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F7D3L5

- F7D3L5_MACMU

UniProt

F7D3L5 - F7D3L5_MACMU

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Protein
Submitted name:

Coagulation factor XIII A chain

Gene
F13A1, EGK_14442
Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei315 – 3151 By similarityUniRule annotation
Active sitei374 – 3741 By similarityUniRule annotation
Active sitei397 – 3971 By similarityUniRule annotation
Metal bindingi437 – 4371Calcium By similarityUniRule annotation
Metal bindingi439 – 4391Calcium By similarityUniRule annotation
Metal bindingi486 – 4861Calcium By similarityUniRule annotation
Metal bindingi491 – 4911Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. blood coagulation Source: Ensembl
  2. peptide cross-linking Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII A chainImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:F13A1Imported
ORF Names:EGK_14442Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
ProteomesiUP000006718: Chromosome 4

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115156.
KOiK03917.
OMAiCEEDAVY.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F7D3L5-1 [UniParc]FASTAAdd to Basket

« Hide

MSETSRIAFG GRRAVPPNNS NAAEDDLPTL ELQGVVPRGV NLQEFLNVTS    50
IHLFKERWDT NKVDHHTDKY ENNKLIVRRG QSFYIQIDFN RPYDPRRDLF 100
RVEYVIGRYP QENKGTYIPV PIVSELQSGK WGAKIVMRED RSVRLSVQSS 150
PECIVGKFRM YVAVWTPYGI IRTSRNPETD TYILFNPWCE DDAVYLDNEK 200
EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL YVMDRAQMDL 250
SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL 300
LEYQSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ 350
MDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP 400
QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL IYITAKKDGT 450
HVVENVDATH IGKLIVTKQI GGDGMMDITD TYKFQEGQEE ERLALETALM 500
YGAKKPLNTE GVMKSRSKVD MDFEVENAVL GKDLKLTITF RNNSHNHYTI 550
TAYLSANITF YTGVSKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL 600
EQASLHFFVT ARINETRDVL AKQKSTVLTI PKLIIKVRGA QVVGSDMIVT 650
VEFTNPLKET LRNVWIHLDG PGITRPMRKM FREIRPNSTV QWEEVCRPWV 700
SGPRKLIASM SSDSLRHVYG ELDVQIQRRP SM 732
Length:732
Mass (Da):83,284
Last modified:July 27, 2011 - v1
Checksum:iED12B3C293230635
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM001256 Genomic DNA. Translation: EHH17929.1.
RefSeqiXP_001096779.2. XM_001096779.2.
UniGeneiMmu.3873.

Genome annotation databases

EnsembliENSMMUT00000001770; ENSMMUP00000001668; ENSMMUG00000001248.
GeneIDi711264.
KEGGimcc:711264.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM001256 Genomic DNA. Translation: EHH17929.1 .
RefSeqi XP_001096779.2. XM_001096779.2.
UniGenei Mmu.3873.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMMUT00000001770 ; ENSMMUP00000001668 ; ENSMMUG00000001248 .
GeneIDi 711264.
KEGGi mcc:711264.

Organism-specific databases

CTDi 2162.

Phylogenomic databases

GeneTreei ENSGT00740000115156.
KOi K03917.
OMAi CEEDAVY.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Miscellaneous databases

NextBioi 19978036.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary and biomedical insights from the rhesus macaque genome."
    Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
    , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
    Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 17573Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CR-5Imported.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: 17573Imported.

Entry informationi

Entry nameiF7D3L5_MACMU
AccessioniPrimary (citable) accession number: F7D3L5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 3, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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