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Protein

Histone-lysine N-methyltransferase

Gene

SMAC_07534

Organism
Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N6-methyl-L-lysine-[histone].PROSITE-ProRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
Gene namesi
ORF Names:SMAC_07534Imported
OrganismiSordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)Imported
Taxonomic identifieri771870 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeSordaria
Proteomesi
  • UP000001881 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:SMAC_07534

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi771870.XP_003344526.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1172 – 1289SETInterPro annotationAdd BLAST118
Domaini1298 – 1314Post-SETInterPro annotationAdd BLAST17

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili584 – 604Sequence analysisAdd BLAST21
Coiled coili904 – 924Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1080 Eukaryota
COG2940 LUCA
InParanoidiF7VTR0
KOiK11422
OrthoDBiEOG092C3T9B

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR024657 COMPASS_Set1_N-SET
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR003616 Post-SET_dom
IPR035979 RBD_domain_sf
IPR017111 Set1
IPR024636 SET_assoc
IPR001214 SET_dom
PANTHERiPTHR22884:SF462 PTHR22884:SF462, 1 hit
PfamiView protein in Pfam
PF11764 N-SET, 1 hit
PF00856 SET, 1 hit
PF11767 SET_assoc, 1 hit
PIRSFiPIRSF037104 Histone_H3-K4_mtfrase_Set1_fun, 2 hits
SMARTiView protein in SMART
SM01291 N-SET, 1 hit
SM00508 PostSET, 1 hit
SM00317 SET, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50868 POST_SET, 1 hit
PS51572 SAM_MT43_1, 1 hit
PS50280 SET, 1 hit

Sequencei

Sequence statusi: Complete.

F7VTR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRSSGASFA QFFPAAPRAA RDRATERERA RMRAQASPPT QPVDTNGHRT
60 70 80 90 100
PLSSFTSNRS DDGASPGRSH ITSLNHSSSA GADATRPPLL EDSESLPGDT
110 120 130 140 150
LNTVGSASSH ASTSSSIFSS STRQPAMASA SVRNSHTHNS NTPLTTADSP
160 170 180 190 200
SSLYLSTSLH AKPHSVSPHH ADKQNGLTPT LNGSATEFLV PLPDGTDRVP
210 220 230 240 250
LRNPSRSVLC TICTYDPLLD KKLSSSEKKR RNLYTRIMAW YNDEDDASPS
260 270 280 290 300
DPRLAHGGKL SYINVNFHLP KAQLIDAPSN LKPYPYDPKT SCGPGPPVQI
310 320 330 340 350
LVRGFNPLIA FTKVTTIFAS FGDIAESSNK MHPETGSYLG FATIRYKDSK
360 370 380 390 400
PTPSRPVPVP AHQAARRAVR GMHGRRIEAS QVRVEFDPEG RKSKALMEAV
410 420 430 440 450
LKKSRETSQP PSAAYKIPTG PKPRAGEVIP GPPPTAPKGP AAHRALGGSE
460 470 480 490 500
AGWTSTKPRH PSIIENEPIL NHIKSEPYIF VAHDYVPVMP TTVAHMKKRL
510 520 530 540 550
KQYGFDDIRA DRTGYYIIFR DSHYGRDEAG KCYNSANDTA FFTYSMVMEL
560 570 580 590 600
HLFGTVGTSS KTSEDHRRHS YSSEKRPPPE HRQRDDQDRR RRDEEADIEE
610 620 630 640 650
EKKQRAKNLD PVKEAAEVIR REMTEHLLKT IRTKITLPAV FDYLNPVNHA
660 670 680 690 700
AKRRKLNIDD SHSGTIPSIV FDDSEGRSSP VGTPNSRADP IERRTARADV
710 720 730 740 750
STLRVRKLKS RGVNARKHGF NDPFARARPT QRVDLRSLHH RLNSDSDDDS
760 770 780 790 800
DDGVDNRYSM IRDTEEPESR PRSRMSSEED RNKEETGSWV AGEDDSMTEA
810 820 830 840 850
SFALNDTSAL LRKRKLDLPV ETAIKRQKKA EELFEATIAP IETQLPSKEQ
860 870 880 890 900
SVESATLPGT EAALDGLPDA DVKAEPTEDK ETDDSRLPTP QPDNTKLKKK
910 920 930 940 950
GKAKKKSKKQ IFEEREALKK QQQEIYEREA LRAAGIEDIE ATPEAEAKSK
960 970 980 990 1000
AGEPEAVPEP ELEKGEAPEA PAIESKPDLD PELYPSEPVN ALVLPKDFHL
1010 1020 1030 1040 1050
DIGTLKLVPL QGEDGPDTQR LQRKFGTGKL ECDAELWLWK RNRIRQLNSE
1060 1070 1080 1090 1100
DGSKDKPVGI GGYYVPNPTG CARTEGVKKI LNSEKSKYLP HHIKVKKARE
1110 1120 1130 1140 1150
EREKNAKNGN INSVAAAAEA ARLAADSLVA KGNSRANRVN NRRYVAEIND
1160 1170 1180 1190 1200
QRKNFGQDSD VLRFNQLKKR KKPVKFARSA IHNWGLYAME NINKDDMIIE
1210 1220 1230 1240 1250
YVGEEVRQQI AELREARYLK SGIGSSYLFR IDDNTVIDAT KKGGIARFIN
1260 1270 1280 1290 1300
HSCMPNCTAK IIKVEGSKRI VIYALRDIAQ NEELTYDYKF EREIGSTDRI
1310
PCLCGTAACK GFLN
Length:1,314
Mass (Da):145,987
Last modified:September 21, 2011 - v1
Checksum:iB8C33CC77E37A03F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABT02000007 Genomic DNA Translation: CCC08898.1
RefSeqiXP_003344526.1, XM_003344478.1

Genome annotation databases

EnsemblFungiiCCC08898; CCC08898; SMAC_07534
GeneIDi10801820
KEGGismp:SMAC_07534

Similar proteinsi

Entry informationi

Entry nameiF7VTR0_SORMK
AccessioniPrimary (citable) accession number: F7VTR0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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