Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Potassium voltage-gated channel subfamily J member 14

Gene

KCNJ14

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei177Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Voltage-gated channelUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotationSAAS annotation, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel subfamily J member 14Imported
Gene namesi
Name:KCNJ14Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei86 – 112HelicalSequence analysisAdd BLAST27
Transmembranei124 – 142HelicalSequence analysisAdd BLAST19
Transmembranei162 – 186HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMMUG00000001792.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000002382.

Structurei

3D structure databases

ProteinModelPortaliF7GGT0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00760000118842.
InParanoidiF7GGT0.
KOiK05007.
OMAiFVNMSER.
OrthoDBiEOG091G08HC.
TreeFamiTF313676.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiView protein in InterPro
IPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR013518. K_chnl_inward-rec_Kir_cyto.
PANTHERiPTHR11767. PTHR11767. 1 hit.
PfamiView protein in Pfam
PF01007. IRK. 1 hit.
PIRSFiPIRSF005465. GIRK_kir. 1 hit.
PRINTSiPR01320. KIRCHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

F7GGT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLARALRRL SGALDSGDSR AGDEEEAGPG LCRNGWVPAR VQSPVGRRRG
60 70 80 90 100
RFVKKDGHCN VRFVNLGGQG ARYLSDLFTT CVDVRWRWMC LLFSCSFLAS
110 120 130 140 150
WLLFGLAFWL IASLHGDLAA PPPPAPCFSH VASFLAAFLF ALETQTSIGY
160 170 180 190 200
GVRSVTEECP AAVAAVVLQC IAGCVLDAFV VGAVMAKMAK PKKRNETLVF
210 220 230 240 250
SENAVVALRD HRLCLMWRVG NLRRSHLVEA HVRAQLLQPR VTPEGEYIPL
260 270 280 290 300
DHQDVDVGFD GGTDRIFLVS PITIVHEIDS ASPLYELGRA ELARADFELV
310 320 330 340 350
VILEGMVEAT AMTTQCRSSY LPGELLWGHR FEPVLFQRGS QYEVDYRHFH
360 370 380 390 400
RTYEVPGTPV CSAKELDERA EQASHSLKSS FPGSLTAFCY ENELALSCCQ
410 420 430
EEDEDDEAEE GNGAETEDGA ASPRVLTPTL ALTLPL
Length:436
Mass (Da):47,891
Last modified:July 27, 2011 - v1
Checksum:i8EBFDF4354B0311C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03022062 Genomic DNA. No translation available.
RefSeqiXP_014979951.1. XM_015124465.1.
UniGeneiMmu.25453.

Genome annotation databases

EnsembliENSMMUT00000002519; ENSMMUP00000002382; ENSMMUG00000001792.
GeneIDi718011.
KEGGimcc:718011.

Similar proteinsi

Entry informationi

Entry nameiF7GGT0_MACMU
AccessioniPrimary (citable) accession number: F7GGT0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: January 31, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported