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F7YFI8

- F7YFI8_MESOW

UniProt

F7YFI8 - F7YFI8_MESOW

Protein

Alanine racemase

Gene

Mesop_1250

Organism
Mesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei53 – 531Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei152 – 1521SubstrateUniRule annotation
    Active sitei274 – 2741Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei320 – 3201Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMOPP536019:GH56-1259-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Mesop_1250Imported
    OrganismiMesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075)Imported
    Taxonomic identifieri536019 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
    ProteomesiUP000001623: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei53 – 531N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF7YFI8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F7YFI8-1 [UniParc]FASTAAdd to Basket

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    MNDASKRSLS GDTAGVSEAA AGAILTIDLG AIRENYRRLK AQLGGVRCAG    50
    VVKADGYGLG ATQVASALMK DGCDTFFVAL LAEGISLRKA IGAGPDIYVL 100
    NGLPPGSEPE AVAAGLCAVI NSGAQLKAWR AAAHGAGRQL PAAIQVDSGM 150
    SRLGMAPAEV EAVVEDTGAF EGIDVRYVTS HLACADEPRH PANEQQRLAF 200
    ERLRALLPAA PASLANSSGI FLGPRYHYDL ARPGAALYGI NPTPDATNPM 250
    LPVVGLQAKV AQTRGIEKGT GVGYGHTYHA EGPRSLATIS FGYADGWLRR 300
    SASAAWFEGV RLPFLGRVSM DSIILDVSAL SPGKLREGDL VELLGPAQSV 350
    DDAAGHAGTI GYEILASLGT RFHRRYVGG 379
    Length:379
    Mass (Da):39,342
    Last modified:September 21, 2011 - v1
    Checksum:i1BAB425DE1386D64
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002279 Genomic DNA. Translation: AEH85733.1.
    RefSeqiYP_004609827.1. NC_015675.1.

    Genome annotation databases

    EnsemblBacteriaiAEH85733; AEH85733; Mesop_1250.
    GeneIDi10825063.
    KEGGimop:Mesop_1250.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002279 Genomic DNA. Translation: AEH85733.1 .
    RefSeqi YP_004609827.1. NC_015675.1.

    3D structure databases

    ProteinModelPortali F7YFI8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEH85733 ; AEH85733 ; Mesop_1250 .
    GeneIDi 10825063.
    KEGGi mop:Mesop_1250.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci MOPP536019:GH56-1259-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LMG 24607 / HAMBI 3007 / WSM2075Imported.

    Entry informationi

    Entry nameiF7YFI8_MESOW
    AccessioniPrimary (citable) accession number: F7YFI8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3