYGTIDA VNDAWGTAFW
210 220 230 240 250
AQRMNNFSEI IPPRFIGDGN FMNPGKLLDW KRFSSDALLD FYKAERDALL
260 270 280 290 300
EIAPKPQTTN FMVSAGGTGI DYDKWGYDVD FVSNDHYFTP GEAHFDELAY
310 320 330 340 350
SASLCDGIAR KNPWFLMEHS SSAVNWRPIN YRVEPGELVR DSLAHLAMGS
360 370 380 390 400
DAICYFQWRQ SKAGAEKWHS SMVPHAGPDS QIFRDVCELG ADLNKLADEG
410 420 430 440 450
LLSTKLVKSK VAVVFDYESQ WATEHTATPT QEVRHWTEPL AWFRALADNG
460 470 480 490 500
LTADVVPVRG SWDEYEAVVL PSLTILSEET TRRVREYVAN GGKLFVTYYT
510 520 530 540 550
GLVDDKDHVW LGGYPGSIRD VVGVRVEEFA PMGNDFPGAM DHLDLDNGTV
560 570 580 590 600
AHDFADVITS VADTAHVVAS FKADKWTGFD GAPAITVNDF GDGKAAYVGA
610 620 630 640 650
RLGREGLAKS LPVLLEELGI ETSAEDDRGE VLRVERADET GENHFVFLFN
660 670 680 690
RTHDVAVVDV EGEPLVASLA QVNESEHTAA IQPNGVLVVK L
Length:691
Mass (Da):77,462
Last modified:September 21, 2011 - v1
Checksum:i2D33CEDF9ACB5365
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002794 Genomic DNA. Translation: AEI97988.1.
RefSeqiWP_014485807.1. NC_017221.1.
YP_005587739.1. NC_017221.1.

Genome annotation databases

EnsemblBacteriaiAEI97988; AEI97988; BLNIAS_02129.
KEGGiblk:BLNIAS_02129.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002794 Genomic DNA. Translation: AEI97988.1.
RefSeqiWP_014485807.1. NC_017221.1.
YP_005587739.1. NC_017221.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEI97988; AEI97988; BLNIAS_02129.
KEGGiblk:BLNIAS_02129.

Phylogenomic databases

KOiK12308.

Enzyme and pathway databases

BioCyciBLON1035817:GL98-1460-MONOMER.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete Genome Sequence of Bifidobacterium longum subsp. longum KACC 91563."
    Ham J.S., Lee T., Byun M.J., Lee K.T., Kim M.K., Han G.S., Jeong S.G., Oh M.H., Kim D.H., Kim H.
    J. Bacteriol. 193:5044-5044(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KACC 91563Imported.

Entry informationi

Entry nameiF8ASA8_BIFLN
AccessioniPrimary (citable) accession number: F8ASA8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 24, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.