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Protein

dTDP-4-dehydrorhamnose reductase

Gene

Thein_0725

Organism
Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.UniRule annotation

Catalytic activityi

dTDP-beta-L-rhamnose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH.UniRule annotation

Pathwayi: dTDP-L-rhamnose biosynthesis

This protein is involved in the pathway dTDP-L-rhamnose biosynthesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway dTDP-L-rhamnose biosynthesis and in Carbohydrate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADPUniRule annotation

Enzyme and pathway databases

BioCyciTIND667014:GI6G-736-MONOMER.
UniPathwayiUPA00124.

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-4-dehydrorhamnose reductaseUniRule annotation (EC:1.1.1.133UniRule annotation)
Gene namesi
Ordered Locus Names:Thein_0725Imported
OrganismiThermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)Imported
Taxonomic identifieri667014 [NCBI]
Taxonomic lineageiBacteriaThermodesulfobacteriaThermodesulfobacterialesThermodesulfobacteriaceaeThermodesulfatator
Proteomesi
  • UP000006793 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi667014.Thein_0725.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 276RmlD_sub_bindInterPro annotationAdd BLAST276

Sequence similaritiesi

Belongs to the dTDP-4-dehydrorhamnose reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DBZ. Bacteria.
COG1091. LUCA.
KOiK00067.
OMAiYHYSNEG.
OrthoDBiPOG091H07IL.

Family and domain databases

InterProiView protein in InterPro
IPR005913. dTDP_dehydrorham_reduct.
IPR016040. NAD(P)-bd_dom.
IPR029903. RmlD-like-bd.
PANTHERiPTHR10491. PTHR10491. 1 hit.
PfamiView protein in Pfam
PF04321. RmlD_sub_bind. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01214. rmlD. 1 hit.

Sequencei

Sequence statusi: Complete.

F8AC50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLILGKRG QLGSTFGNVL REQSKYKCLF LSREECDIGN LTRVLEVFKE
60 70 80 90 100
FRPDVVINCA AYNLVDRAEE FPWEAMRVNF GGVCNLVYAC RTYNSFLVHY
110 120 130 140 150
STDYVFDGEK EGLYTEEDDT NPLNNYGKSK LYGENFIRDN LENYLIFRTS
160 170 180 190 200
WVYGEGKQNF LYKLMQWAEK QEYLRIACDE FSVPTSTRTI VEVTLKALDT
210 220 230 240 250
GLKGLYHLVN SGYASRYEWA KAFFKIKGIK KFIYPASQAD FDLPAKRPRF
260 270
SAMSNSRICK KLNIEIADWR EELVEWLGC
Length:279
Mass (Da):32,473
Last modified:September 21, 2011 - v1
Checksum:i3EB1DE312880E704
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002683 Genomic DNA. Translation: AEH44605.1.
RefSeqiWP_013907349.1. NC_015681.1.

Genome annotation databases

EnsemblBacteriaiAEH44605; AEH44605; Thein_0725.
KEGGitid:Thein_0725.
PATRICifig|667014.3.peg.751.

Similar proteinsi

Entry informationi

Entry nameiF8AC50_THEID
AccessioniPrimary (citable) accession number: F8AC50
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 27, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported