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F6ZXQ6

- F6ZXQ6_MACMU

UniProt

F6ZXQ6 - F6ZXQ6_MACMU

Protein

Vasopressin V1a receptor

Gene

AVPR1A

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.UniRule annotation

    GO - Molecular functioni

    1. vasopressin receptor activity Source: InterPro

    GO - Biological processi

    1. regulation of systemic arterial blood pressure by vasopressin Source: Ensembl

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Vasopressin V1a receptorUniRule annotation
    Gene namesi
    Name:AVPR1AImported
    OrganismiMacaca mulatta (Rhesus macaque)Imported
    Taxonomic identifieri9544 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
    ProteomesiUP000006718: Chromosome 11

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Keywords - PTMi

    GlycoproteinUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF6ZXQ6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00660000095384.
    KOiK04226.
    OMAiTITIVAC.
    OrthoDBiEOG7Z69CP.
    TreeFamiTF106499.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR015076. DUF1856.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR001817. Vasoprsn_rcpt.
    IPR001224. Vprs_V1A_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    PF08983. DUF1856. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00896. VASOPRESSINR.
    PR00752. VASOPRSNV1AR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6ZXQ6-1 [UniParc]FASTAAdd to Basket

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    MDSMRFSAGP DAGPSGNSSL WWPLATSAGN TSREAEALGE DNGPPRDVRN    50
    EELAKLEIAV LAVTFTVAVL GNSSVLLALH RTPRKTSRMH LFIRHLSLAD 100
    LAVAFFQVLP QMCWDITYRF RGPDWLCRVV KHLQVFGMFA SAYMLVVMTA 150
    DRYIAVCHPL KTLQQPARRS RLMIAAAWVL SFVLSTPQYF VFSMIEVNNV 200
    TKARDCWATF IQPWGSRAYV TWMTGGIFVA PVVILGTCYG FICYNIWRNV 250
    RGKTASRQSK GAAQAGAAFQ KGFLLAPCVS SVKSISRAKI RTVKMTFVIV 300
    TAYIVCWAPF FIIQMWSVWD PKSVWTESEN PTITITALLG SLNSCCNPWI 350
    YMFFSGHLLQ DCVQSFPCCQ NIKEKFNKED TDSMSRRQTF YSNNRSPTNS 400
    TGMWKDSPKS SKSIKFLPIS T 421
    Length:421
    Mass (Da):47,261
    Last modified:July 27, 2011 - v1
    Checksum:i66869C0B281BAB47
    GO

    Sequence databases

    RefSeqiXP_001116798.2. XM_001116798.2.

    Genome annotation databases

    EnsembliENSMMUT00000000798; ENSMMUP00000000738; ENSMMUG00000000549.
    GeneIDi717041.
    KEGGimcc:717041.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_001116798.2. XM_001116798.2.

    3D structure databases

    ProteinModelPortali F6ZXQ6.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMMUT00000000798 ; ENSMMUP00000000738 ; ENSMMUG00000000549 .
    GeneIDi 717041.
    KEGGi mcc:717041.

    Organism-specific databases

    CTDi 552.

    Phylogenomic databases

    GeneTreei ENSGT00660000095384.
    KOi K04226.
    OMAi TITIVAC.
    OrthoDBi EOG7Z69CP.
    TreeFami TF106499.

    Miscellaneous databases

    NextBioi 19960304.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR015076. DUF1856.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR001817. Vasoprsn_rcpt.
    IPR001224. Vprs_V1A_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    PF08983. DUF1856. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00896. VASOPRESSINR.
    PR00752. VASOPRSNV1AR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolutionary and biomedical insights from the rhesus macaque genome."
      Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
      , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
      Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 17573Imported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: 17573Imported.

    Entry informationi

    Entry nameiF6ZXQ6_MACMU
    AccessioniPrimary (citable) accession number: F6ZXQ6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3