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Protein
Submitted name:

Sialidase-1

Gene

NEU1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: Ensembl

GO - Biological processi

  1. oligosaccharide catabolic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase-1Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:NEU1Imported
ORF Names:EGK_14733Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
ProteomesiUP000006718 Componenti: Chromosome 4

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. lysosome Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiF7EZS0. baseline.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00720000108878.
InParanoidiF7EZS0.
KOiK01186.
OMAiGTEMFAP.
OrthoDBiEOG779NXT.
TreeFamiTF331063.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

F7EZS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGERPGTAL RGRRWGPRIL GFWGSCRVRV FATIFLLLLS LADSWSRAEN
60 70 80 90 100
DFGLVQPLVT MEQLLWVSGR QIGSVDTFRI PLITATPRGT LLAFAEARKM
110 120 130 140 150
SSSDEGAKFI ALRRSMDQGS TWSPTAFIVN DGDVPDGLNL GAVVSDVETG
160 170 180 190 200
VVFLFYSLCA HKAGCQVAST MLVWSKDDGV SWSTPRNLSL DIGTEVFAPG
210 220 230 240 250
PGSGIQKQRE PRKGRLIVCG HGTLERDGVF CLLSDDHGAS WRYGSGVSGI
260 270 280 290 300
PYGQPKREND FNPDECQPYE LPDGSVVINA RNQNNYHCHC RIVLRSYDAC
310 320 330 340 350
DTLRPRDVTF DPELVDPVVA AGAVVTSSGI VFFSNPAHPE FRVNLTLRWS
360 370 380 390 400
FSNGTSWRKE TVQLWPGPSG YSSLATLEGT MDGEEQAPQL YVLYEKGRNH
410
YTESISMAKI SVYGTL
Length:416
Mass (Da):45,728
Last modified:July 27, 2011 - v1
Checksum:i4B6A3A67DB159FEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JU334658 mRNA. Translation: AFE78411.1.
CM001256 Genomic DNA. Translation: EHH18182.1.
RefSeqiNP_001253227.1. NM_001266298.1.
UniGeneiMmu.1002.

Genome annotation databases

EnsembliENSMMUT00000030544; ENSMMUP00000028585; ENSMMUG00000021707.
GeneIDi716740.
KEGGimcc:716740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JU334658 mRNA. Translation: AFE78411.1.
CM001256 Genomic DNA. Translation: EHH18182.1.
RefSeqiNP_001253227.1. NM_001266298.1.
UniGeneiMmu.1002.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000030544; ENSMMUP00000028585; ENSMMUG00000021707.
GeneIDi716740.
KEGGimcc:716740.

Organism-specific databases

CTDi4758.

Phylogenomic databases

GeneTreeiENSGT00720000108878.
InParanoidiF7EZS0.
KOiK01186.
OMAiGTEMFAP.
OrthoDBiEOG779NXT.
TreeFamiTF331063.

Miscellaneous databases

NextBioi19986577.

Gene expression databases

ExpressionAtlasiF7EZS0. baseline.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary and biomedical insights from the rhesus macaque genome."
    Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
    , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
    Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 17573Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CR-5Imported.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: 17573Imported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CaudateImported.

Entry informationi

Entry nameiF7EZS0_MACMU
AccessioniPrimary (citable) accession number: F7EZS0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 1, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.