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F7BWZ9

- F7BWZ9_MACMU

UniProt

F7BWZ9 - F7BWZ9_MACMU

Protein
Submitted name:

Uncharacterized protein

Gene

PTGS2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. heme binding Source: Ensembl
    2. peroxidase activity Source: InterPro
    3. prostaglandin-endoperoxide synthase activity Source: Ensembl

    GO - Biological processi

    1. anagen Source: Ensembl
    2. brown fat cell differentiation Source: Ensembl
    3. cellular response to hypoxia Source: Ensembl
    4. cyclooxygenase pathway Source: Ensembl
    5. positive regulation of brown fat cell differentiation Source: Ensembl
    6. positive regulation of fever generation Source: Ensembl
    7. regulation of blood pressure Source: Ensembl
    8. regulation of cell proliferation Source: Ensembl
    9. response to oxidative stress Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:PTGS2Imported
    ORF Names:EGK_01845Imported
    OrganismiMacaca mulatta (Rhesus macaque)Imported
    Taxonomic identifieri9544 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
    ProteomesiUP000006718: Chromosome 1

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. neuron projection Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000010743.
    KOiK11987.
    OMAiICNNVKG.
    OrthoDBiEOG7RFTHC.
    TreeFamiTF329675.

    Family and domain databases

    Gene3Di1.10.640.10. 1 hit.
    InterProiIPR029576. COX-2.
    IPR000742. EG-like_dom.
    IPR010255. Haem_peroxidase.
    IPR019791. Haem_peroxidase_animal.
    [Graphical view]
    PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
    PfamiPF03098. An_peroxidase. 1 hit.
    [Graphical view]
    PRINTSiPR00457. ANPEROXIDASE.
    SMARTiSM00181. EGF. 1 hit.
    [Graphical view]
    SUPFAMiSSF48113. SSF48113. 1 hit.
    PROSITEiPS50026. EGF_3. 1 hit.
    PS50292. PEROXIDASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F7BWZ9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLARALLLCA VLALGHAANP CCSYPCQNRG VCMSVGFDQY KCDCTRTGFY    50
    GENCSTPEFL TRIKLLLKPT PNTVHYILTH FKGFWNVVNN IPFLRNAIMS 100
    YVLTSRSHLI DSPPTYNADY GYKSWEAFSN LSYYTRALPP VPDDCPTPLG 150
    VKGKKQLPDS NEIVEKFLLR RKFIPDPQGT NMMFAFFAQH FTHQFFKTDH 200
    KRGPAFTKGL GHGVDLNHIY GETLDRQHKL RLFKDGKMKY QIIDGEMYPP 250
    TVKDTQAEMI YPPQVPEHLR FAVGQEVFGL VPGLMMYATI WLREHNRVCD 300
    VLKQEHPEWG DEQLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE 350
    LLFNKQFQYQ NRIAAEFNTL YHWHPLLPDN FQIHDQKYNY QQFIYNNSIL 400
    LEHGITQFVE SFTRQIAGRV AGGRNVPPAV QKVSQASIDQ SRQMKYQSFN 450
    EYRKRFMLKP YESFEELTGE KEMSAELEAL YGDIDAVELY PALLVEKPRP 500
    DAIFGETMVE VGAPFSLKGL MGNVICSPAY WKPSTFGGEV GFQIINTASI 550
    QSLICNNVKG CPFTSFSVPD PELIKTVTIN ASSSRSRLDD INPTVLLKER 600
    STEL 604
    Length:604
    Mass (Da):69,127
    Last modified:July 27, 2011 - v1
    Checksum:i86029F273009CAE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM001253 Genomic DNA. Translation: EHH15717.1.
    RefSeqiXP_001107538.2. XM_001107538.2.
    UniGeneiMmu.24378.

    Genome annotation databases

    EnsembliENSMMUT00000023682; ENSMMUP00000022160; ENSMMUG00000016857.
    GeneIDi716671.
    KEGGimcc:716671.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM001253 Genomic DNA. Translation: EHH15717.1 .
    RefSeqi XP_001107538.2. XM_001107538.2.
    UniGenei Mmu.24378.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMMUT00000023682 ; ENSMMUP00000022160 ; ENSMMUG00000016857 .
    GeneIDi 716671.
    KEGGi mcc:716671.

    Organism-specific databases

    CTDi 5743.

    Phylogenomic databases

    GeneTreei ENSGT00390000010743.
    KOi K11987.
    OMAi ICNNVKG.
    OrthoDBi EOG7RFTHC.
    TreeFami TF329675.

    Miscellaneous databases

    NextBioi 19979462.

    Family and domain databases

    Gene3Di 1.10.640.10. 1 hit.
    InterProi IPR029576. COX-2.
    IPR000742. EG-like_dom.
    IPR010255. Haem_peroxidase.
    IPR019791. Haem_peroxidase_animal.
    [Graphical view ]
    PANTHERi PTHR11903:SF8. PTHR11903:SF8. 1 hit.
    Pfami PF03098. An_peroxidase. 1 hit.
    [Graphical view ]
    PRINTSi PR00457. ANPEROXIDASE.
    SMARTi SM00181. EGF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48113. SSF48113. 1 hit.
    PROSITEi PS50026. EGF_3. 1 hit.
    PS50292. PEROXIDASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolutionary and biomedical insights from the rhesus macaque genome."
      Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
      , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
      Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 17573Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CR-5Imported.
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: 17573Imported.

    Entry informationi

    Entry nameiF7BWZ9_MACMU
    AccessioniPrimary (citable) accession number: F7BWZ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3