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Protein

Vacuolar protein sorting-associated protein 28 homolog

Gene

VPS28

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.UniRule annotation

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 28 homologUniRule annotation
Gene namesi
Name:VPS28Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

EndosomeUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMMUG00000020667.
ExpressionAtlasiF7BEJ5. baseline.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 120VPS28 N-terminalInterPro annotationAdd BLAST108
Domaini124 – 220VPS28 C-terminalInterPro annotationAdd BLAST97

Sequence similaritiesi

Belongs to the VPS28 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3284. Eukaryota.
ENOG4111IQ4. LUCA.
GeneTreeiENSGT00390000007486.
KOiK12184.
OMAiKYRLDCP.

Family and domain databases

InterProiView protein in InterPro
IPR037202. ESCRT_assembly_dom.
IPR007143. VPS28.
IPR017899. VPS28_C.
IPR037206. VPS28_C_sf.
IPR017898. VPS28_N.
PANTHERiPTHR12937. PTHR12937. 1 hit.
PfamiView protein in Pfam
PF03997. VPS28. 1 hit.
PIRSFiPIRSF017535. VPS28. 1 hit.
SUPFAMiSSF140111. SSF140111. 1 hit.
SSF140427. SSF140427. 1 hit.
PROSITEiView protein in PROSITE
PS51310. VPS28_C. 1 hit.
PS51313. VPS28_N. 1 hit.

Sequencei

Sequence statusi: Complete.

F7BEJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHGIPATPG IGAPGNKPEL YEEVKLYKNA REREKYDNMA ELFAVVKTMQ
60 70 80 90 100
ALEKAYIKDC VSPSEYTAAC SRLLVQYKAA FRQVQGSEIS TIDEFCRKFR
110 120 130 140 150
LDCPLAMERI KEDRPITIKD DKGNLNRCIA DVVSLFITVM DKLRLEIRAM
160 170 180 190 200
DEIQPDLREL METMHRMSHL PPDFEGRQTV SQWLQTLSGM SASDELDDSQ
210 220
VRQMLFDLES AYNAFNRFLH A
Length:221
Mass (Da):25,439
Last modified:July 27, 2011 - v1
Checksum:iB43A6BB086C02AB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03042684 Genomic DNA. No translation available.
JU320775 mRNA. Translation: AFE64531.1.
JU473270 mRNA. Translation: AFH30074.1.
JV045518 mRNA. Translation: AFI35589.1.
RefSeqiNP_001253325.1. NM_001266396.1.
XP_015001678.1. XM_015146192.1.
UniGeneiMmu.28456.

Genome annotation databases

EnsembliENSMMUT00000029069; ENSMMUP00000027197; ENSMMUG00000020667.
GeneIDi702412.
KEGGimcc:702412.

Similar proteinsi

Entry informationi

Entry nameiF7BEJ5_MACMU
AccessioniPrimary (citable) accession number: F7BEJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: October 25, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported