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F7B8E7

- F7B8E7_HORSE

UniProt

F7B8E7 - F7B8E7_HORSE

Protein
Submitted name:

Uncharacterized protein

Gene

MME

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: UniProtKB
    2. peptide binding Source: UniProtKB
    3. zinc ion binding Source: UniProtKB

    GO - Biological processi

    1. beta-amyloid metabolic process Source: UniProtKB
    2. cellular response to cytokine stimulus Source: UniProtKB
    3. cellular response to UV-A Source: UniProtKB
    4. cellular response to UV-B Source: UniProtKB
    5. creatinine metabolic process Source: UniProtKB
    6. kidney development Source: UniProtKB
    7. peptide metabolic process Source: UniProtKB
    8. proteolysis Source: UniProtKB
    9. replicative senescence Source: UniProtKB
    10. sensory perception of pain Source: UniProtKB

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:MMEImported
    OrganismiEquus caballus (Horse)Imported
    Taxonomic identifieri9796 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
    ProteomesiUP000002281: Chromosome 16

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: UniProtKB
    2. brush border Source: UniProtKB
    3. cytoplasm Source: UniProtKB
    4. dendrite Source: UniProtKB
    5. neuron projection terminus Source: UniProtKB
    6. plasma membrane Source: UniProtKB
    7. synapse Source: UniProtKB
    8. synaptic vesicle Source: UniProtKB

    Structurei

    3D structure databases

    ProteinModelPortaliF7B8E7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00650000093248.
    KOiK01389.
    OMAiVWCGTYR.
    OrthoDBiEOG7PZRWQ.
    TreeFamiTF315192.

    Family and domain databases

    Gene3Di3.40.390.10. 2 hits.
    InterProiIPR024079. MetalloPept_cat_dom.
    IPR000718. Peptidase_M13.
    IPR018497. Peptidase_M13_C.
    IPR008753. Peptidase_M13_N.
    [Graphical view]
    PANTHERiPTHR11733. PTHR11733. 1 hit.
    PfamiPF01431. Peptidase_M13. 1 hit.
    PF05649. Peptidase_M13_N. 1 hit.
    [Graphical view]
    PRINTSiPR00786. NEPRILYSIN.

    Sequencei

    Sequence statusi: Complete.

    F7B8E7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRSESQMDI TDINTPKPKK QQRWTPLEVS LSVLVVLLTV IAVTTIALYA    50
    TYDDGICKSS DCIKSAARLI QNMDATAEPC ANFFKYACGG WLKRNIIPET 100
    SSRYGNFDIL RDELEVVLKD VLQETKTEDI AAVQKAKTLY RSCVNESVID 150
    SRGGEPLLRL LPDIYDWPVA TENWEQVYGT SWTAEKSIAQ LNSKYGKKVI 200
    INFFVGTDDK NSMNHIIHID QPRLGLPSRD YYECTGIYKE ACTAYVDFMI 250
    SVAKLIRQEK GLPIDENQLS SEMNKVMELE KEIANATAKP EDRNDPILLY 300
    NKMTLAQIQS NFSLEINGKP FSWANFTNEI MSTVNINIPN EEDVVVYAPE 350
    YLTKLKLILT KYSARDLQNL MSWRFIMDLV SSLSRTYKES RNAFRKALYG 400
    TTSETATWRR CANYVNGNME NAVGRLYVEA AFAGESKHVV ENLIAQIREV 450
    FIQTLDDLTW MDAETKKKAE EKALAIKERI GYPDEIISND SKLDNEYLEL 500
    NYKEDEYFEN IIQNLKFSQN KQLKKLREKV DKDEWISGAA VVNAFYSSGR 550
    NQIVFPAGIL QPPFFSAQQS NSLNYGGIGM VIGHEITHGF DDNGRNFNKD 600
    GDLVDWWTQQ SANNFKEQSQ CMVYQYGNFS WDLAGGQHLN GINTLGENIA 650
    DNGGIGQAYR AYQNYVKKNG EEKLLPGIDL NHKQLFFLNF AQVWCGTYRP 700
    EYAINSIKTD VHSPGSFRII GTLQNSPEFS EAFHCPKNSY MNPEKKCRVW 750
    Length:750
    Mass (Da):85,407
    Last modified:July 27, 2011 - v1
    Checksum:iE03A3D0F9D600D2D
    GO

    Sequence databases

    RefSeqiXP_001488195.1. XM_001488145.3.
    XP_005601072.1. XM_005601015.1.
    XP_005601073.1. XM_005601016.1.
    XP_005601074.1. XM_005601017.1.

    Genome annotation databases

    EnsembliENSECAT00000010316; ENSECAP00000007949; ENSECAG00000009138.
    GeneIDi100053541.
    KEGGiecb:100053541.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_001488195.1. XM_001488145.3.
    XP_005601072.1. XM_005601015.1.
    XP_005601073.1. XM_005601016.1.
    XP_005601074.1. XM_005601017.1.

    3D structure databases

    ProteinModelPortali F7B8E7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSECAT00000010316 ; ENSECAP00000007949 ; ENSECAG00000009138 .
    GeneIDi 100053541.
    KEGGi ecb:100053541.

    Organism-specific databases

    CTDi 4311.

    Phylogenomic databases

    GeneTreei ENSGT00650000093248.
    KOi K01389.
    OMAi VWCGTYR.
    OrthoDBi EOG7PZRWQ.
    TreeFami TF315192.

    Family and domain databases

    Gene3Di 3.40.390.10. 2 hits.
    InterProi IPR024079. MetalloPept_cat_dom.
    IPR000718. Peptidase_M13.
    IPR018497. Peptidase_M13_C.
    IPR008753. Peptidase_M13_N.
    [Graphical view ]
    PANTHERi PTHR11733. PTHR11733. 1 hit.
    Pfami PF01431. Peptidase_M13. 1 hit.
    PF05649. Peptidase_M13_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00786. NEPRILYSIN.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
      Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
      Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
      , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
      Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThoroughbredImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: ThoroughbredImported.

    Entry informationi

    Entry nameiF7B8E7_HORSE
    AccessioniPrimary (citable) accession number: F7B8E7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3