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Protein

dTDP-4-dehydrorhamnose reductase

Gene

Thein_0725

Organism
Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.UniRule annotation

Catalytic activityi

dTDP-beta-L-rhamnose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH.UniRule annotation

Pathwayi: dTDP-L-rhamnose biosynthesis

This protein is involved in the pathway dTDP-L-rhamnose biosynthesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway dTDP-L-rhamnose biosynthesis and in Carbohydrate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADPUniRule annotation

Enzyme and pathway databases

BioCyciTIND667014:G1GYJ-740-MONOMER
UniPathwayiUPA00124

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-4-dehydrorhamnose reductaseUniRule annotation (EC:1.1.1.133UniRule annotation)
Gene namesi
Ordered Locus Names:Thein_0725Imported
OrganismiThermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)Imported
Taxonomic identifieri667014 [NCBI]
Taxonomic lineageiBacteriaThermodesulfobacteriaThermodesulfobacterialesThermodesulfobacteriaceaeThermodesulfatator
Proteomesi
  • UP000006793 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi667014.Thein_0725

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 276RmlD_sub_bindInterPro annotationAdd BLAST276

Sequence similaritiesi

Belongs to the dTDP-4-dehydrorhamnose reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DBZ Bacteria
COG1091 LUCA
KOiK00067
OMAiYHYSNEG
OrthoDBiPOG091H07IL

Family and domain databases

InterProiView protein in InterPro
IPR005913 dTDP_dehydrorham_reduct
IPR036291 NAD(P)-bd_dom_sf
IPR029903 RmlD-like-bd
PANTHERiPTHR10491 PTHR10491, 1 hit
PfamiView protein in Pfam
PF04321 RmlD_sub_bind, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR01214 rmlD, 1 hit

Sequencei

Sequence statusi: Complete.

F8AC50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLILGKRG QLGSTFGNVL REQSKYKCLF LSREECDIGN LTRVLEVFKE
60 70 80 90 100
FRPDVVINCA AYNLVDRAEE FPWEAMRVNF GGVCNLVYAC RTYNSFLVHY
110 120 130 140 150
STDYVFDGEK EGLYTEEDDT NPLNNYGKSK LYGENFIRDN LENYLIFRTS
160 170 180 190 200
WVYGEGKQNF LYKLMQWAEK QEYLRIACDE FSVPTSTRTI VEVTLKALDT
210 220 230 240 250
GLKGLYHLVN SGYASRYEWA KAFFKIKGIK KFIYPASQAD FDLPAKRPRF
260 270
SAMSNSRICK KLNIEIADWR EELVEWLGC
Length:279
Mass (Da):32,473
Last modified:September 21, 2011 - v1
Checksum:i3EB1DE312880E704
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002683 Genomic DNA Translation: AEH44605.1
RefSeqiWP_013907349.1, NC_015681.1

Genome annotation databases

EnsemblBacteriaiAEH44605; AEH44605; Thein_0725
KEGGitid:Thein_0725
PATRICifig|667014.3.peg.751

Similar proteinsi

Entry informationi

Entry nameiF8AC50_THEID
AccessioniPrimary (citable) accession number: F8AC50
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 28, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported