F7ELD6 (F7ELD6_MACMU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu RuleBase RU004061

Gene names

Name:	TUFM EMBL AFE79951.1 Ensembl ENSMMUP00000004400
ORF Names:	EGK_12638 EMBL EHH31545.1

Organism

Macaca mulatta (Rhesus macaque) [Reference proteome] Ensembl ENSMMUP00000004400

Taxonomic identifier

9544 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Cercopithecoidea › Cercopithecidae › Cercopithecinae › Macaca

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	GTP-binding RuleBase RU000323 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325 EMBL AFE79951.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	mitochondrial nucleoid Inferred from electronic annotation. Source: Compara
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F7ELD6 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: 9570CF1BADF17199	FASTA	455	49,947
	10 20 30 40 50 60 MTTMAAATLL RATPHFSGLA TGRTFLLQGL LRPLKTPALP LLCRGLAVEA KKTYVRDKPH 70 80 90 100 110 120 VNVGTIGHVD HGKTTLTAAI TKILAEGGGA KFKKYEEIDN APEERARGIT INAAHVEYST 130 140 150 160 170 180 AARHYAHTDC PGHADYVKNM ITGTAPLDGC ILVVAANDGP MPQTREHLLL ARQIGVEHVV 190 200 210 220 230 240 VYVNKADAVQ DSEMVELVEL EIRELLTEFG YKGEETPVIV GSALCALEGR DPELGLKSVQ 250 260 270 280 290 300 KLLDAVDTYI PVPTRDLEKP FLLPVEGVFS VPGRGTVVTG TLERGILKKG DECELLGHSK 310 320 330 340 350 360 NIRTVVTGIE MFHKNLERAE AGDNLGALVR GLKREDLRRG LVMVKPGSIK PHQKVEAQVY 370 380 390 400 410 420 ILSKEEGGRH KPFVSHFMPI MFSLTWDMAC RVILPPEKEL AMPGEDLKFN LILRQPMILE 430 440 450 KGQRFTLRDG NRTIGTGLVT DTLAMTEEEK NIKWG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary and biomedical insights from the rhesus macaque genome." Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A. , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S. Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 17573 Ensembl ENSMMUP00000004400.
[2]	"Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques." Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q., Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z., Thompson J.R., Meng Y., Bai Y. , Wang J., Zhuo M., Wang T., Huang Y., Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X., Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W., Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J. Nat. Biotechnol. 29:1019-1023(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CR-5 EMBL EHH31545.1.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: 17573 Ensembl ENSMMUP00000004400.
[4]	"De novo assembly of the rhesus macaque transcriptome from NextGen mRNA sequences." Pandey S., Maudhoo M.D., Guda C., Ferguson B., Fox H., Norgren R.B. Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Caudate EMBL AFE79951.1.
[5]	"De novo assembly of the rhesus macaque transcriptome from NextGen mRNA sequences." Pandey S., Maudhoo M.D., Guda C., Ferguson B., Fox H., Norgren R.B. Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AFI38206.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	JU336198 mRNA. Translation: AFE79951.1. JV048135 mRNA. Translation: AFI38206.1. CM001272 Genomic DNA. Translation: EHH31545.1.
RefSeq	NP_001253013.1. NM_001266084.1.
UniGene	Mmu.9674.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMMUT00000004666; ENSMMUP00000004400; ENSMMUG00000003303.
GeneID	705462.
KEGG	mcc:705462.
Organism-specific databases
CTD	7284.
Phylogenomic databases
GeneTree	ENSGT00550000074682.
KO	K02358.
OMA	CEFVGYN.
Family and domain databases
InterPro	IPR000795. EF_GTP-bd_dom. IPR027417. P-loop_NTPase. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
PANTHER	PTHR23115:SF31. PTHR23115:SF31. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF52540. SSF52540. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	19983712.

Entry information

Entry name

F7ELD6_MACMU

Accession

Primary (citable) accession number: F7ELD6

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	May 29, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)