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Protein

Elongation factor Tu

Gene

TUFM

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Gene namesi
Name:TUFMImported
ORF Names:EGK_12638Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 20

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMMUG00000003303

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000004400

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 254Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0460 Eukaryota
COG0050 LUCA
GeneTreeiENSGT00550000074682
KOiK02358
OMAiYGHIDCP
OrthoDBiEOG091G0BFD
TreeFamiTF300432

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

F7ELD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTMAAATLL RATPHFSGLA TGRTFLLQGL LRPLKTPALP LLCRGLAVEA
60 70 80 90 100
KKTYVRDKPH VNVGTIGHVD HGKTTLTAAI TKILAEGGGA KFKKYEEIDN
110 120 130 140 150
APEERARGIT INAAHVEYST AARHYAHTDC PGHADYVKNM ITGTAPLDGC
160 170 180 190 200
ILVVAANDGP MPQTREHLLL ARQIGVEHVV VYVNKADAVQ DSEMVELVEL
210 220 230 240 250
EIRELLTEFG YKGEETPVIV GSALCALEGR DPELGLKSVQ KLLDAVDTYI
260 270 280 290 300
PVPTRDLEKP FLLPVEGVFS VPGRGTVVTG TLERGILKKG DECELLGHSK
310 320 330 340 350
NIRTVVTGIE MFHKNLERAE AGDNLGALVR GLKREDLRRG LVMVKPGSIK
360 370 380 390 400
PHQKVEAQVY ILSKEEGGRH KPFVSHFMPI MFSLTWDMAC RVILPPEKEL
410 420 430 440 450
AMPGEDLKFN LILRQPMILE KGQRFTLRDG NRTIGTGLVT DTLAMTEEEK

NIKWG
Length:455
Mass (Da):49,947
Last modified:July 27, 2011 - v1
Checksum:i9570CF1BADF17199
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03026008 Genomic DNA No translation available.
JU336198 mRNA Translation: AFE79951.1
JV048135 mRNA Translation: AFI38206.1
CM001272 Genomic DNA Translation: EHH31545.1
RefSeqiNP_001253013.1, NM_001266084.1
UniGeneiMmu.9674

Genome annotation databases

EnsembliENSMMUT00000004666; ENSMMUP00000004400; ENSMMUG00000003303
GeneIDi705462
KEGGimcc:705462

Similar proteinsi

Entry informationi

Entry nameiF7ELD6_MACMU
AccessioniPrimary (citable) accession number: F7ELD6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported