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F7X514

- F7X514_SINMM

UniProt

F7X514 - F7X514_SINMM

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Protein

Alanine racemase

Gene

alr

Organism
Sinorhizobium meliloti (strain SM11)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei54 – 541Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei151 – 1511SubstrateUniRule annotation
Active sitei273 – 2731Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei332 – 3321Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSMEL707241:GLKB-2536-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:SM11_chr2537Imported
OrganismiSinorhizobium meliloti (strain SM11)Imported
Taxonomic identifieri707241 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000009045: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei54 – 541N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF7X514.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F7X514-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYCCRYRPRR VFGMQSPEFL SASSRLTVDL TALADNWRAM NERSGKARAA
60 70 80 90 100
AVLKADAYGL GVVHAAPALY AAGARDFFVA SVEEGADLRP LVPDGRIYIL
110 120 130 140 150
AGMWPGNEEL FFENDLVPII NSEEQLAVFM AALSERGDHP CVLHVDTGMN
160 170 180 190 200
RLGLSPEEAL ALAHDPARPA SFSPVLVMSH LACADDPGHP MNRYQLQRFR
210 220 230 240 250
EVTAAFEGVP ASLANSGGVF LGADYHFDLT RPGIAVYGGE AVNGAVNPMK
260 270 280 290 300
AVVTAEARIV QVRTVPSGGT ASYGASVRFG RDSRIATVAI GYADGYHRSV
310 320 330 340 350
SGGGVTLRQA MPSGAFGFLH GMKVPHVGRV TMDLSLFDVT DLPEAAVRAG
360 370 380 390
DYIEVFGRNV VIDDVARAGG TIGYELLTSL GRRYHRTYVG GA
Length:392
Mass (Da):41,923
Last modified:September 21, 2011 - v1
Checksum:iD8D9511570C83B50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001830 Genomic DNA. Translation: AEH79790.1.
RefSeqiWP_014529833.1. NC_017325.1.
YP_005721051.1. NC_017325.1.

Genome annotation databases

EnsemblBacteriaiAEH79790; AEH79790; SM11_chr2537.
GeneIDi12310982.
KEGGismx:SM11_chr2537.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001830 Genomic DNA. Translation: AEH79790.1 .
RefSeqi WP_014529833.1. NC_017325.1.
YP_005721051.1. NC_017325.1.

3D structure databases

ProteinModelPortali F7X514.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEH79790 ; AEH79790 ; SM11_chr2537 .
GeneIDi 12310982.
KEGGi smx:SM11_chr2537.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci SMEL707241:GLKB-2536-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the dominant Sinorhizobium meliloti field isolate SM11 extends the S. meliloti pan-genome."
    Schneiker-Bekel S., Wibberg D., Bekel T., Blom J., Linke B., Neuweger H., Stiens M., Vorholter F.J., Weidner S., Goesmann A., Puhler A., Schluter A.
    J. Biotechnol. 155:20-33(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SM11Imported.

Entry informationi

Entry nameiF7X514_SINMM
AccessioniPrimary (citable) accession number: F7X514
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 26, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3