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F7V5C1 (F7V5C1_CLOSS) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cysteine--tRNA ligase HAMAP-Rule MF_00041
EC=6.1.1.16 HAMAP-Rule MF_00041
Alternative name(s):
Cysteinyl-tRNA synthetase HAMAP-Rule MF_00041
Gene names
Name:cysS HAMAP-Rule MF_00041
Ordered Locus Names:CXIVA_19830 EMBL BAK47950.1
OrganismClostridium sp. (strain SY8519) [Complete proteome] [HAMAP]
Taxonomic identifier1042156 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length468 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys). HAMAP-Rule MF_00041 SAAS SAAS015273

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00041

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00041

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00041 SAAS SAAS015273.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00041

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif29 – 3911"HIGH" region By similarity HAMAP-Rule MF_00041
Motif267 – 2715"KMSKS" region By similarity HAMAP-Rule MF_00041

Sites

Metal binding271Zinc By similarity HAMAP-Rule MF_00041
Metal binding2101Zinc By similarity HAMAP-Rule MF_00041
Metal binding2351Zinc By similarity HAMAP-Rule MF_00041
Metal binding2391Zinc By similarity HAMAP-Rule MF_00041
Binding site2701ATP By similarity HAMAP-Rule MF_00041

Sequences

Sequence LengthMass (Da)Tools
F7V5C1 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: E4E7C90AE5739B24

FASTA46853,951
        10         20         30         40         50         60 
MEIYNTLSRK KEEFVPLQKG RVGMYVCGPT VYNFIHIGNA RPMIVFDTVR RYLEYKGYEV 

        70         80         90        100        110        120 
NYVSNFTDVD DKIIAKSIEE GIPADQVAER YIEECKKDMA AMNIEPATTH PLATEVIPDM 

       130        140        150        160        170        180 
IQMIQDLIDK GYAYAAEDGT VYYRTRKFRD YGKLSHKNID DLEGGHRSIQ VTGEQKEDPL 

       190        200        210        220        230        240 
DFVLWKPKKD GEPYWDSPWC QGRPGWHIEC SVMSKKYIGD ELDIHAGGED LIFPHHENEI 

       250        260        270        280        290        300 
AQSEAANGVP FAKYWMHNAF LNINNKKMSK SLGNFFTVRE IAEKYDLQVL RFFMLSAHYR 

       310        320        330        340        350        360 
SPLNFSADLM DAAKSGLERI RNAADHLRHL EENAAGEMTA EEQKLYEESR KYVDKFEASM 

       370        380        390        400        410        420 
EDDFNTADAI AAIFEYVKFC NTHASETSSR GFADALYQRL IRLTDILGIL VEPEEEEFLD 

       430        440        450        460 
SDIEALIQER QEARASKNFA RADEIRDQLK ERGIILKDTR EGVTWQRA

« Hide

References

[1]"Complete genomic sequence of the O-desmethylangolensin-producing bacterium Clostridium rRNA cluster XIVa strain SY8519, isolated from adult human intestine."
Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.
J. Bacteriol. 193:5568-5569(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SY8519.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP012212 Genomic DNA. Translation: BAK47950.1.
RefSeqYP_004709052.1. NC_015737.1.

3D structure databases

ProteinModelPortalF7V5C1.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK47950; BAK47950; CXIVA_19830.
GeneID10925457.
KEGGcls:CXIVA_19830.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01883.

Enzyme and pathway databases

BioCycCSP1042156:GHDR-2031-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00041. Cys_tRNA_synth.
InterProIPR015803. Cys-tRNA-ligase.
IPR015273. Cys-tRNA-synt_Ia_DALR.
IPR024909. Cys-tRNA/MSH_ligase.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR10890. PTHR10890. 1 hit.
PfamPF09190. DALR_2. 1 hit.
PF01406. tRNA-synt_1e. 1 hit.
[Graphical view]
PRINTSPR00983. TRNASYNTHCYS.
SMARTSM00840. DALR_2. 1 hit.
[Graphical view]
SUPFAMSSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMsTIGR00435. cysS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF7V5C1_CLOSS
AccessionPrimary (citable) accession number: F7V5C1
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 29, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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