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Protein
Submitted name:

Glutamate receptor 1

Gene

Gria1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate receptor 1Imported
Gene namesi
Name:Gria1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:95808. Gria1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei466 – 48823HelicalSequence analysisAdd
BLAST
Transmembranei549 – 57123HelicalSequence analysisAdd
BLAST
Transmembranei739 – 76123HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Proteomic databases

PaxDbiF6YNQ1.

Expressioni

Gene expression databases

BgeeiF6YNQ1.
ExpressionAtlasiF6YNQ1. baseline and differential.
GenevisibleiF6YNQ1. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044494.

Chemistry

BindingDBiF6YNQ1.

Structurei

3D structure databases

ProteinModelPortaliF6YNQ1.
SMRiF6YNQ1. Positions 1-762.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini339 – 714376PBPeInterPro annotationAdd
BLAST
Domaini349 – 41466Lig_chan-Glu_bdInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1054. Eukaryota.
ENOG410XPSH. LUCA.
GeneTreeiENSGT00760000118920.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
PF00060. Lig_chan. 1 hit.
PF10613. Lig_chan-Glu_bd. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

F6YNQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYRFCSQFS KGVYAIFGFY ERRTVNMLTS FCGALHVCFI TPSFPVDTSN
60 70 80 90 100
QFVLQLRPEL QEALISIIDH YKWQTFVYIY DADRGLSVLQ RVLDTAAEKN
110 120 130 140 150
WQVTAVNILT TTEEGYRMLF QDLEKKKERL VVVDCESERL NAILGQIVKL
160 170 180 190 200
EKNGIGYHYI LANLGFMDID LNKFKESGAN VTGFQLVNYT DTIPARIMQQ
210 220 230 240 250
WRTSDARDHT RVDWKRPKYT SALTYDGVKV MAEAFQSLRR QRIDISRRGN
260 270 280 290 300
AGDCLANPAV PWGQGIDIQR ALQQVRFEGL TGNVQFNEKG RRTNYTLHVI
310 320 330 340 350
EMKHDGIRKI GYWNEDDKFV PAATDAQAGG DNSSVQNRTY IVTTILEDPY
360 370 380 390 400
VMLKKNANQF EGNDRYEGYC VELAAEIAKH VGYSYRLEIV SDGKYGARDP
410 420 430 440 450
DTKAWNGMVG ELVYGRADVA VAPLTITLVR EEVIDFSKPF MSLGISIMIK
460 470 480 490 500
KPQKSKPGVF SFLDPLAYEI WMCIVFAYIG VSVVLFLVSR FSPYEWHSEE
510 520 530 540 550
FEEGRDQTTS DQSNEFGIFN SLWFSLGAFM QQGCDISPRS LSGRIVGGVW
560 570 580 590 600
WFFTLIIISS YTANLAAFLT VERMVSPIES AEDLAKQTEI AYGTLEAGST
610 620 630 640 650
KEFFRRSKIA VFEKMWTYMK SAEPSVFVRT TEEGMIRVRK SKGKYAYLLE
660 670 680 690 700
STMNEYIEQR KPCDTMKVGG NLDSKGYGIA TPKGSALRGP VNLAVLKLSE
710 720 730 740 750
QGVLDKLKSK WWYDKGECGS KDSGSKDKTS ALSLSNVAGV FYILIGGLGL
760 770 780 790 800
AMLVALIEFC YKSRSESKRM KGFCLIPQQS INEAIRTSTL PRNSGAGASG
810 820 830
GSGSGENGRV VSQDFPKSMQ SIPCMSHSSG MPLGATGL
Length:838
Mass (Da):93,968
Last modified:November 16, 2011 - v1
Checksum:iDF63B4852EA6879A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663055 Genomic DNA. No translation available.
AL672177 Genomic DNA. No translation available.
AL954821 Genomic DNA. No translation available.
BX248119 Genomic DNA. No translation available.
RefSeqiNP_001239332.1. NM_001252403.1.
XP_006532297.1. XM_006532234.2.
UniGeneiMm.4920.

Genome annotation databases

EnsembliENSMUST00000151045; ENSMUSP00000117746; ENSMUSG00000020524.
GeneIDi14799.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663055 Genomic DNA. No translation available.
AL672177 Genomic DNA. No translation available.
AL954821 Genomic DNA. No translation available.
BX248119 Genomic DNA. No translation available.
RefSeqiNP_001239332.1. NM_001252403.1.
XP_006532297.1. XM_006532234.2.
UniGeneiMm.4920.

3D structure databases

ProteinModelPortaliF6YNQ1.
SMRiF6YNQ1. Positions 1-762.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044494.

Chemistry

BindingDBiF6YNQ1.

Proteomic databases

PaxDbiF6YNQ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000151045; ENSMUSP00000117746; ENSMUSG00000020524.
GeneIDi14799.

Organism-specific databases

CTDi2890.
MGIiMGI:95808. Gria1.

Phylogenomic databases

eggNOGiKOG1054. Eukaryota.
ENOG410XPSH. LUCA.
GeneTreeiENSGT00760000118920.

Miscellaneous databases

ChiTaRSiGria1. mouse.
NextBioi286953.
SOURCEiSearch...

Gene expression databases

BgeeiF6YNQ1.
ExpressionAtlasiF6YNQ1. baseline and differential.
GenevisibleiF6YNQ1. MM.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
PF00060. Lig_chan. 1 hit.
PF10613. Lig_chan-Glu_bd. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF6YNQ1_MOUSE
AccessioniPrimary (citable) accession number: F6YNQ1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 11, 2016
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.