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Protein
Submitted name:

Hexokinase 1

Gene

HK1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 1Imported
Gene namesi
Name:HK1Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 9

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMMUG00000011845.
ExpressionAtlasiF7H4Y8. baseline.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000015543.

Structurei

3D structure databases

ProteinModelPortaliF7H4Y8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 218Hexokinase_1InterPro annotationAdd BLAST198
Domaini224 – 458Hexokinase_2InterPro annotationAdd BLAST235
Domaini469 – 666Hexokinase_1InterPro annotationAdd BLAST198
Domaini672 – 906Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
OMAiYDDQQCE.
OrthoDBiEOG091G08MD.
TreeFamiTF314238.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
PROSITEiView protein in PROSITE
PS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.

Sequencei

Sequence statusi: Complete.

F7H4Y8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDCEHSLSLP CRGAEAWEIG IDKYLYAMRL SDETLIDIMT RFKKEMKNGL
60 70 80 90 100
SRDFNPTATV KMLPTFVRSI PDGSEKGDFI ALDLGGSSFR ILRVQVNHEK
110 120 130 140 150
NQNVHMESEV YDTPENIVHG SGSQLFDHVA ECLGDFMEKR KIKDKKLPVG
160 170 180 190 200
FTFSFPCQQS KIDEAILITW TKRFKASGVE GADVVKLLNK AIKKRGDYDA
210 220 230 240 250
NIVAVVNDTV GTMMTCGYDD QQCEVGLIIG TGTNACYMEE LRHIDLVEGD
260 270 280 290 300
EGRMCINTEW GAFGDDGSLE DIRTEFDREI DRGSLNPGKQ LFEKMVSGMY
310 320 330 340 350
LGELVRLILV KMAKEGLLFE GRITPELLTR GKFNTSDVSA IEKNKEGLHN
360 370 380 390 400
AKEILTRLGV EPSDDDCVSV QHVCTIVSFR SANLVAATLG AILNRLRDNK
410 420 430 440 450
GTPRLRTTVG VDGSLYKTHP QYSRRFHKTL RRLVPDSDVR FLLSESGSGK
460 470 480 490 500
GAAMVTAVAY RLAEQHRQIE ETLAHFHLTK DMLLEVKKRM RAEMELGLRK
510 520 530 540 550
QTHNNAVVKM LPSFVRSTPD GTENGDFLAL DLGGTNFRVL LVKIRSGKKR
560 570 580 590 600
TVEMHNKIYA IPIEIMQGTG EELFDHIVSC ISDFLDYMGI KGPRMPLGFT
610 620 630 640 650
FSFPCQQTSL DAGILITWTK GFKATDCVGH DVATLLRDAI KRREEFDLDV
660 670 680 690 700
VAVVNDTVGT MMTCAYEEPT CEVGLIVGTG SNACYMEEMK NVEMVEGDQG
710 720 730 740 750
LMCINMEWGA FGDNGRLDDI RTQYDRLVDE YSLNAGKQRY EKMISGMYLG
760 770 780 790 800
EIVRNILIDF TKKGFLFRGQ ISEPLKTRGI FETKFLSQIE SDRLALLQVR
810 820 830 840 850
AILQQLGLNS TCDDSILVKT VCGVVSRRAA QLCGAGMAAV VDKIRENRGL
860 870 880 890 900
DRLNVTVGVD GTLYKLHPHF SRIMHQTVKE LSPKCNVSFL LSEDGSGKGA
910
ALITAVGVRL RTEASS
Length:916
Mass (Da):102,092
Last modified:November 30, 2016 - v2
Checksum:i51E4DD135F314BD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03043649 Genomic DNA. No translation available.
JSUE03043650 Genomic DNA. No translation available.
JSUE03043651 Genomic DNA. No translation available.
JSUE03043652 Genomic DNA. No translation available.
JSUE03043653 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMMUT00000016593; ENSMMUP00000015543; ENSMMUG00000015302.

Similar proteinsi

Entry informationi

Entry nameiF7H4Y8_MACMU
AccessioniPrimary (citable) accession number: F7H4Y8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: August 30, 2017
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported