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F7YAX8 (F7YAX8_MESOW) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribulose bisphosphate carboxylase large chain HAMAP-Rule MF_01338
Short name=RuBisCO large subunit HAMAP-Rule MF_01338
EC=4.1.1.39 HAMAP-Rule MF_01338
Gene names
Name:cbbL HAMAP-Rule MF_01338
Ordered Locus Names:Mesop_5541
OrganismMesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075) [Complete proteome] [HAMAP]
Taxonomic identifier536019 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium ›

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site By similarity. HAMAP-Rule MF_01338

Catalytic activity

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O. HAMAP-Rule MF_01338

3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2. HAMAP-Rule MF_01338

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01338

Subunit structure

Heterohexadecamer of 8 large chains and 8 small chains By similarity. HAMAP-Rule MF_01338

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel" By similarity. HAMAP-Rule MF_01338

Sequence similarities

Belongs to the RuBisCO large chain family. Type I subfamily. HAMAP-Rule MF_01338

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1781Proton acceptor By similarity HAMAP-Rule MF_01338
Active site2961Proton acceptor By similarity HAMAP-Rule MF_01338
Metal binding2041Magnesium; via carbamate group By similarity HAMAP-Rule MF_01338
Metal binding2061Magnesium By similarity HAMAP-Rule MF_01338
Metal binding2071Magnesium By similarity HAMAP-Rule MF_01338
Binding site1261Substrate; in homodimeric partner By similarity HAMAP-Rule MF_01338
Binding site1761Substrate By similarity HAMAP-Rule MF_01338
Binding site1801Substrate By similarity HAMAP-Rule MF_01338
Binding site2971Substrate By similarity HAMAP-Rule MF_01338
Binding site3291Substrate By similarity HAMAP-Rule MF_01338
Binding site3811Substrate By similarity HAMAP-Rule MF_01338
Site3361Transition state stabilizer By similarity HAMAP-Rule MF_01338

Amino acid modifications

Modified residue2041N6-carboxylysine By similarity HAMAP-Rule MF_01338

Sequences

Sequence LengthMass (Da)Tools
F7YAX8 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 7157BF99C61ECE9F

FASTA48753,933
        10         20         30         40         50         60 
MMTVQPTELK GKERYRAGVL KYAQMGYWNG DYVPKDTDLI ALFRITPQDG VDPIEAAAAV 

        70         80         90        100        110        120 
AGESSTATWT VVWTDRLTAA DQYRAKAYRV DPVPGRPGEY FCYVAYDLIL FEPGSIANLT 

       130        140        150        160        170        180 
ASIIGNVFSF KPLMAARLED MRLPVAYVKT FKGPPTGIVA ERERLDKFGR PLLGATTKPK 

       190        200        210        220        230        240 
LGLSGKNYGR VVYEGLKGGL DFMKDDENIN SQPFMHWRDR FLYCMEAVNR AAAETGEIKG 

       250        260        270        280        290        300 
HYLNITAGTM EEIYRRAEFA KELGSCIVMI DLIIGYTAIQ SISEWCRRND MILHLHRAGH 

       310        320        330        340        350        360 
GTYTRQKNHG ISFRVIAKWM RLAGVDHIHA GTAVGKLEGD PMTVQGYYNV CRELKNEVDF 

       370        380        390        400        410        420 
PRGIFFEQDW ADTLKVMPVA SGGIHAGQMH QLLDLFGDDV VLQFGGGTIG HPMGIQAGAT 

       430        440        450        460        470        480 
ANRVALEAMV LARNEGRDIA AEGPEILRAA ARWCKPLEAA LDVWGNISFN YQSTDTSDFV 


PTPAVAV

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References

[1]"Complete sequence of Mesorhizobium opportunistum WSM2075."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Misra M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Mavrommatis K.M., Tiwari R.P. expand/collapse author list , Howieson J.G., O'Hara G.W., Nandasena K.G., Woyke T.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LMG 24607 / HAMBI 3007 / WSM2075.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002279 Genomic DNA. Translation: AEH89954.1.
RefSeqYP_004614048.1. NC_015675.1.

3D structure databases

ProteinModelPortalF7YAX8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH89954; AEH89954; Mesop_5541.
GeneID10829406.
KEGGmop:Mesop_5541.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01601.

Enzyme and pathway databases

BioCycMOPP536019:GH56-5602-MONOMER.

Family and domain databases

Gene3D3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPMF_01338. RuBisCO_L_type1.
InterProIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMSSF51649. RuBisCO_large. 1 hit.
SSF54966. RuBisCO_large. 1 hit.
PROSITEPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF7YAX8_MESOW
AccessionPrimary (citable) accession number: F7YAX8
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 1, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info