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Protein

Palmitoyltransferase

Gene

ZDHHC24

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:ZDHHC24Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 12

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 40HelicalUniRule annotationAdd BLAST21
Transmembranei52 – 73HelicalUniRule annotationAdd BLAST22
Transmembranei142 – 165HelicalUniRule annotationAdd BLAST24
Transmembranei204 – 222HelicalUniRule annotationAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF6ZZE9.
PRIDEiF6ZZE9.

Expressioni

Gene expression databases

BgeeiENSECAG00000013900.

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000011604.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 232DHHCInterPro annotationAdd BLAST139

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
InParanoidiF6ZZE9.
KOiK18932.
OMAiRCVGFRN.
OrthoDBiEOG091G0RWR.
TreeFamiTF319523.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

F6ZZE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQPWAAGSA EWAPARLPLV LTALWAAAVG LELAYVLVLG PGPPPLGPLA
60 70 80 90 100
RTLQLALAAF QLLNLLGNVG LFLRSDPSIR GVMLAGRGLG QGWAYCYQCQ
110 120 130 140 150
SQVPPRSGHC SACRVCILRR DHHCRLLGRC VGFRNYRPFL CLLLHAAGVL
160 170 180 190 200
LHVSVLLGPA LSALLRAHAP LHTAALLLLP WLMLLTGRVS LAQFALAFVT
210 220 230 240 250
DTCVAGALLC GAGLLFHGML LLRGQTTWEW ARGQHSYDLG PYHNLQAALG
260 270 280
PRWVLVWLWP FLASPLPGDG ITFQTTADVG LMAS
Length:284
Mass (Da):30,480
Last modified:July 27, 2011 - v1
Checksum:i61A22A7E29B515CA
GO

Sequence databases

RefSeqiXP_001491512.2. XM_001491462.5.

Genome annotation databases

EnsembliENSECAT00000014510; ENSECAP00000011604; ENSECAG00000013900.
GeneIDi100058529.
KEGGiecb:100058529.

Similar proteinsi

Entry informationi

Entry nameiF6ZZE9_HORSE
AccessioniPrimary (citable) accession number: F6ZZE9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: August 30, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported