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F7YTY1

- F7YTY1_9THEM

UniProt

F7YTY1 - F7YTY1_9THEM

Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Theth_1510

Organism
Thermotoga thermarum DSM 5069
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciTTHE688269:GHXV-1543-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
    Gene namesi
    ORF Names:Theth_1510Imported
    OrganismiThermotoga thermarum DSM 5069Imported
    Taxonomic identifieri688269 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
    ProteomesiUP000006804: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    KOiK01921.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F7YTY1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKVAVVFDM VNLDEERKRM IDAVASALSK KFEVEKLPFD DDFVKKVKKF    50
    DAVFNLSTAY KQIHVPAILD VLNIPYTGSD ALAHALCIDK VITKTILVQN 100
    NVPTPEFVAV EVGQLPPQID FYPAIVKPSR QGSAKGIHAD SVVHNYDELC 150
    RIVKRVHEQF NEPALVEKFI EGKELSVGIV AGEVLPILEI DFSELGEGLE 200
    RFYSYRVKHY YGDKTKYYCP ARIDETVRKK IEFYAKRAFE ALRLKNYARM 250
    DLRLKDDEIY FLEVNSLPML TPGYSDIIKM AEATGYSYDE LILKIFEDGV 300
    MKCFGT 306
    Length:306
    Mass (Da):34,914
    Last modified:September 21, 2011 - v1
    Checksum:iA9F39B1BA74A9375
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002351 Genomic DNA. Translation: AEH51563.1.
    RefSeqiYP_004660659.1. NC_015707.1.

    Genome annotation databases

    EnsemblBacteriaiAEH51563; AEH51563; Theth_1510.
    GeneIDi10886283.
    KEGGitta:Theth_1510.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002351 Genomic DNA. Translation: AEH51563.1 .
    RefSeqi YP_004660659.1. NC_015707.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEH51563 ; AEH51563 ; Theth_1510 .
    GeneIDi 10886283.
    KEGGi tta:Theth_1510.

    Phylogenomic databases

    KOi K01921.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci TTHE688269:GHXV-1543-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DSM 5069Imported.

    Entry informationi

    Entry nameiF7YTY1_9THEM
    AccessioniPrimary (citable) accession number: F7YTY1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3