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F7V7Z8

- F7V7Z8_CLOSS

UniProt

F7V7Z8 - F7V7Z8_CLOSS

Protein

Elongation factor Tu

Gene

TufB

Organism
Clostridium sp. (strain SY8519)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi82 – 865GTPUniRule annotation
    Nucleotide bindingi137 – 1404GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotation

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCSP1042156:GHDR-313-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:TufBImported
    Synonyms:tufUniRule annotationImported
    Ordered Locus Names:CXIVA_02910Imported
    OrganismiClostridium sp. (strain SY8519)Imported
    Taxonomic identifieri1042156 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000008937: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F7V7Z8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKFERSK PHCNIGTIGH VDHGKTTLTA AITKVLAARV EGNSVVDFEN    50
    IDKAPEERER GITISTAHVE YETEKRHYAH VDCPGHADYV KNMITGAAQM 100
    DGAILVVAAT DGVMAQTKEH ILLSRQVGVP YIIVFLNKCD MVDDEELIEL 150
    VEMEVTEVLE EYGFHDCPII KGSALKALED PNGEWGDKIM ELMDVVDSYI 200
    PDPQRDTDKP FLMPVEDVFT ITGRGTVATG RVERGTLHIN EEVEIVGIKE 250
    ETQKTTVTGI EMFRKLLDEA QAGDNIGALL RGIKREQIER GQVLAAPGTV 300
    TCHHKFTAQV YVLTKDEGGR HTPFFNNYRP QFYFRTTDVT GVCMLPEGTE 350
    MCMPGDNVEM TIDLIHPVAM EQGLTFAIRE GGHTVGSGRV ATIIE 395
    Length:395
    Mass (Da):43,741
    Last modified:September 21, 2011 - v1
    Checksum:i8D798C20ACBE2F76
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012212 Genomic DNA. Translation: BAK46258.1.
    RefSeqiWP_013976242.1. NC_015737.1.
    YP_004707360.1. NC_015737.1.

    Genome annotation databases

    EnsemblBacteriaiBAK46258; BAK46258; CXIVA_02910.
    GeneIDi10924244.
    KEGGicls:CXIVA_02910.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012212 Genomic DNA. Translation: BAK46258.1 .
    RefSeqi WP_013976242.1. NC_015737.1.
    YP_004707360.1. NC_015737.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAK46258 ; BAK46258 ; CXIVA_02910 .
    GeneIDi 10924244.
    KEGGi cls:CXIVA_02910.

    Phylogenomic databases

    KOi K02358.

    Enzyme and pathway databases

    BioCyci CSP1042156:GHDR-313-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genomic sequence of the O-desmethylangolensin-producing bacterium Clostridium rRNA cluster XIVa strain SY8519, isolated from adult human intestine."
      Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.
      J. Bacteriol. 193:5568-5569(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SY8519Imported.

    Entry informationi

    Entry nameiF7V7Z8_CLOSS
    AccessioniPrimary (citable) accession number: F7V7Z8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3