F7BDU9 (F7BDU9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fibroblast growth factor receptor 2 Ensembl ENSMUSP00000122856

Gene names

Name:

Fgfr2 Ensembl ENSMUSP00000122856 MGI 95523

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000122856

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	61 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000122856

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	angiogenesis Inferred from genetic interaction PubMed 16778080. Source: MGI axonogenesis Inferred from mutant phenotype PubMed 17951031. Source: MGI bone mineralization Inferred from mutant phenotype PubMed 12756187. Source: MGI branch elongation involved in salivary gland morphogenesis Inferred from mutant phenotype PubMed 15972105. Source: MGI branching involved in labyrinthine layer morphogenesis Inferred from mutant phenotype PubMed 9435295. Source: MGI branching morphogenesis of a nerve Inferred from mutant phenotype PubMed 17951031. Source: MGI bud elongation involved in lung branching Inferred from mutant phenotype PubMed 16989802. Source: MGI cell fate commitment Inferred from direct assay PubMed 15509736. Source: MGI coronal suture morphogenesis Inferred from mutant phenotype PubMed 19389359. Source: MGI embryonic digestive tract morphogenesis Inferred from mutant phenotype PubMed 16618415PubMed 21550054. Source: MGI embryonic pattern specification Inferred from mutant phenotype PubMed 16618415. Source: MGI endodermal digestive tract morphogenesis Inferred from mutant phenotype PubMed 21550054. Source: MGI epithelial cell proliferation involved in salivary gland morphogenesis Inferred from mutant phenotype PubMed 15972105. Source: MGI fibroblast growth factor receptor signaling pathway involved in mammary gland specification Inferred from mutant phenotype PubMed 16720875. Source: MGI hair follicle morphogenesis Inferred from mutant phenotype PubMed 14530295. Source: MGI lacrimal gland development Inferred from mutant phenotype PubMed 10821755. Source: MGI lateral sprouting from an epithelium Inferred from mutant phenotype PubMed 12666202. Source: MGI lens fiber cell development Inferred from genetic interaction PubMed 18455718. Source: MGI limb bud formation Inferred from mutant phenotype PubMed 10518547PubMed 9435295. Source: MGI lung alveolus development Inferred from mutant phenotype PubMed 16989802. Source: MGI lung lobe morphogenesis Inferred from mutant phenotype PubMed 16989802. Source: MGI lung-associated mesenchyme development Inferred from mutant phenotype PubMed 16989802. Source: MGI mammary gland bud formation Inferred from mutant phenotype PubMed 11782400. Source: MGI membranous septum morphogenesis Inferred from mutant phenotype PubMed 16687131. Source: MGI mesenchymal cell differentiation involved in lung development Inferred from genetic interaction PubMed 16989802. Source: MGI mesenchymal cell proliferation involved in lung development Inferred from mutant phenotype PubMed 16989802. Source: MGI midbrain development Inferred from genetic interaction PubMed 17687036. Source: MGI multicellular organism growth Inferred from mutant phenotype PubMed 16989802. Source: MGI negative regulation of cell proliferation Inferred from genetic interaction PubMed 18455718. Source: MGI negative regulation of mitosis Inferred from genetic interaction PubMed 18455718. Source: MGI negative regulation of transcription from RNA polymerase II promoter Inferred from mutant phenotype PubMed 16989802. Source: MGI neuromuscular junction development Inferred from mutant phenotype PubMed 17418794. Source: MGI odontogenesis Inferred from mutant phenotype PubMed 17951031. Source: MGI organ growth Inferred from mutant phenotype PubMed 16618415. Source: MGI otic vesicle formation Inferred from mutant phenotype PubMed 9435295. Source: MGI outflow tract septum morphogenesis Inferred from mutant phenotype PubMed 16687131. Source: MGI positive regulation of ERK1 and ERK2 cascade Inferred from genetic interaction PubMed 17202188. Source: MGI positive regulation of canonical Wnt receptor signaling pathway Inferred from mutant phenotype PubMed 16720875. Source: MGI positive regulation of cardiac muscle cell proliferation Inferred from genetic interaction PubMed 15621532. Source: MGI positive regulation of cell division Inferred from mutant phenotype PubMed 14530295. Source: MGI positive regulation of epithelial cell proliferation involved in lung morphogenesis Inferred from mutant phenotype PubMed 16989802. Source: MGI positive regulation of mesenchymal cell proliferation Inferred from genetic interaction PubMed 16540513. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from mutant phenotype PubMed 16989802. Source: MGI post-embryonic development Inferred from mutant phenotype PubMed 16989802. Source: MGI prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Inferred from mutant phenotype PubMed 17215304. Source: MGI prostate epithelial cord elongation Inferred from mutant phenotype PubMed 17215304. Source: MGI regulation of branching involved in prostate gland morphogenesis Inferred from mutant phenotype PubMed 17202188. Source: MGI regulation of cell fate commitment Inferred from mutant phenotype PubMed 16989802. Source: MGI regulation of fibroblast growth factor receptor signaling pathway Inferred from mutant phenotype PubMed 16989802. Source: MGI regulation of multicellular organism growth Inferred from mutant phenotype PubMed 9435295. Source: MGI regulation of smooth muscle cell differentiation Inferred from mutant phenotype PubMed 16989802. Source: MGI regulation of smoothened signaling pathway Inferred from mutant phenotype PubMed 16618415. Source: MGI squamous basal epithelial stem cell differentiation involved in prostate gland acinus development Inferred from mutant phenotype PubMed 17215304. Source: MGI synaptic vesicle transport Inferred from mutant phenotype PubMed 17418794. Source: MGI ureteric bud development Inferred from genetic interaction PubMed 16442091. Source: MGI ventricular cardiac muscle tissue morphogenesis Inferred from mutant phenotype PubMed 16687131. Source: MGI
Cellular_component	extracellular region Traceable author statement PubMed 12024206. Source: MGI nucleus Inferred from direct assay PubMed 15229180PubMed 15944199. Source: MGI
Molecular_function	fibroblast growth factor binding Inferred from direct assay PubMed 9435295. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSMUSP00000122856

