Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

F7XK86 (F7XK86_METZD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length569 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196 HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2471N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2451ATP By similarity HAMAP-Rule MF_00407
Binding site2521ATP By similarity HAMAP-Rule MF_00407
Binding site2671ATP By similarity HAMAP-Rule MF_00407
Binding site2971ATP By similarity HAMAP-Rule MF_00407
Binding site3351ATP By similarity HAMAP-Rule MF_00407
Binding site4121ATP By similarity HAMAP-Rule MF_00407
Binding site4181ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
F7XK86 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 20C847FD2C44E2ED

FASTA56964,974
        10         20         30         40         50         60 
MASLKELVEL YVEMENTSSH KKIVGLLTSF FRSLDPDDVR TAAYLVLGTV GPEYEDTELG 

        70         80         90        100        110        120 
IREKLAIRSI ADAFGISRQK VEKTYSDTGD LGDAAFEFSS NKNSDLTIRD VMDCLTQIKN 

       130        140        150        160        170        180 
TSGEGSQQKK IELLAEILAR ASAMEAKYIM RITLGELRLG FGEQFVLSAL AMAFTGDDKN 

       190        200        210        220        230        240 
TVYLEEAYNV CTDIGQLAES VSEYGLASIK RFSVKIGRPV RSMLAKRVDK FENLNDKFPE 

       250        260        270        280        290        300 
QMAAEEKYDG ERIQVHIINE NIQIFSRRLD NITDQFPDVV DAVKKHIKAE KAVLDGEVIA 

       310        320        330        340        350        360 
FRNENINSFQ ELMQRRRKYD VEEYVDKVPV VAYMFDIIYL NGKSYLKVPY PHRRTALEEH 

       370        380        390        400        410        420 
LEENEKIRLV ERTVSADFNE IRSFFDRCID KGLEGIIIKS VADNSFYQPG KRGWLWVKWK 

       430        440        450        460        470        480 
KEYAEDVRDT FDLIIVGFYS GKGKRQGLFG SLLCAVLNKE KNQYETFTRV GTGFTDQDLE 

       490        500        510        520        530        540 
EISELLNKKK IKKKPPNLVV EKEMVPDSYI DPSVVIEVLG SQVTESPHHT AGKNKSDKGY 

       550        560 
ALRFPRFLRM RYDKGPLDVT TIEEVRNLL 

« Hide

References

[1]"The complete genome of Methanosalsum zhilinae DSM 4017."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ovchinnikova G., Daligault H., Detter J.C., Han C., Tapia R., Larimer F., Land M. expand/collapse author list , Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schueler E., Brambilla E., Klenk H.-P., Eisen J.A.
Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 4017 / NBRC 107636 / OCM 62 / WeN5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002101 Genomic DNA. Translation: AEH60551.1.
RefSeqYP_004615770.1. NC_015676.1.

3D structure databases

ProteinModelPortalF7XK86.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH60551; AEH60551; Mzhil_0684.
GeneID10822295.
KEGGmzh:Mzhil_0684.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK10747.
OMAYIARFVV.

Enzyme and pathway databases

BioCycMZHI679901:GHPZ-709-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF7XK86_METZD
AccessionPrimary (citable) accession number: F7XK86
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 19, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)