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Protein

Actin-related protein 2/3 complex subunit 4

Gene

ARPC4

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 2/3 complex subunit 4UniRule annotation
Gene namesi
Name:ARPC4Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000051909.

Family & Domainsi

Sequence similaritiesi

Belongs to the ARPC4 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1876. Eukaryota.
ENOG4111G2F. LUCA.
GeneTreeiENSGT00390000016233.
InParanoidiF7BGP2.
OMAiFASKLWT.
OrthoDBiEOG091G0OI8.
TreeFamiTF105621.

Family and domain databases

Gene3Di3.30.1460.20. 1 hit.
InterProiView protein in InterPro
IPR034666. ARPC2/4.
IPR008384. ARPC4.
PANTHERiPTHR22629. PTHR22629. 1 hit.
PfamiView protein in Pfam
PF05856. ARPC4. 1 hit.
PIRSFiPIRSF039100. ARPC4. 1 hit.
SUPFAMiSSF69645. SSF69645. 1 hit.

Sequencei

Sequence statusi: Complete.

F7BGP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVREPGPELG TPSCSASGLW TATLRPYLSA VRATLQAALC LENFSSQVVE
60 70 80 90 100
RHNKPEVEVR SSKELLLQPV TISRNEKEKV LIEGSINSVR VSIAVKQADE
110 120 130 140 150
IEKILCHKFM RFMMMRAENF FILRRKPVEG YDISFLITNF HTEQMYKHKL
160 170 180
VDFVIHFMEE IDKEISEMKL SVNARARIVA EEFLKNF
Length:187
Mass (Da):21,592
Last modified:July 27, 2011 - v1
Checksum:i61601E3A2725F7BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFV01016542 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCJAT00000059436; ENSCJAP00000051909; ENSCJAG00000016175.

Similar proteinsi

Entry informationi

Entry nameiF7BGP2_CALJA
AccessioniPrimary (citable) accession number: F7BGP2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 7, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported