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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) (Methanohalophilus zhilinae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMZHI679901:GHPZ-977-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Mzhil_0941Imported
OrganismiMethanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) (Methanohalophilus zhilinae)Imported
Taxonomic identifieri679901 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosalsum
ProteomesiUP000006622 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi679901.Mzhil_0941.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiQSSFKYD.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

F7XLE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSNKMYPKV MCTQHPDSIS RYISTQEETY EAVEAATKYG CDEYMPDYEG
60 70 80 90 100
KTTPYHQSAQ IISKFIEETD LVLGKDIFIT PRVPSAVHEN LFRQLMVMMA
110 120 130 140 150
IAEANYISYK HTGIQAIDEL VHPMTSSVGQ IVESQQHMID VTNLAKKEFS
160 170 180 190 200
FEMEAPRIIP LIEEVPKHLN AKEIIGNTIT AYQEQLNQTP EKYRVFLGKS
210 220 230 240 250
DSALTFGHVA STLSCKYAIS ELHELEADTG IPIGIIFGTG SLPFRGHMSL
260 270 280 290 300
ENKDNFFMEY RGIDTVTLQS ALRFDHEKGD AEQFVKYARD ELSKSPDILS
310 320 330 340 350
AQEKEEFINI IGIFGASYNR AIQQFSSTIN SIADFLPQQR DRLMRGGSTG
360 370 380 390 400
YARDLPDSII VSRLCQSDIG NELQASMACG SMNLPRAIKF TGALYSIGIP
410 420 430 440 450
PEIIGTGSAL EKVREKLGDS VYERLLTRYF PSLQTDLRFA FQYLDTNTAS
460 470 480 490 500
RFLSDSLHES IREEVDILRN IFDIETQCDP SYRMLLEMAN PHLLCAADSN
510 520
CIMDADLLQL TRSIMIKMGK MRKSLG
Length:526
Mass (Da):59,272
Last modified:September 21, 2011 - v1
Checksum:iB8CDB5EA8EF15EF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002101 Genomic DNA. Translation: AEH60801.1.
RefSeqiWP_013898240.1. NC_015676.1.
YP_004616020.1. NC_015676.1.

Genome annotation databases

EnsemblBacteriaiAEH60801; AEH60801; Mzhil_0941.
GeneIDi10822563.
KEGGimzh:Mzhil_0941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002101 Genomic DNA. Translation: AEH60801.1.
RefSeqiWP_013898240.1. NC_015676.1.
YP_004616020.1. NC_015676.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi679901.Mzhil_0941.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEH60801; AEH60801; Mzhil_0941.
GeneIDi10822563.
KEGGimzh:Mzhil_0941.

Phylogenomic databases

KOiK01595.
OMAiQSSFKYD.

Enzyme and pathway databases

BioCyciMZHI679901:GHPZ-977-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 4017 / NBRC 107636 / OCM 62 / WeN5Imported.

Entry informationi

Entry nameiF7XLE0_METZD
AccessioniPrimary (citable) accession number: F7XLE0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 24, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.