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F7Z9L7

- F7Z9L7_MYCBH

UniProt

F7Z9L7 - F7Z9L7_MYCBH

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Protein
Thymidine kinase
Gene
tdk, MMB_0754
Organism
Mycoplasma bovis (strain Hubei-1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891Proton acceptor By similarityUniRule annotation
Metal bindingi145 – 1451Zinc By similarityUniRule annotation
Metal bindingi148 – 1481Zinc By similarityUniRule annotation
Metal bindingi176 – 1761Zinc By similarityUniRule annotation
Metal bindingi179 – 1791Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 228ATP By similarityUniRule annotation
Nucleotide bindingi88 – 914ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMBOV956483:GHJX-784-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:MMB_0754Imported
OrganismiMycoplasma bovis (strain Hubei-1)Imported
Taxonomic identifieri956483 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000498: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00857.
OMAiQAICLSC.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F7Z9L7-1 [UniParc]FASTAAdd to Basket

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MYLKSGLGQL EVITGPMFSG KTEELLKRIN ILKIAGINSL VIKPKFDTRF    50
SKDEIVSRTR ARHKAINVAN SKEILKYWNP DYMCVAIDEV NFMDEDILTV 100
IDELIVKGVR VICSGLDMDF KRRPFDVMAR VLASADNILK LKAVCLECKS 150
DAGFSFRKVK SDELNLLGDS EYEARCRVCH IKGEAKKAMR 190
Length:190
Mass (Da):21,538
Last modified:September 21, 2011 - v1
Checksum:i8BCF3092CEEC1CD4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002513 Genomic DNA. Translation: AEI90466.1.
RefSeqiWP_013955060.1. NC_015725.1.
YP_004683801.1. NC_015725.1.

Genome annotation databases

EnsemblBacteriaiAEI90466; AEI90466; MMB_0754.
GeneIDi10923710.
KEGGimbh:MMB_0754.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002513 Genomic DNA. Translation: AEI90466.1 .
RefSeqi WP_013955060.1. NC_015725.1.
YP_004683801.1. NC_015725.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEI90466 ; AEI90466 ; MMB_0754 .
GeneIDi 10923710.
KEGGi mbh:MMB_0754.

Phylogenomic databases

KOi K00857.
OMAi QAICLSC.

Enzyme and pathway databases

BioCyci MBOV956483:GHJX-784-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Mycoplasma bovis strain Hubei-1."
    Li Y., Zheng H., Liu Y., Jiang Y., Xin J., Chen W., Song Z.
    PLoS ONE 6:E20999-E20999(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hubei-1Imported.

Entry informationi

Entry nameiF7Z9L7_MYCBH
AccessioniPrimary (citable) accession number: F7Z9L7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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