F7ZB42 (F7ZB42_ROSLO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Exodeoxyribonuclease 7 large subunit HAMAP-Rule MF_00378
EC=3.1.11.6 HAMAP-Rule MF_00378

Alternative name(s):
Exodeoxyribonuclease VII large subunit HAMAP-Rule MF_00378

Gene names

Name:	xseA HAMAP-Rule MF_00378 EMBL AEI93035.1
Ordered Locus Names:	RLO149_c010260 EMBL AEI93035.1

Organism

Roseobacter litoralis (strain ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149) [Complete proteome] [HAMAP] EMBL AEI93035.1

Taxonomic identifier

391595 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Roseobacter › Roseobacter litoralis

Protein attributes

Sequence length	513 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. SAAS SAAS025824 HAMAP-Rule MF_00378
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00378 Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates. SAAS SAAS025824
Subunit structure	Heterooligomer composed of large and small subunits By similarity. SAAS SAAS025824 HAMAP-Rule MF_00378
Subcellular location	Cytoplasm By similarity SAAS SAAS025824 HAMAP-Rule MF_00378.
Sequence similarities	Belongs to the XseA family. HAMAP-Rule MF_00378

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS025824 HAMAP-Rule MF_00378
Molecular function	Exonuclease SAAS SAAS025824 HAMAP-Rule MF_00378 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular_function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F7ZB42 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: 0327FBE9C1C3DFCD	FASTA	513	56,309
	10 20 30 40 50 60 MDLLDDPTPG QNTPEFTVSE ISGAVKRTLE GEFGRVRVRG EVSRVIKARS GHMYYDIKDD 70 80 90 100 110 120 RNQLSCTTWK GQVARLSVIP EEGLEVVVTG RITAYGAQSK YNMNVDEVAV AGKGALMALL 130 140 150 160 170 180 EKRKKQLEAE GLFEASRKRP LPYLPEIIGV VTSPTGAVIR DILHRLRDRF PRKVLIWPVA 190 200 210 220 230 240 VQGEKCAPEV AAAIAGFNAL VPGGALPRPD LIIVARGGGS VEDLWGFNEE SVARAAAASD 250 260 270 280 290 300 IPLISAVGHE TDTTLIDFVS DKRAPTPTAA AELAVPVRHE LIAWVEQQDA RMRQALSQGL 310 320 330 340 350 360 TRRDQRLRDV ARALPRPDSL LESPRQLVDT RGARLAPALM SGVQRRKIRL ADVSGSLRPA 370 380 390 400 410 420 MLTRAVQAED RQLKEKARRL QPALLRALAT RKEQLETRVR RYRPAVLEQD YRRKKQHFED 430 440 450 460 470 480 VVQRLGKVGE QNLDAARRKL DALGRLNETL SYKATLARGF AVVRSDGAVV TDSKTAKTAS 490 500 510 SLEIQFADGR VTVGGKTASK KSAGKPPEQG SLF

References

[1]

"Comparative genome analysis and genome-guided physiological analysis of Roseobacter litoralis." Kalhoefer D., Thole S., Voget S., Lehmann R., Liesegang H., Wollher A., Daniel R., Simon M., Brinkhoff T. BMC Genomics 12:324-324(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002623 Genomic DNA. Translation: AEI93035.1.
RefSeq	YP_004689998.1. NC_015730.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEI93035; AEI93035; RLO149_c010260.
GeneID	10949415.
KEGG	rli:RLO149_c010260.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03601.
Enzyme and pathway databases
BioCyc	RLIT391595:GJEH-1020-MONOMER.
Family and domain databases
HAMAP	MF_00378. Exonuc_7_L.
InterPro	IPR003753. Exonuc_VII_L. IPR020579. Exonuc_VII_lsu_C. IPR025824. OB-fold_nuc-bd_dom. [Graphical view]
Pfam	PF02601. Exonuc_VII_L. 1 hit. PF13742. tRNA_anti_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00237. xseA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F7ZB42_ROSLO

Accession

Primary (citable) accession number: F7ZB42

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)