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F7WS13

- F7WS13_MYCTD

UniProt

F7WS13 - F7WS13_MYCTD

Protein

Glutamate decarboxylase

Gene

gadB

Organism
Mycobacterium tuberculosis (strain CCDC5180)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMTUB443150:GLGS-3173-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:gadBImported
    Ordered Locus Names:CCDC5180_3132Imported
    ORF Names:CFBR_3654Imported
    OrganismiMycobacterium tuberculosis (strain CCDC5180)Imported
    Taxonomic identifieri443150 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000000302: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiF7WS13.

    Structurei

    3D structure databases

    ProteinModelPortaliF7WS13.
    SMRiF7WS13. Positions 12-447.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.
    OMAiAQYYTFL.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F7WS13-1 [UniParc]FASTAAdd to Basket

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    MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM    50
    LDGSSRLNLA TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV 100
    SMVADLFHAE GLRDHDPTSA TGVSTIGSSE AVMLGGLALK WRWRQRVGSW 150
    KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY LPMERGRYVI TPEQVLAAVD 200
    ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP VHVDAASGGF 250
    VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 300
    VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT 350
    ARWLGDQLRE VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW 400
    QVPAYTMPDN ATDVAVLRIV VREGLSADLA RALHDDAVTA LAALDKVKPG 450
    GHFDAQHFAH 460
    Length:460
    Mass (Da):50,780
    Last modified:September 21, 2011 - v1
    Checksum:iB5DA3156D4C7CB4F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001642 Genomic DNA. Translation: AEJ51969.1.
    CP002885 Genomic DNA. Translation: AHJ56739.1.
    RefSeqiYP_005910964.1. NC_017522.1.

    Genome annotation databases

    EnsemblBacteriaiAEJ51969; AEJ51969; CCDC5180_3132.
    GeneIDi12501009.
    KEGGimtl:CCDC5180_3132.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001642 Genomic DNA. Translation: AEJ51969.1 .
    CP002885 Genomic DNA. Translation: AHJ56739.1 .
    RefSeqi YP_005910964.1. NC_017522.1.

    3D structure databases

    ProteinModelPortali F7WS13.
    SMRi F7WS13. Positions 12-447.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F7WS13.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEJ51969 ; AEJ51969 ; CCDC5180_3132 .
    GeneIDi 12501009.
    KEGGi mtl:CCDC5180_3132.

    Phylogenomic databases

    KOi K01580.
    OMAi AQYYTFL.

    Enzyme and pathway databases

    BioCyci MTUB443150:GLGS-3173-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequences of Mycobacterium tuberculosis strains CCDC5079 and CCDC5080, which belong to the Beijing family."
      Zhang Y., Chen C., Liu J., Deng H., Pan A., Zhang L., Zhao X., Huang M., Lu B., Dong H., Du P., Chen W., Wan K.
      J. Bacteriol. 193:5591-5592(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CCDC5180Imported.
    2. "Beijing/W Lineage of Mycobacterium tuberculosis Develop Totally Drug Resistant Phenotype by Reductive Evolution."
      Wan K., Liu H., Tang B., Jiang Y., Zheng H., Zhang Y., Lv B., Liu Z., Zhao X., Dong H., Zhao G.
      Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CCDC5180Imported.

    Entry informationi

    Entry nameiF7WS13_MYCTD
    AccessioniPrimary (citable) accession number: F7WS13
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3