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Protein
Submitted name:

ATP binding cassette subfamily B member 5

Gene

ABCB5

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi421 – 428ATPPROSITE-ProRule annotation8
Nucleotide bindingi1050 – 1057ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP binding cassette subfamily B member 5Imported
Gene namesi
Name:ABCB5Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 69HelicalSequence analysisAdd BLAST25
Transmembranei108 – 131HelicalSequence analysisAdd BLAST24
Transmembranei289 – 308HelicalSequence analysisAdd BLAST20
Transmembranei320 – 343HelicalSequence analysisAdd BLAST24
Transmembranei689 – 714HelicalSequence analysisAdd BLAST26
Transmembranei734 – 757HelicalSequence analysisAdd BLAST24
Transmembranei917 – 941HelicalSequence analysisAdd BLAST25
Transmembranei953 – 975HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000010273.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 349ABC transmembrane type-1InterPro annotationAdd BLAST301
Domaini386 – 622ABC transporterInterPro annotationAdd BLAST237
Domaini693 – 980ABC transmembrane type-1InterPro annotationAdd BLAST288
Domaini1015 – 1253ABC transporterInterPro annotationAdd BLAST239

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
GeneTreeiENSGT00530000062896.
InParanoidiF7CIT5.
KOiK05660.
OrthoDBiEOG091G0HVA.
TreeFamiTF105193.

Family and domain databases

Gene3Di1.20.1560.10. 2 hits.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

F7CIT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSEKAEEM QENYQRNGTV EEQSKLKKEA VGSIEIFRFA DGLDIILMIL
60 70 80 90 100
GILASLVNGA CLPLMSLVLG EMSDNLISGC LVQTNTTNYQ NCTQSQEKLN
110 120 130 140 150
EDMTVLTLYY VGIGVAALIF GYIQICFWII TAARQTKRIR KQFFHSVLAQ
160 170 180 190 200
DVGWFDSCDI GELNTRMTDD IDKISDGIGD KIALLFQNMS TFSIGLAVGL
210 220 230 240 250
VKGWKLTLVT LSTSPLIMAS AAACSRMVIS LTSKELSAYS KAGAVAEEVL
260 270 280 290 300
SSIRTVVAFG AQEKELQRYT QNLKDAKDFG IKRAIASKLS LGAVYFFMNG
310 320 330 340 350
TYGLAFWYGT SLILNGEPGY TIGTVLAVFF SVIHSSYCIG AAAPHFETFS
360 370 380 390 400
IARGAAFNIF QVIDKKPSID NFSTAGCKPE SIEGTVEFKN VSFHYPSRPS
410 420 430 440 450
IKILKGLNLR IKSGETVALV GPNGSGKSTV VQLLQRLYDP DDGFITVDEN
460 470 480 490 500
DIRALNVRHY REHIGVVSQE PVLFGTTISN NIKYGRDDVT DEEMERAARE
510 520 530 540 550
ANAYDFIMEF PNKFNTLVGE KGAQMSGGQK QRIAIARALV RNPKILILDE
560 570 580 590 600
ATSALDSESE SAVQAALEKA SKGRTTIVVA HRLSTIRSAD LIVTIKDGMV
610 620 630 640 650
AEKGAHAELM AKRGLYYSLV MSQDIKNADE QMESMTYSTE RKTNSLSLCS
660 670 680 690 700
VNSIKSDFTD KAEESIQSKE ISLPEVSLLK ILKLNKSEWP FVVLGTLASV
710 720 730 740 750
LNGTVHPVFS IIFAKIITMF GNKDKTTLKH DAEMYSMIFV ILGVICFVSY
760 770 780 790 800
FMQGLFYGRA GEILTMRLRH LAFKAMLYQD IAWFDEKENS TGSLTAILAI
810 820 830 840 850
DTAQIQGATG SRIGVLTQNA TNMGLSVIIS FLYGWEMTLL ILSIAPILAV
860 870 880 890 900
TGMIETAAMT GFANKDKQEL KHAGKIATEA VENIRTIVSL TREKAFEQMY
910 920 930 940 950
EEMLETQHRH TSKKAQIIGS CYAFSHAFIY FAYAAGFRFG AYLIQAGRMT
960 970 980 990 1000
PEGMFIVCTA IAYGAMAIGE TLVLAPEYSK AKSGAAHLFA LLEKKPTIDS
1010 1020 1030 1040 1050
HSQEGKKPDT CEGNLEFREV SFFYPCRPDV FILRGLSLSI EQGKTVAFVG
1060 1070 1080 1090 1100
SSGCGKSTSL QLLQRFYDPV QGQVLFDGVD AKELNVQWLR SQIAIVSQEP
1110 1120 1130 1140 1150
VLFNCSIAEN IAYGDNSRVV SLDEIKEAAN AANIHSFIEG LPEKYNTQVG
1160 1170 1180 1190 1200
LKGTQLSGGQ KQRLAIARAL LQKPKILLLD EATSALDNES EKVVQHALDK
1210 1220 1230 1240 1250
AKTGRTCLVV THRLSAIQNA DLIVVLHNGK IKEQGTHQEL LRNRDIYFKL

VNAQSVQ
Length:1,257
Mass (Da):138,248
Last modified:November 30, 2016 - v2
Checksum:i67F369B44FF026F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03028618 Genomic DNA. No translation available.
JSUE03028619 Genomic DNA. No translation available.
JSUE03028620 Genomic DNA. No translation available.
RefSeqiXP_014989383.1. XM_015133897.1.

Genome annotation databases

EnsembliENSMMUT00000010952; ENSMMUP00000010273; ENSMMUG00000007821.
GeneIDi712883.
KEGGimcc:712883.

Similar proteinsi

Entry informationi

Entry nameiF7CIT5_MACMU
AccessioniPrimary (citable) accession number: F7CIT5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: December 20, 2017
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported