Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

F7GBF5 (F7GBF5_MACMU) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length1229 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMMUP00000021637

Ontologies

Keywords
   Molecular functionHydrolase SAAS SAAS023801
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processHsp90 deacetylation

Inferred from electronic annotation. Source: Ensembl

aggresome assembly

Inferred from electronic annotation. Source: Ensembl

cellular response to hydrogen peroxide

Inferred from electronic annotation. Source: Ensembl

cellular response to misfolded protein

Inferred from electronic annotation. Source: Ensembl

lysosome localization

Inferred from electronic annotation. Source: Ensembl

macroautophagy

Inferred from electronic annotation. Source: Ensembl

misfolded or incompletely synthesized protein catabolic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of microtubule depolymerization

Inferred from electronic annotation. Source: Ensembl

negative regulation of proteolysis

Inferred from electronic annotation. Source: Ensembl

peptidyl-lysine deacetylation

Inferred from electronic annotation. Source: Ensembl

polyubiquitinated misfolded protein transport

Inferred from electronic annotation. Source: Ensembl

positive regulation of chaperone-mediated protein complex assembly

Inferred from electronic annotation. Source: Ensembl

positive regulation of epithelial cell migration

Inferred from electronic annotation. Source: Ensembl

positive regulation of hydrogen peroxide-mediated programmed cell death

Inferred from electronic annotation. Source: Ensembl

positive regulation of receptor biosynthetic process

Inferred from electronic annotation. Source: Ensembl

positive regulation of signal transduction

Inferred from electronic annotation. Source: Ensembl

protein complex disassembly

Inferred from electronic annotation. Source: Ensembl

protein polyubiquitination

Inferred from electronic annotation. Source: Ensembl

regulation of establishment of protein localization

Inferred from electronic annotation. Source: Ensembl

regulation of receptor activity

Inferred from electronic annotation. Source: Ensembl

response to growth factor

Inferred from electronic annotation. Source: Ensembl

response to toxic substance

Inferred from electronic annotation. Source: Ensembl

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentaggresome

Inferred from electronic annotation. Source: Ensembl

caveola

Inferred from electronic annotation. Source: Ensembl

cell leading edge

Inferred from electronic annotation. Source: Ensembl

cytoplasmic microtubule

Inferred from electronic annotation. Source: Ensembl

cytosol

Inferred from electronic annotation. Source: Ensembl

dynein complex

Inferred from electronic annotation. Source: Ensembl

histone deacetylase complex

Inferred from electronic annotation. Source: Ensembl

perinuclear region of cytoplasm

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionhistone deacetylase activity

Inferred from electronic annotation. Source: Ensembl

tubulin deacetylase activity

Inferred from electronic annotation. Source: Ensembl

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F7GBF5 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 65D90AAC97408AEC

FASTA1,229132,829
        10         20         30         40         50         60 
MRGGNRGRGQ ASSTMTSTGQ DSTTTRQRRS RQNPQSPPQD SSVTSKRNIK KGAVPRSIPN 

        70         80         90        100        110        120 
LAEVKKKGKM KKLGQAMEED LIAGLQGMDL NLEAEALAGT GLVLDEQLNE FHCLWDDSFP 

       130        140        150        160        170        180 
EGPERLHAIK EQLIQEGLLD RCVSFQARFA EKEELMLVHS LEYIDLMETT QYMNEGELRV 

       190        200        210        220        230        240 
LADTYDSVYL HPNSYSCACL ASGSVLRLVD AVLGAEIRNG MAIIRPPGHH AQHSLMDGYC 

       250        260        270        280        290        300 
MFNHVAVAAR YAQQKHRIRR VLIVDWDVHH GQGTQFTFDQ DPSVLYFSIH RYEQGRFWPH 

       310        320        330        340        350        360 
LKASNWSTTG FGQGQGYTIN VPWNQVGMRD ADYIAAFLHV LLPVALEFQP QLVLVAAGFD 

