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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pyrococcus yayanosii (strain CH1 / JCM 16557)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PYCH_03070Imported
OrganismiPyrococcus yayanosii (strain CH1 / JCM 16557)Imported
Taxonomic identifieri529709 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000008386 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi529709.PYCH_03070.

Structurei

3D structure databases

ProteinModelPortaliF8AIQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 90Arg_tRNA_synt_NInterPro annotationAdd BLAST88
Domaini507 – 629DALR_1InterPro annotationAdd BLAST123

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili221 – 255Sequence analysisAdd BLAST35

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi128 – 138"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiarCOG00487. Archaea.
COG0018. LUCA.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG093Z013U.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

F8AIQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLERLKGEVG KAVADVVREL APGWEGRIEF ADTPSPEMGD FGTAVAFQLA
60 70 80 90 100
RVLRKAPKLI AEELAERLRD RLPEGIREVR AVNGYINFFI DYGAFARALI
110 120 130 140 150
REILTKGDRY GEGIVGRGRK VIVEHTSVNP TKPLHMGHAR NAVLGDTMAR
160 170 180 190 200
IMRFLGYEVE VQNYIDDLGV QFAQVYWGYL NLREEFERIM AELKEKGLKK
210 220 230 240 250
NPIDHALGLL YVEVNRRLEE NPELEGQIRA LMKQLEEGNE EGRKLAEEVV
260 270 280 290 300
RAQLETTRRL GIEYDLLSWE SDIMRSGIFE EAMEMLQGNE NFYTPEEGKY
310 320 330 340 350
KGAFVMDLRK LFPDMKNPFL VLVRSDGTAT YTGKDIAYHL WKFGKVKADM
360 370 380 390 400
LYKPWDGKTW TTAPDGKEMP GRFGRADVVI NVIGAEQRHP QMAIKYALQL
410 420 430 440 450
LGFEESAENF HHLAYEHVVR PEGKFSGRKG TWVGFTVDEV LDEAVKRARE
460 470 480 490 500
LVEEKNPNLS EEEKWEIAEK VGVGAIRFNL LKYSPDKVIT FRWEDALNFE
510 520 530 540 550
GESAPYVQYA HARCASILRK AEEGGLNIEW ESLLQRADFS KLTEKERELL
560 570 580 590 600
MLLAKFPEVV ETAGKDVRPH LLAWYANELA SLFNKFYMDH PVLRAEKGVR
610 620
EARLLLVMAV KQVLRNVLWL MGIEAPERM
Length:629
Mass (Da):72,073
Last modified:September 21, 2011 - v1
Checksum:iD109455164D84D3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002779 Genomic DNA. Translation: AEH24004.1.
RefSeqiWP_013905062.1. NC_015680.1.

Genome annotation databases

EnsemblBacteriaiAEH24004; AEH24004; PYCH_03070.
GeneIDi10836884.
KEGGipya:PYCH_03070.

Similar proteinsi

Entry informationi

Entry nameiF8AIQ8_PYRYC
AccessioniPrimary (citable) accession number: F8AIQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 22, 2017
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported