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F7D3L5

- F7D3L5_MACMU

UniProt

F7D3L5 - F7D3L5_MACMU

Protein
Submitted name:

Coagulation factor XIII A chain

Gene

F13A1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei315 – 3151UniRule annotation
    Active sitei374 – 3741UniRule annotation
    Active sitei397 – 3971UniRule annotation
    Metal bindingi437 – 4371Calcium
    Metal bindingi439 – 4391Calcium
    Metal bindingi486 – 4861Calcium
    Metal bindingi491 – 4911Calcium

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. blood coagulation Source: Ensembl
    2. peptide cross-linking Source: Ensembl

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Coagulation factor XIII A chainImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:F13A1Imported
    ORF Names:EGK_14442Imported
    OrganismiMacaca mulatta (Rhesus macaque)Imported
    Taxonomic identifieri9544 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
    ProteomesiUP000006718: Chromosome 4

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115156.
    KOiK03917.
    OMAiCEEDAVY.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F7D3L5-1 [UniParc]FASTAAdd to Basket

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    MSETSRIAFG GRRAVPPNNS NAAEDDLPTL ELQGVVPRGV NLQEFLNVTS    50
    IHLFKERWDT NKVDHHTDKY ENNKLIVRRG QSFYIQIDFN RPYDPRRDLF 100
    RVEYVIGRYP QENKGTYIPV PIVSELQSGK WGAKIVMRED RSVRLSVQSS 150
    PECIVGKFRM YVAVWTPYGI IRTSRNPETD TYILFNPWCE DDAVYLDNEK 200
    EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL YVMDRAQMDL 250
    SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL 300
    LEYQSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ 350
    MDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP 400
    QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL IYITAKKDGT 450
    HVVENVDATH IGKLIVTKQI GGDGMMDITD TYKFQEGQEE ERLALETALM 500
    YGAKKPLNTE GVMKSRSKVD MDFEVENAVL GKDLKLTITF RNNSHNHYTI 550
    TAYLSANITF YTGVSKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL 600
    EQASLHFFVT ARINETRDVL AKQKSTVLTI PKLIIKVRGA QVVGSDMIVT 650
    VEFTNPLKET LRNVWIHLDG PGITRPMRKM FREIRPNSTV QWEEVCRPWV 700
    SGPRKLIASM SSDSLRHVYG ELDVQIQRRP SM 732
    Length:732
    Mass (Da):83,284
    Last modified:July 27, 2011 - v1
    Checksum:iED12B3C293230635
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM001256 Genomic DNA. Translation: EHH17929.1.
    RefSeqiXP_001096779.2. XM_001096779.2.
    UniGeneiMmu.3873.

    Genome annotation databases

    EnsembliENSMMUT00000001770; ENSMMUP00000001668; ENSMMUG00000001248.
    GeneIDi711264.
    KEGGimcc:711264.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM001256 Genomic DNA. Translation: EHH17929.1 .
    RefSeqi XP_001096779.2. XM_001096779.2.
    UniGenei Mmu.3873.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMMUT00000001770 ; ENSMMUP00000001668 ; ENSMMUG00000001248 .
    GeneIDi 711264.
    KEGGi mcc:711264.

    Organism-specific databases

    CTDi 2162.

    Phylogenomic databases

    GeneTreei ENSGT00740000115156.
    KOi K03917.
    OMAi CEEDAVY.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Miscellaneous databases

    NextBioi 19978036.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolutionary and biomedical insights from the rhesus macaque genome."
      Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
      , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
      Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 17573Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CR-5Imported.
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: 17573Imported.

    Entry informationi

    Entry nameiF7D3L5_MACMU
    AccessioniPrimary (citable) accession number: F7D3L5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3