F8A939 (F8A939_THEID) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP-Rule MF_00006
Short name=ASAL HAMAP-Rule MF_00006
EC=4.3.2.1 HAMAP-Rule MF_00006

Alternative name(s):
Arginosuccinase HAMAP-Rule MF_00006

Gene names

Name:	argH HAMAP-Rule MF_00006
Ordered Locus Names:	Thein_1300 EMBL AEH45167.1

Organism

Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812) [Complete proteome] [HAMAP] EMBL AEH45167.1

Taxonomic identifier

667014 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Thermodesulfobacteria › Thermodesulfobacteria › Thermodesulfobacteriales › Thermodesulfobacteriaceae › Thermodesulfatator › Thermodesulfatator indicus

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP-Rule MF_00006 SAAS SAAS009049
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP-Rule MF_00006 SAAS SAAS009049
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00006 SAAS SAAS009049.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP-Rule MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP-Rule MF_00006 SAAS SAAS009049
Cellular component	Cytoplasm HAMAP-Rule MF_00006 SAAS SAAS009049
Molecular function	Lyase HAMAP-Rule MF_00006 SAAS SAAS009049 EMBL AEH45167.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F8A939 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: E2099AC0919F05DC	FASTA	459	51,774
	10 20 30 40 50 60 MAQKPWGGRF SEETDKLVEE FTASVHYDKR LALYDIRGSI AHARMLGKTG IIPLEDAEKI 70 80 90 100 110 120 IAGLKEIEKD IKEGRFKWRK DLEDVHMNIE AALYEKIGPV AGKLHTARSR NDQVATDVRL 130 140 150 160 170 180 FLRDVIDETL SRLKDLRKAL VEKAKENLEV ILPGFTHLQH AQPVLLAHHL MAYYEMFTRD 190 200 210 220 230 240 AKRFAFVRQE TNVCPLGSAA LAGTPFPVDR EMVAQELGFA GITRNSMDAV SDRDFIVSFL 250 260 270 280 290 300 AAASLAFVHL SRLSEELILW ISQEFGFIDL PDKLCTGSSI MPQKKNPDVA ELIRGKSGRV 310 320 330 340 350 360 FGNLFTLLTV LKGLPMTYNR DLQEDKEPLF DTVDTLLAVL ALAKELIVGL KVNRERMRKA 370 380 390 400 410 420 CEEGHLTATD LADYLVTKGL PFREAHHVVG RLVAYCEEKG QKLWELPIEK LKEFSELIGE 430 440 450 DVYEWLTLEG SVSRRKVVGG TAPEQVEKAI YQAEKELEA

References

[1]

"The complete genome of Thermodesulfatator indicus DSM 15286." Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders L., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V. , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P., Eisen J.A. Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15286 / JCM 11887 / CIR29812.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002683 Genomic DNA. Translation: AEH45167.1.
RefSeq	YP_004626131.1. NC_015681.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEH45167; AEH45167; Thein_1300.
GeneID	10841557.
KEGG	tid:Thein_1300.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01755.
Enzyme and pathway databases
BioCyc	TIND667014:GI6G-1333-MONOMER.
UniPathway	UPA00068; UER00114.
Family and domain databases
Gene3D	1.10.275.10. 1 hit.
HAMAP	MF_00006. Arg_succ_lyase.
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR024083. Fumarase/histidase_N. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR022761. Fumarate_lyase_N. IPR008948. L-Aspartase-like. [Graphical view]
PANTHER	PTHR11444:SF3. PTHR11444:SF3. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. argH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F8A939_THEID

Accession

Primary (citable) accession number: F8A939

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	May 29, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)