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F7Z9L7

- F7Z9L7_MYCBH

UniProt

F7Z9L7 - F7Z9L7_MYCBH

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Protein

Thymidine kinase

Gene

tdk

Organism
Mycoplasma bovis (strain Hubei-1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891Proton acceptorUniRule annotation
Metal bindingi145 – 1451ZincUniRule annotation
Metal bindingi148 – 1481ZincUniRule annotation
Metal bindingi176 – 1761ZincUniRule annotation
Metal bindingi179 – 1791ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 228ATPUniRule annotation
Nucleotide bindingi88 – 914ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMBOV956483:GHJX-784-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:MMB_0754Imported
OrganismiMycoplasma bovis (strain Hubei-1)Imported
Taxonomic identifieri956483 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000498: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.
OMAiQAICLSC.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F7Z9L7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYLKSGLGQL EVITGPMFSG KTEELLKRIN ILKIAGINSL VIKPKFDTRF
60 70 80 90 100
SKDEIVSRTR ARHKAINVAN SKEILKYWNP DYMCVAIDEV NFMDEDILTV
110 120 130 140 150
IDELIVKGVR VICSGLDMDF KRRPFDVMAR VLASADNILK LKAVCLECKS
160 170 180 190
DAGFSFRKVK SDELNLLGDS EYEARCRVCH IKGEAKKAMR
Length:190
Mass (Da):21,538
Last modified:September 21, 2011 - v1
Checksum:i8BCF3092CEEC1CD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002513 Genomic DNA. Translation: AEI90466.1.
RefSeqiWP_013955060.1. NC_015725.1.
YP_004683801.1. NC_015725.1.

Genome annotation databases

EnsemblBacteriaiAEI90466; AEI90466; MMB_0754.
GeneIDi10923710.
KEGGimbh:MMB_0754.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002513 Genomic DNA. Translation: AEI90466.1 .
RefSeqi WP_013955060.1. NC_015725.1.
YP_004683801.1. NC_015725.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEI90466 ; AEI90466 ; MMB_0754 .
GeneIDi 10923710.
KEGGi mbh:MMB_0754.

Phylogenomic databases

KOi K00857.
OMAi QAICLSC.

Enzyme and pathway databases

BioCyci MBOV956483:GHJX-784-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Mycoplasma bovis strain Hubei-1."
    Li Y., Zheng H., Liu Y., Jiang Y., Xin J., Chen W., Song Z.
    PLoS ONE 6:E20999-E20999(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hubei-1Imported.

Entry informationi

Entry nameiF7Z9L7_MYCBH
AccessioniPrimary (citable) accession number: F7Z9L7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 26, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3