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F7V608 (F7V608_CLOSS) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tryptophan--tRNA ligase HAMAP-Rule MF_00140

EC=6.1.1.2 HAMAP-Rule MF_00140
Alternative name(s):
Tryptophanyl-tRNA synthetase HAMAP-Rule MF_00140
Gene names
Name:TrpS EMBL BAK48187.1
Synonyms:trpS HAMAP-Rule MF_00140
Ordered Locus Names:CXIVA_22200 EMBL BAK48187.1
OrganismClostridium sp. (strain SY8519) [Complete proteome] [HAMAP]
Taxonomic identifier1042156 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp). SAAS SAAS024109 HAMAP-Rule MF_00140

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00140

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00140.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00140

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif14 – 229"HIGH" region By similarity HAMAP-Rule MF_00140
Motif197 – 2015"KMSKS" region By similarity HAMAP-Rule MF_00140

Sites

Binding site2001ATP By similarity HAMAP-Rule MF_00140

Sequences

Sequence LengthMass (Da)Tools
F7V608 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: ADB2481E3AD05216

FASTA33437,718
        10         20         30         40         50         60 
MLNDKKVLFS AMQSTGNLTL GNYLGALKNW VALSDEYECF YSVVDMHSIT VRQNPAELRK 

        70         80         90        100        110        120 
RARALLILYI AAGLDPEKNC IYYQSHVSGH AELAWILDCF TYMGELNRMT QFKDKAAKHA 

       130        140        150        160        170        180 
DNINAGLFTY PVLMAADILL YQTDVVPVGV DQMQHLELTR DIATRFNGIY GDVFTIPEAY 

       190        200        210        220        230        240 
IGKAGARIMS LQNPEKKMSK SDENPNASIY LMDDPDTIMR KFKRAVTDSE ANICYSDAQP 

       250        260        270        280        290        300 
GVRNLLDIYC ACTQKTPDEA VAEFSGRGYG ELKTAVGETV VDLLRPLQAR VRELEQDKAY 

       310        320        330 
IDSMIKNNTE KAQYFSNKTL RKVQKKVGFP ERIR 

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References

[1]"Complete genomic sequence of the O-desmethylangolensin-producing bacterium Clostridium rRNA cluster XIVa strain SY8519, isolated from adult human intestine."
Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.
J. Bacteriol. 193:5568-5569(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SY8519.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP012212 Genomic DNA. Translation: BAK48187.1.
RefSeqYP_004709289.1. NC_015737.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK48187; BAK48187; CXIVA_22200.
GeneID10926293.
KEGGcls:CXIVA_22200.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01867.

Enzyme and pathway databases

BioCycCSP1042156:GHDR-2609-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00140_B. Trp_tRNA_synth_B.
InterProIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERPTHR10055. PTHR10055. 1 hit.
PfamPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSPR01039. TRNASYNTHTRP.
TIGRFAMsTIGR00233. trpS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF7V608_CLOSS
AccessionPrimary (citable) accession number: F7V608
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)