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Protein
Submitted name:

Arachidonate 15-lipoxygenase

Gene

ALOX15

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Fe cationUniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDioxygenaseUniRule annotationSAAS annotation, Oxidoreductase
LigandIronUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Arachidonate 15-lipoxygenaseImported
Gene namesi
Name:ALOX15Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMMUG00000030381.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000035389.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 114PLATInterPro annotationAdd BLAST113
Domaini114 – 662LipoxygenaseInterPro annotationAdd BLAST549

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili623 – 643Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the lipoxygenase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IKAN. Eukaryota.
ENOG410YN4N. LUCA.
GeneTreeiENSGT00550000074415.
InParanoidiF7EPQ4.
KOiK00460.
OMAiLTCWKDL.
OrthoDBiEOG091G04A4.
TreeFamiTF105320.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
InterProiView protein in InterPro
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR036226. LipOase_C_sf.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001885. LipOase_mml.
IPR001024. PLAT/LH2_dom.
IPR036392. PLAT/LH2_dom_sf.
PANTHERiPTHR11771. PTHR11771. 1 hit.
PfamiView protein in Pfam
PF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
PRINTSiPR00087. LIPOXYGENASE.
PR00467. MAMLPOXGNASE.
SMARTiView protein in SMART
SM00308. LH2. 1 hit.
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiView protein in PROSITE
PS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.

Sequencei

Sequence statusi: Complete.

F7EPQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLYRIRLST GASLHAGSKN QVQLWLVGQH GEAVLGKRLW PARGKETEVK
60 70 80 90 100
VEVPEYLGPL LFVKLRKRHL LQDDAWFCNW ISVQGPGDGD EVRFPCYRWV
110 120 130 140 150
EGDGVLSLPE GTGRTVGEDP QGLFQKHREE ELEERRKLYR WGNWKDGLIL
160 170 180 190 200
NVAGTKLSDL PVDERFLEDK RVDFEASLAK GLADLAIKDS LNVLTRWKDL
210 220 230 240 250
DDFKRIFWCG QSKLAERVRD SWKEDALFGY QFLNGANPML LRRSAHLPAR
260 270 280 290 300
LVFPPGMEEL QAQLEKELEG GTLFEADFSL LDGIKANVIL CSQQYLAAPL
310 320 330 340 350
VMLKLQPDGK LLPMVIQLQL PSAGSPPPPL FLPTDPPMVW LLAKCWVRSS
360 370 380 390 400
DFQLHELQSH LLRGHLMAEV IAVATMRCLP SIHPIFKLII PHLRYTLEIN
410 420 430 440 450
VRARTGLVSD MGVFDQVVST GGGGHVELLR RAGGFLTYSS FCPPDDLADR
460 470 480 490 500
GLLGVKSSFY AQDALRLWEI IFRYVEGIVS LHYKTDVAVK DDPELQTWCR
510 520 530 540 550
EITEIGLQGG QDRGFPVSLQ SRDQVCHFVT MCIFTCTGQH SSVHLGQLDW
560 570 580 590 600
YTWVPNAPCT MRLPPPTTKD ATLETVMATL PNFHQASLQM SITWQLGRRQ
610 620 630 640 650
PIMVAVGQHE EEYFSGPEPK AVLKKFREEL AALDKEIENR NAKLDMPYEY
660
LRPSLVENSV AI
Length:662
Mass (Da):74,827
Last modified:July 27, 2011 - v1
Checksum:iD90C5E1317F38650
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03015858 Genomic DNA. No translation available.
RefSeqiXP_001094627.1. XM_001094627.3.
UniGeneiMmu.26178.

Genome annotation databases

EnsembliENSMMUT00000042388; ENSMMUP00000035389; ENSMMUG00000030381.
GeneIDi709212.
KEGGimcc:709212.

Similar proteinsi

Entry informationi

Entry nameiF7EPQ4_MACMU
AccessioniPrimary (citable) accession number: F7EPQ4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: January 31, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported