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Protein

p2X purinoceptor

Gene

P2RX2

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Receptor for ATP that acts as a ligand-gated ion channel.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotation, ReceptorUniRule annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
p2X purinoceptorUniRule annotation
Gene namesi
Name:P2RX2Imported
OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
Proteomesi
  • UP000002280 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei83 – 101HelicalUniRule annotationAdd BLAST19
Transmembranei385 – 407HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMODG00000015154.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi13616.ENSMODP00000018938.

Family & Domainsi

Sequence similaritiesi

Belongs to the P2X receptor family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG410IGJK. Eukaryota.
ENOG410ZQ3M. LUCA.
GeneTreeiENSGT00390000016028.
InParanoidiF7CFM6.
KOiK05216.
OMAiDVIVHGQ.
OrthoDBiEOG091G0A2U.
TreeFamiTF328633.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiView protein in InterPro
IPR003045. P2X2_purnocptor.
IPR027309. P2X_extracellular_dom.
IPR001429. P2X_purnocptor.
PANTHERiPTHR10125. PTHR10125. 1 hit.
PfamiView protein in Pfam
PF00864. P2X_receptor. 1 hit.
PIRSFiPIRSF005713. P2X_purinoceptor. 1 hit.
PRINTSiPR01309. P2X2RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiView protein in PROSITE
PS01212. P2X_RECEPTOR. 1 hit.

Sequencei

Sequence statusi: Complete.

F7CFM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQTAPGTQG PGVGGSCAPG SAEARQGAEA PEPHFLMASP EPEAPEKERS
60 70 80 90 100
GRHMAKNCWN VFWGFWDYET PKVIVVKNRN LGFIYRTVQL LILLYFVWYV
110 120 130 140 150
FIIQKGYQDS ETGPESSVIT KVKGITKSQN KVWDVEEYVK PPEGGSVFTI
160 170 180 190 200
ITRAEITPFQ TLGTCPESIR IRNATCLSDD DCMAGEMDML GNGEKTGRCV
210 220 230 240 250
PYYYGTKKTC EVSAWCPVED GAAVSEFLGK MAPQFTILIK NSIHYPKFQF
260 270 280 290 300
SKGNIRDYDN DYLKHCTFNA DTDLYCPIFK LGFIVEQAGE NFTELAQKGG
310 320 330 340 350
VIGVIINWNC DLDLSEAKCN PKYSFRRLDP KHIQASSGYN YRFAKYYSHN
360 370 380 390 400
GTASRTLIKA YGIRIDVIVH GQAGKFSLIP TIINLATALT SIGVGSFLCD
410 420 430 440 450
WILLTFMNKN KVYSHRKFDK MVDTQDPNSE EQGPSGPRAS SQDSIPMEPK

GLAQL
Length:455
Mass (Da):50,710
Last modified:January 9, 2013 - v2
Checksum:i3A752730A66F6603
GO

Sequence databases

RefSeqiXP_007489638.1. XM_007489576.2.

Genome annotation databases

EnsembliENSMODT00000019280; ENSMODP00000018938; ENSMODG00000015154.
GeneIDi100027526.
KEGGimdo:100027526.

Similar proteinsi

Entry informationi

Entry nameiF7CFM6_MONDO
AccessioniPrimary (citable) accession number: F7CFM6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: October 25, 2017
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported