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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cellulomonas gilvus (strain ATCC 13127 / NRRL B-14078) (Cellvibrio gilvus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei166UniRule annotation1
Active sitei564UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Celgi_1195Imported
OrganismiCellulomonas gilvus (strain ATCC 13127 / NRRL B-14078) (Cellvibrio gilvus)Imported
Taxonomic identifieri593907 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesCellulomonadaceaeCellulomonas
Proteomesi
  • UP000000485 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi593907.Celgi_1195.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 2 hits.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.

Sequencei

Sequence statusi: Complete.

F8A1Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYVERVTAP LLPRDVPRGL ASHEVPEPLR NDVRVLGEFL GRVLRESVGD
60 70 80 90 100
DLLADVERLR ELAIKAHDDP ESDALARAEE LVAGFTLTRA EQVARAFTCY
110 120 130 140 150
FHLANTAEEY HRVRVLRERE AHADPHALTP DDSLPAALAQ LSDEVGPDEA
160 170 180 190 200
RRRLQEAEFR PVLTAHPTEA RRRAVSRSIR RIAELVAERD VRSVGGMSLA
210 220 230 240 250
ENDRRLLAEI DTLWRTAPLR QAKPSVLDEV RTVLSVFEST LADVLPAVYR
260 270 280 290 300
RLDDWILDGE AGTTPPVVRP FARLGSWIGG DRDGNPNVTA EVTRAAAQLA
310 320 330 340 350
SEQVLVALEQ SARRTAAGLT LDATGTPPSS ELNALWQRQR SLSEEIASRV
360 370 380 390 400
AADSPNEPHR RELLFVVERL GATRGRNADL AYGSSAELEA DLLVVQRSLV
410 420 430 440 450
AGGATRQAFG DLQRLLWQVQ TFGFHLAELE LRQHSQVHEG ALADIEAHGI
460 470 480 490 500
DGELEPRTVE VLDTFRTIGT IQKRFGPEAA RRYIVSFTQS AEHLAAVYRL
510 520 530 540 550
AELAYGGPEN VPVIDAIPLF ETFADLEASV DILQGALELP QVRKRLAENG
560 570 580 590 600
RRVEVMLGYS DSSKDVGPVS ATLALDDAQR RITAWAREND IVLTLFHGRG
610 620 630 640 650
GALGRGGGPA NRAVLAQPPG SVDGRFKLTE QGEVIFARYG DAHIAARHIE
660 670 680 690 700
QVVAATLLAG APSVEKRNAD AAERFAGLAA RLDEASRTHF HALVRADGFP
710 720 730 740 750
QWFSAVTPLE EIGLLPIGSR PARRGLSVSS LDDLRAIPWV FSWSQARINL
760 770 780 790 800
AGWYGLGTAL EQVDDLAELR AAYAQWPLFG TMIDNVEMSL AKTDERIAAR
810 820 830 840 850
YLELGDRDDL ARAVLDEMAR TRRWVLAITE SDAMLSRRRI LGRAVQLRSP
860 870 880 890
YVDALSLLQL RALRGLRTGD AVEHADDLRR LLLLTVNGVA AGVQNTG
Length:897
Mass (Da):98,508
Last modified:September 21, 2011 - v1
Checksum:i02AD945FC7BC8E24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002665 Genomic DNA. Translation: AEI11714.1.
RefSeqiWP_013883233.1. NC_015671.1.

Genome annotation databases

EnsemblBacteriaiAEI11714; AEI11714; Celgi_1195.
KEGGicga:Celgi_1195.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiF8A1Q7_CELGA
AccessioniPrimary (citable) accession number: F8A1Q7
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 7, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported