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Protein
Submitted name:

Uncharacterized protein

Gene

AXIN1

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:AXIN1Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 13

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiF6YNJ2.
PRIDEiF6YNJ2.

Expressioni

Gene expression databases

ExpressionAtlasiF6YNJ2. baseline.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000021225.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini88 – 211124RGSInterPro annotationAdd
BLAST
Domaini785 – 86783DIXInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili389 – 41931Sequence analysisAdd
BLAST
Coiled coili709 – 73224Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 RGS domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3589. Eukaryota.
ENOG410YMJD. LUCA.
GeneTreeiENSGT00390000010011.
InParanoidiF6YNJ2.
KOiK02157.
OMAiWHHFPPR.
OrthoDBiEOG79PJQ0.
TreeFamiTF315454.

Family and domain databases

Gene3Di1.10.196.10. 2 hits.
InterProiIPR029797. AXIN1.
IPR014936. Axin_b-cat-bd.
IPR032101. Axin_TNKS_BD.
IPR001158. DIX.
IPR016137. RGS.
IPR024066. RGS_subdom1.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10845:SF11. PTHR10845:SF11. 1 hit.
PfamiPF16646. AXIN1_TNKS_BD. 1 hit.
PF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6YNJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDPRPV SHSFCSGKGP
60 70 80 90 100
GIKGETSTAT PRRSDLDLGY EPEGSASPTP PYLKWAESLH SLLDDQDGIN
110 120 130 140 150
LFRTFLKQED CADLLDFWFA CSGFRKLEPC DSNEEKRLKL AKAIYRKYIL
160 170 180 190 200
DNNGIVSRQT KPATKSFIKD CIMKQLIDPA MFDQAQTEIQ STMEENTYPS
210 220 230 240 250
FLKSDIYLEY TRTGSESPKL CSDQSSGSGT GKGIPGYLPT LNEDEEWKCD
260 270 280 290 300
QDVDEDDGRD PGPPGRLTQK LLLETAAPRA SASRRYSEGR EFRYGSWREP
310 320 330 340 350
VNPYYVNSGY ALAPATSAND SEQQSLSSDA DSLSLTDSSV DGVPPYRIRK
360 370 380 390 400
QHRREMQESV QVNGRVPLPH IPRTYRMPKE IRVEPQKFAA ELIHRLEAIQ
410 420 430 440 450
RTREAEEKLE ERLKRVRMEE EGEDGDVSCG PPGASHKLPS APAWHHFPPR
460 470 480 490 500
YADMGCTGLR DAHEENPESI LDEHVQRVMR TPGCQSPGPG HRSPDSVHVP
510 520 530 540 550
KVPGVLGGIA PGHGKHALKS GAKLDAAGLH LHRHSHHHGH HGLARPKEQA
560 570 580 590 600
EAEAARRVQS SFSWALEQHG HTAKPRSHSE SVGAAHITSD GLTYSGKAGT
610 620 630 640 650
TCKRNTKKAE SGKSMGAEAP GPSEDAEKNQ KIMQWIIEGE KEISRHRKAG
660 670 680 690 700
HGSSGTKKQQ GHESSRPLSI ERPGAVHPWV SAQLRNSVQP SHLFIQDPTM
710 720 730 740 750
PPNPAPNPLT QLEEARRRLE EEEKRASKLP SKQRYVQEVI QRGRSCARPA
760 770 780 790 800
CTPVLSVVPA VSDLELSETE MKSQRKVGSS STQPCDSIVV AYYFCGEPIP
810 820 830 840 850
YRTLVRGRAV TLGQFKELLT KKGNYRYYFK KVSDEFDCGV VFEEVREDEA
860
VLPVFEEKII GKVEKVD
Length:867
Mass (Da):96,230
Last modified:July 27, 2011 - v1
Checksum:iAFAAAD3E4EAC49AC
GO

Sequence databases

RefSeqiXP_014585777.1. XM_014730291.1.

Genome annotation databases

EnsembliENSECAT00000025514; ENSECAP00000021225; ENSECAG00000023674.
GeneIDi100065116.
KEGGiecb:100065116.

Cross-referencesi

Sequence databases

RefSeqiXP_014585777.1. XM_014730291.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000021225.

Proteomic databases

PaxDbiF6YNJ2.
PRIDEiF6YNJ2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSECAT00000025514; ENSECAP00000021225; ENSECAG00000023674.
GeneIDi100065116.
KEGGiecb:100065116.

Organism-specific databases

CTDi8312.

Phylogenomic databases

eggNOGiKOG3589. Eukaryota.
ENOG410YMJD. LUCA.
GeneTreeiENSGT00390000010011.
InParanoidiF6YNJ2.
KOiK02157.
OMAiWHHFPPR.
OrthoDBiEOG79PJQ0.
TreeFamiTF315454.

Gene expression databases

ExpressionAtlasiF6YNJ2. baseline.

Family and domain databases

Gene3Di1.10.196.10. 2 hits.
InterProiIPR029797. AXIN1.
IPR014936. Axin_b-cat-bd.
IPR032101. Axin_TNKS_BD.
IPR001158. DIX.
IPR016137. RGS.
IPR024066. RGS_subdom1.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10845:SF11. PTHR10845:SF11. 1 hit.
PfamiPF16646. AXIN1_TNKS_BD. 1 hit.
PF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF6YNJ2_HORSE
AccessioniPrimary (citable) accession number: F6YNJ2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 8, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.