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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) (Methanohalophilus zhilinae)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationImported
Biological processCarbon dioxide fixationUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMZHI679901:G1GYM-959-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Mzhil_0941Imported
OrganismiMethanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) (Methanohalophilus zhilinae)Imported
Taxonomic identifieri679901 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosalsum
Proteomesi
  • UP000006622 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi679901.Mzhil_0941

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04435 Archaea
COG1892 LUCA
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

F7XLE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSNKMYPKV MCTQHPDSIS RYISTQEETY EAVEAATKYG CDEYMPDYEG
60 70 80 90 100
KTTPYHQSAQ IISKFIEETD LVLGKDIFIT PRVPSAVHEN LFRQLMVMMA
110 120 130 140 150
IAEANYISYK HTGIQAIDEL VHPMTSSVGQ IVESQQHMID VTNLAKKEFS
160 170 180 190 200
FEMEAPRIIP LIEEVPKHLN AKEIIGNTIT AYQEQLNQTP EKYRVFLGKS
210 220 230 240 250
DSALTFGHVA STLSCKYAIS ELHELEADTG IPIGIIFGTG SLPFRGHMSL
260 270 280 290 300
ENKDNFFMEY RGIDTVTLQS ALRFDHEKGD AEQFVKYARD ELSKSPDILS
310 320 330 340 350
AQEKEEFINI IGIFGASYNR AIQQFSSTIN SIADFLPQQR DRLMRGGSTG
360 370 380 390 400
YARDLPDSII VSRLCQSDIG NELQASMACG SMNLPRAIKF TGALYSIGIP
410 420 430 440 450
PEIIGTGSAL EKVREKLGDS VYERLLTRYF PSLQTDLRFA FQYLDTNTAS
460 470 480 490 500
RFLSDSLHES IREEVDILRN IFDIETQCDP SYRMLLEMAN PHLLCAADSN
510 520
CIMDADLLQL TRSIMIKMGK MRKSLG
Length:526
Mass (Da):59,272
Last modified:September 21, 2011 - v1
Checksum:iB8CDB5EA8EF15EF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002101 Genomic DNA Translation: AEH60801.1
RefSeqiWP_013898240.1, NC_015676.1

Genome annotation databases

EnsemblBacteriaiAEH60801; AEH60801; Mzhil_0941
GeneIDi10822563
KEGGimzh:Mzhil_0941

Similar proteinsi

Entry informationi

Entry nameiF7XLE0_METZD
AccessioniPrimary (citable) accession number: F7XLE0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health