Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transcriptional enhancer factor TEF-5

Gene

Tead3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 39TEAPROSITE-ProRule annotationAdd BLAST39

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression
R-RNO-8951671 RUNX3 regulates YAP1-mediated transcription

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional enhancer factor TEF-5UniRule annotation
Gene namesi
Name:Tead3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1311583 Tead3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiF7EPU7

Expressioni

Gene expression databases

BgeeiENSRNOG00000000506

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000000607

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 39TEAInterPro annotationAdd BLAST39

Phylogenomic databases

eggNOGiKOG3841 Eukaryota
ENOG410XQMP LUCA
GeneTreeiENSGT00390000008670
HOVERGENiHBG056905
InParanoidiF7EPU7
OMAiSAFMEVQ
OrthoDBiEOG091G08YE

Family and domain databases

Gene3Di1.10.10.1610, 1 hit
InterProiView protein in InterPro
IPR000818 TEA/ATTS_dom
IPR038096 TEA/ATTS_sf
IPR027253 TEF-5
IPR016361 TEF_metazoa
PfamiView protein in Pfam
PF01285 TEA, 1 hit
PIRSFiPIRSF002603 TEF, 1 hit
PIRSF500720 TEF-5, 1 hit
PRINTSiPR00065 TEADOMAIN
SMARTiView protein in SMART
SM00426 TEA, 1 hit
PROSITEiView protein in PROSITE
PS00554 TEA_1, 1 hit
PS51088 TEA_2, 1 hit

Sequencei

Sequence statusi: Complete.

F7EPU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYGRNELIAR YIKLRTGKTR TRKQVSSHIQ VLARKKVREY QVGIKAMNLD
60 70 80 90 100
QVSKDKALQS MASMSSAQIV SASVLQNKFS PPSPLPQAVF STSRFWSSPP
110 120 130 140 150
LLGQQPGPSQ DIKPFAQPAY PIQPPLPPTL NSYESLAPLP PAAATAASVP
160 170 180 190 200
AWQDRTIASS RLRLLEYSAF MEVQRDPDTY SKHLFVHIGQ TNPAFSDPPL
210 220 230 240 250
EAVDVRQIYD KFPEKKGGLK ELYEKGPPNA FFLVKFWADL NSTIQEGPGA
260 270 280 290 300
FYGVSSQYSS ADSMTISVST KVCSFGKQVV EKVETEYARL ENGRFVYRIH
310 320 330 340 350
RSPMCEYMIN FIHKLKHLPE KYMMNSVLEN FTILQVVTSR DSQETLLVIA
360 370
FVFEVSTSEH GAQHHVYKLV KD
Length:372
Mass (Da):41,856
Last modified:July 22, 2015 - v2
Checksum:i61379A152FBB4906
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106225 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000000607; ENSRNOP00000000607; ENSRNOG00000000506

Similar proteinsi

Entry informationi

Entry nameiF7EPU7_RAT
AccessioniPrimary (citable) accession number: F7EPU7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: July 22, 2015
Last modified: May 23, 2018
This is version 39 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health