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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Halorhabdus tiamatea SARL4B
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei183GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1
Binding sitei230GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi64 – 68GTPUniRule annotation5
Nucleotide bindingi152 – 154GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseImported
Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Synonyms:ftsZ1Imported
ORF Names:HLRTI_002496Imported, HTIA_0754Imported
OrganismiHalorhabdus tiamatea SARL4BImported
Taxonomic identifieri1033806 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeHalorhabdus
Proteomesi
  • UP000015381 Componenti: Chromosome
  • UP000003861 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi1033806.HLRTI_12980

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 248TubulinInterPro annotationAdd BLAST193
Domaini250 – 367Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201 Archaea
COG0206 LUCA
KOiK03531
OrthoDBiPOG093Z0942

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

F7PMC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSIIDDAME ETDDDPEEPS VEEHDEPTDT ATEEPATSGQ MTDEELADVV
60 70 80 90 100
EDLETKITVV GAGGAGGNTV TRMMEEGIHG AKLVAANTDA QHLADEVKAD
110 120 130 140 150
TKILIGKKRT GGRGAGSVPK IGEEAAQENI EDIQQSIDGS DMVFVTAGLG
160 170 180 190 200
GGTGTGSAPV IAQAAQDAGA LTISIVTIPF TAEGERRRAN ADAGLERLRA
210 220 230 240 250
VSDTVIVVPN DRLLDYAPSM PLQDAFKICD RVLMRSVKGM TELITKPGLV
260 270 280 290 300
NVDFADVRTI MENGGVAMIG LGESDSENKA QDSIRSALRS PLLDVEFDGA
310 320 330 340 350
NSALVNVVGG PDMSIEEAEG VVEEIYDRID PDARIIWGAS VNHEHDGQME
360 370 380
TMIVVTGVES PQIYGKSEAE REKAAQRMGD DIDYVE
Length:386
Mass (Da):40,912
Last modified:September 21, 2011 - v1
Checksum:iA0CE2D1925EF1464
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HF571520 Genomic DNA Translation: CCQ32894.1
AFNT02000031 Genomic DNA Translation: ERJ05518.1
RefSeqiWP_008527238.1, NZ_AFNT02000031.1

Genome annotation databases

EnsemblBacteriaiCCQ32894; CCQ32894; HTIA_0754
ERJ05518; ERJ05518; HLRTI_002496
GeneIDi23797913
KEGGihti:HTIA_0754

Similar proteinsi

Entry informationi

Entry nameiF7PMC8_9EURY
AccessioniPrimary (citable) accession number: F7PMC8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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