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F7WS65

- F7WS65_MYCTD

UniProt

F7WS65 - F7WS65_MYCTD

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Protein
Elongation factor Tu
Gene
tuf, CCDC5180_0628, CFBR_0720
Organism
Mycobacterium tuberculosis (strain CCDC5180)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi83 – 875GTP By similarityUniRule annotation
Nucleotide bindingi138 – 1414GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMTUB443150:GLGS-636-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:CCDC5180_0628Imported
ORF Names:CFBR_0720Imported
OrganismiMycobacterium tuberculosis (strain CCDC5180)Imported
Taxonomic identifieri443150 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000000302: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiF7WS65.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF7WS65.
SMRiF7WS65. Positions 5-395.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK02358.
OMAiGDHATFG.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F7WS65-1 [UniParc]FASTAAdd to Basket

« Hide

MAKAKFQRTK PHVNIGTIGH VDHGKTTLTA AITKVLHDKF PDLNETKAFD    50
QIDNAPEERQ RGITINIAHV EYQTDKRHYA HVDAPGHADY IKNMITGAAQ 100
MDGAILVVAA TDGPMPQTRE HVLLARQVGV PYILVALNKA DAVDDEELLE 150
LVEMEVRELL AAQEFDEDAP VVRVSALKAL EGDAKWVASV EELMNAVDES 200
IPDPVRETDK PFLMPVEDVF TITGRGTVVT GRVERGVINV NEEVEIVGIR 250
PSTTKTTVTG VEMFRKLLDQ GQAGDNVGLL LRGVKREDVE RGQVVTKPGT 300
TTPHTEFEGQ VYILSKDEGG RHTPFFNNYR PQFYFRTTDV TGVVTLPEGT 350
EMVMPGDNTN ISVKLIQPVA MDEGLRFAIR EGGRTVGAGR VTKIIK 396
Length:396
Mass (Da):43,594
Last modified:September 21, 2011 - v1
Checksum:i85F9012F364692FF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001642 Genomic DNA. Translation: AEJ49465.1.
CP002885 Genomic DNA. Translation: AHJ53805.1.
RefSeqiYP_005908460.1. NC_017522.1.

Genome annotation databases

EnsemblBacteriaiAEJ49465; AEJ49465; CCDC5180_0628.
GeneIDi12498469.
KEGGimtl:CCDC5180_0628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001642 Genomic DNA. Translation: AEJ49465.1 .
CP002885 Genomic DNA. Translation: AHJ53805.1 .
RefSeqi YP_005908460.1. NC_017522.1.

3D structure databases

ProteinModelPortali F7WS65.
SMRi F7WS65. Positions 5-395.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F7WS65.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEJ49465 ; AEJ49465 ; CCDC5180_0628 .
GeneIDi 12498469.
KEGGi mtl:CCDC5180_0628.

Phylogenomic databases

KOi K02358.
OMAi GDHATFG.

Enzyme and pathway databases

BioCyci MTUB443150:GLGS-636-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete Genome Sequences of Mycobacterium tuberculosis Strains CCDC5079 and CCDC5080, Which Belong to the Beijing Family."
    Zhang Y., Chen C., Liu J., Deng H., Pan A., Zhang L., Zhao X., Huang M., Lu B., Dong H., Du P., Chen W., Wan K.
    J. Bacteriol. 193:5591-5592(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCDC5180Imported.
  2. "Beijing/W Lineage of Mycobacterium tuberculosis Develop Totally Drug Resistant Phenotype by Reductive Evolution."
    Wan K., Liu H., Tang B., Jiang Y., Zheng H., Zhang Y., Lv B., Liu Z., Zhao X., Dong H., Zhao G.
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CCDC5180Imported.

Entry informationi

Entry nameiF7WS65_MYCTD
AccessioniPrimary (citable) accession number: F7WS65
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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