       370        380        390        400        410        420 
ALQGDPKGEM AATPAGFAQL THLLMGLAGG KLILSLEGGY NLRALAEGVS ASLHTLLGDP 

       430        440        450        460        470        480 
CPMLESPGAP CRSAQASVSC ALEALEPFWE VLVRSTETVE GDNMEEDNVE ENEEEGPWEP 

       490        500        510        520        530        540 
PVLPILTWPV LQSRTGLVYD QSMMNHCNLW DSHHPEVPQR ILRIMCRLEE LGLAGRCLTL 

       550        560        570        580        590        600 
TPRPATEAEL LTCHSAEYVG HLRATEKMKT RELHRESSNF DSIYICPSTF ACAQLATGAA 

       610        620        630        640        650        660 
CRLVEAVLSG EVLNGAAVVR PPGHHAEQDA ACGFCFFNSV AVAARHAQAI SGRALRILIV 

       670        680        690        700        710        720 
DWDVHHGNGT QHMFEDDPSV LYVSLHRYDH GTFFPMGDEG ASSQIGRAAG TGFTVNVAWN 

       730        740        750        760        770        780 
GPRMGDADYL AAWHRLVLPI AYEFNPELVL VSAGFDAARG DPLGGCQVSP EGYAHLTHLL 

       790        800        810        820        830        840 
MGLASGRIIL ILEGGYNLTS ISESMAACTR SLLGDPPPLL TLPRPPLSGA LASITETIQV 

       850        860        870        880        890        900 
HRRYWRSLRV MKVEDREGPS SSKLVTKKAP QPAKPRLAER MTTREKKVLE AGMGKITSAS 

       910        920        930        940        950        960 
SGEESTPGQT KSETAVVALT QDQSSEAATG GATLAQTISE AAVGGAMLGQ TTSEEAVGGA 

       970        980        990       1000       1010       1020 
TPDQTTSEKT VGGATLDQTT SEDAVGGATL GQTTSEEAVG GATLAQTTSE AAMEGATLDQ 

      1030       1040       1050       1060       1070       1080 
TTSEEAPGGT ELIQTPLASS TDHQTPPTSP VQGTTPQISP STLIENLRTL ELGSKSQGAS 

      1090       1100       1110       1120       1130       1140 
ESQAPGEENL LGEAAGGQDM ADSMLMQGSR GLTDQAIFYA VTPLPWCPHL VAVCPIPAAG 

      1150       1160       1170       1180       1190       1200 
LDVTQPCGDC GTIQENWVCL SCYQVYCGRY INGHMLQHHE NSGHPLVLSY IDLSTWCYYC 

      1210       1220 
QAYVHHQALL DVKNIAHQNK FGEDMPHPH 

« Hide

References

« Hide 'large scale' references
[1]"Evolutionary and biomedical insights from the rhesus macaque genome."
Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A. expand/collapse author list , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 17573 Ensembl ENSMMUP00000021637.
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: 17573 Ensembl ENSMMUP00000021637.

Cross-references

Sequence databases

RefSeqXP_001101619.1. XM_001101619.2.
UniGeneMmu.18720.

3D structure databases

ProteinModelPortalF7GBF5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMMUT00000023129; ENSMMUP00000021637; ENSMMUG00000016465.
GeneID711363.
KEGGmcc:711363.

Organism-specific databases

CTD10013.

Phylogenomic databases

GeneTreeENSGT00530000062809.
KOK11407.
OMALQENWVC.
OrthoDBEOG7992PT.
TreeFamTF106173.

Family and domain databases

Gene3D3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERPTHR10625. PTHR10625. 1 hit.
PfamPF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSPR01270. HDASUPER.
SMARTSM00290. ZnF_UBP. 1 hit.
[Graphical view]
PROSITEPS50271. ZF_UBP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio19972529.

Entry information

Entry nameF7GBF5_MACMU
AccessionPrimary (citable) accession number: F7GBF5
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 16, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)