F7CIV3 (F7CIV3_MACMU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSMMUP00000010271

Gene names

Name:

TGM3 Ensembl ENSMMUP00000010271

Organism

Macaca mulatta (Rhesus macaque) [Reference proteome] Ensembl ENSMMUP00000010271

Taxonomic identifier

9544 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Cercopithecoidea › Cercopithecidae › Cercopithecinae › Macaca

Protein attributes

Sequence length	693 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMMUP00000010271

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell envelope organization Inferred from electronic annotation. Source: Compara keratinocyte differentiation Inferred from electronic annotation. Source: Compara peptide cross-linking Inferred from electronic annotation. Source: Compara protein tetramerization Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara extrinsic to internal side of plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	GDP binding Inferred from electronic annotation. Source: Compara GTP binding Inferred from electronic annotation. Source: Compara GTPase activity Inferred from electronic annotation. Source: Compara calcium ion binding Inferred from electronic annotation. Source: Compara magnesium ion binding Inferred from electronic annotation. Source: Compara protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	273	1	By similarity PIRSR PIRSR000459-1
	Active site	331	1	By similarity PIRSR PIRSR000459-1
	Active site	354	1	By similarity PIRSR PIRSR000459-1
	Metal binding	394	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	396	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	444	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	449	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	F7CIV3 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: 57125F97430CBD5B	FASTA	693	76,875
	10 20 30 40 50 60 MAALGLQSIN WQTAFNRQAH HTHKFSSREL ILRRGQNFQV LMLMNKGLGS NERLEFIVST 70 80 90 100 110 120 GPYPSESAMT KAVFPLSNGS SGGWSAVLQA INGNTLTISI SSPASAPIGQ YTMALQISSQ 130 140 150 160 170 180 GGVSSVKLGT FILLFNPWLN ADSVFMGNHA EREEYVQEDA GIIYVGSTNR ISMIGWNFGQ 190 200 210 220 230 240 FEEDILSICL SILDRSLNFR RDPATDVARR NDPKYVGRVL SAMINSNDDN GVLAGNWSGT 250 260 270 280 290 300 YTGGRDPRNW NGSVEILKDW KKSGFSPVRY GQCWVFAGTL NTALRSLGIP SRVITNFSSA 310 320 330 340 350 360 HDTDRNLSVD VYYDRMGNPL DKGSDSVWNF HVWNEGWFVR SDLGPSYGGW QVLDATPQER 370 380 390 400 410 420 SQGVFQCGPA SVIGIREGDV NLNFDMPFIF AEVNADRITW LYDGTTGRQT KNSVDTRTIG 430 440 450 460 470 480 RYISTKAVGS NARMDVTDKY KYPEGSDQER RVFQKALGKL KPNASFGATS SMGLEAEERE 490 500 510 520 530 540 SSIIGKFKVT GMLAVGKEVN LVLLLKNLSS DTKTVTVNMT AWTIVYNGTL VHEVWKDSAT 550 560 570 580 590 600 MSLDPEEEAE HPVKISYAQY EKYLKSDNMI RITAVCKVPD EPGVVVERDI ILDNPTLTLE 610 620 630 640 650 660 VLDEARVRKP VNVQMLFSNP LDEPVRDCVL MVEGSGLLLG NLKIDVPTLR PKERSRVRFE 670 680 690 ILPTRSGTKQ LLADFSCNKF HAIKAMLSID VVE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary and biomedical insights from the rhesus macaque genome." Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A. , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S. Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 17573 Ensembl ENSMMUP00000010271.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: 17573 Ensembl ENSMMUP00000010271.

Cross-references

Sequence databases
RefSeq	XP_001113845.1. XM_001113845.2.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMMUT00000010950; ENSMMUP00000010271; ENSMMUG00000007819.
GeneID	716498.
KEGG	mcc:716498.
Organism-specific databases
CTD	7053.
Phylogenomic databases
GeneTree	ENSGT00690000101863.
KO	K05620.
OMA	LVHEVWK.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR013808. Transglutaminase_CS. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
PROSITE	PS00547. TRANSGLUTAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	19965979.

Entry information

Entry name

F7CIV3_MACMU

Accession

Primary (citable) accession number: F7CIV3

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	March 6, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)