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F7B8E7

- F7B8E7_HORSE

UniProt

F7B8E7 - F7B8E7_HORSE

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Protein
Submitted name: Uncharacterized protein
Gene
MME
Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. metalloendopeptidase activity Source: UniProtKB
  2. peptide binding Source: UniProtKB
  3. zinc ion binding Source: UniProtKB
Complete GO annotation...

GO - Biological processi

  1. beta-amyloid metabolic process Source: UniProtKB
  2. cellular response to UV-A Source: UniProtKB
  3. cellular response to UV-B Source: UniProtKB
  4. cellular response to cytokine stimulus Source: UniProtKB
  5. creatinine metabolic process Source: UniProtKB
  6. kidney development Source: UniProtKB
  7. peptide metabolic process Source: UniProtKB
  8. proteolysis Source: UniProtKB
  9. replicative senescence Source: UniProtKB
  10. sensory perception of pain Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:MMEImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281: Chromosome 16

Subcellular locationi

GO - Cellular componenti

  1. axon Source: UniProtKB
  2. brush border Source: UniProtKB
  3. cytoplasm Source: UniProtKB
  4. dendrite Source: UniProtKB
  5. neuron projection terminus Source: UniProtKB
  6. plasma membrane Source: UniProtKB
  7. synapse Source: UniProtKB
  8. synaptic vesicle Source: UniProtKB
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliF7B8E7.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00650000093248.
KOiK01389.
OMAiVWCGTYR.
OrthoDBiEOG7PZRWQ.
TreeFamiTF315192.

Family and domain databases

Gene3Di3.40.390.10. 2 hits.
InterProiIPR024079. MetalloPept_cat_dom.
IPR000718. Peptidase_M13.
IPR018497. Peptidase_M13_C.
IPR008753. Peptidase_M13_N.
[Graphical view]
PANTHERiPTHR11733. PTHR11733. 1 hit.
PfamiPF01431. Peptidase_M13. 1 hit.
PF05649. Peptidase_M13_N. 1 hit.
[Graphical view]
PRINTSiPR00786. NEPRILYSIN.

Sequencei

Sequence statusi: Complete.

F7B8E7-1 [UniParc]FASTAAdd to Basket

« Hide

MGRSESQMDI TDINTPKPKK QQRWTPLEVS LSVLVVLLTV IAVTTIALYA    50
TYDDGICKSS DCIKSAARLI QNMDATAEPC ANFFKYACGG WLKRNIIPET 100
SSRYGNFDIL RDELEVVLKD VLQETKTEDI AAVQKAKTLY RSCVNESVID 150
SRGGEPLLRL LPDIYDWPVA TENWEQVYGT SWTAEKSIAQ LNSKYGKKVI 200
INFFVGTDDK NSMNHIIHID QPRLGLPSRD YYECTGIYKE ACTAYVDFMI 250
SVAKLIRQEK GLPIDENQLS SEMNKVMELE KEIANATAKP EDRNDPILLY 300
NKMTLAQIQS NFSLEINGKP FSWANFTNEI MSTVNINIPN EEDVVVYAPE 350
YLTKLKLILT KYSARDLQNL MSWRFIMDLV SSLSRTYKES RNAFRKALYG 400
TTSETATWRR CANYVNGNME NAVGRLYVEA AFAGESKHVV ENLIAQIREV 450
FIQTLDDLTW MDAETKKKAE EKALAIKERI GYPDEIISND SKLDNEYLEL 500
NYKEDEYFEN IIQNLKFSQN KQLKKLREKV DKDEWISGAA VVNAFYSSGR 550
NQIVFPAGIL QPPFFSAQQS NSLNYGGIGM VIGHEITHGF DDNGRNFNKD 600
GDLVDWWTQQ SANNFKEQSQ CMVYQYGNFS WDLAGGQHLN GINTLGENIA 650
DNGGIGQAYR AYQNYVKKNG EEKLLPGIDL NHKQLFFLNF AQVWCGTYRP 700
EYAINSIKTD VHSPGSFRII GTLQNSPEFS EAFHCPKNSY MNPEKKCRVW 750
Length:750
Mass (Da):85,407
Last modified:July 27, 2011 - v1
Checksum:iE03A3D0F9D600D2D
GO

Sequence databases

RefSeqiXP_001488195.1. XM_001488145.3.
XP_005601072.1. XM_005601015.1.
XP_005601073.1. XM_005601016.1.
XP_005601074.1. XM_005601017.1.

Genome annotation databases

EnsembliENSECAT00000010316; ENSECAP00000007949; ENSECAG00000009138.
GeneIDi100053541.
KEGGiecb:100053541.

Cross-referencesi

Sequence databases

RefSeqi XP_001488195.1. XM_001488145.3.
XP_005601072.1. XM_005601015.1.
XP_005601073.1. XM_005601016.1.
XP_005601074.1. XM_005601017.1.

3D structure databases

ProteinModelPortali F7B8E7.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSECAT00000010316 ; ENSECAP00000007949 ; ENSECAG00000009138 .
GeneIDi 100053541.
KEGGi ecb:100053541.

Organism-specific databases

CTDi 4311.

Phylogenomic databases

GeneTreei ENSGT00650000093248.
KOi K01389.
OMAi VWCGTYR.
OrthoDBi EOG7PZRWQ.
TreeFami TF315192.

Family and domain databases

Gene3Di 3.40.390.10. 2 hits.
InterProi IPR024079. MetalloPept_cat_dom.
IPR000718. Peptidase_M13.
IPR018497. Peptidase_M13_C.
IPR008753. Peptidase_M13_N.
[Graphical view ]
PANTHERi PTHR11733. PTHR11733. 1 hit.
Pfami PF01431. Peptidase_M13. 1 hit.
PF05649. Peptidase_M13_N. 1 hit.
[Graphical view ]
PRINTSi PR00786. NEPRILYSIN.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF7B8E7_HORSE
AccessioniPrimary (citable) accession number: F7B8E7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 16, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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