Sequences

	Sequence		Length	Mass (Da)
	F7BDU9 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: 772EF8B8ACDDB79B	FASTA	61	6,998
	10 20 30 40 50 60 XRLHAVPAAN TVKFRCPAGG NPTPTMRWLK NGKEFKQEHR IGGYKVPREE LSQGHECQEY H

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000122856.
[2]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000122856.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC087063 Genomic DNA. No translation available. AC099609 Genomic DNA. No translation available. AC099627 Genomic DNA. No translation available. AC100735 Genomic DNA. No translation available. AC101690 Genomic DNA. No translation available. AC101762 Genomic DNA. No translation available. AC105062 Genomic DNA. No translation available. AC110885 Genomic DNA. No translation available. AC111058 Genomic DNA. No translation available. AC115697 Genomic DNA. No translation available. AC119806 Genomic DNA. No translation available. AC122258 Genomic DNA. No translation available. AC126688 Genomic DNA. No translation available. AC138624 Genomic DNA. No translation available. AC145294 Genomic DNA. No translation available. AC149596 Genomic DNA. No translation available. AC156606 Genomic DNA. No translation available. AC157606 Genomic DNA. No translation available. AC158113 Genomic DNA. No translation available. AC158314 Genomic DNA. No translation available. AC159994 Genomic DNA. No translation available. AC175034 Genomic DNA. No translation available. AC238818 Genomic DNA. No translation available.
IPI	IPI00894615.
3D structure databases
ProteinModelPortal	F7BDU9.
SMR	F7BDU9. Positions 2-52.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000127091; ENSMUSP00000122856; ENSMUSG00000030849.
Organism-specific databases
MGI	MGI:95523. Fgfr2.
Phylogenomic databases
GeneTree	ENSGT00670000097694.
Family and domain databases
Gene3D	2.60.40.10. 1 hit.
InterPro	IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR013098. Ig_I-set. [Graphical view]
Pfam	PF07679. I-set. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	FGFR2. mouse.
NextBio	35559166.
SOURCE	Search...

Entry information

Entry name

F7BDU9_MOUSE

Accession

Primary (citable) accession number: F7BDU9

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)