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F6YNJ2

- F6YNJ2_HORSE

UniProt

F6YNJ2 - F6YNJ2_HORSE

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Protein
Submitted name:

Uncharacterized protein

Gene

AXIN1

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. signal transducer activity Source: Ensembl

GO - Biological processi

  1. activation of protein kinase activity Source: Ensembl
  2. axial mesoderm formation Source: Ensembl
  3. canonical Wnt signaling pathway Source: Ensembl
  4. cellular protein complex assembly Source: Ensembl
  5. cytoplasmic microtubule organization Source: Ensembl
  6. dorsal/ventral axis specification Source: Ensembl
  7. genetic imprinting Source: Ensembl
  8. in utero embryonic development Source: Ensembl
  9. negative regulation of canonical Wnt signaling pathway Source: Ensembl
  10. negative regulation of fat cell differentiation Source: Ensembl
  11. negative regulation of protein metabolic process Source: Ensembl
  12. negative regulation of transcription elongation from RNA polymerase II promoter Source: Ensembl
  13. nucleocytoplasmic transport Source: Ensembl
  14. positive regulation of JNK cascade Source: Ensembl
  15. positive regulation of JUN kinase activity Source: Ensembl
  16. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  17. positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
  18. positive regulation of transcription, DNA-templated Source: Ensembl
  19. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  20. positive regulation of ubiquitin-protein transferase activity Source: Ensembl
  21. post-anal tail morphogenesis Source: Ensembl
  22. protein catabolic process Source: Ensembl
  23. protein homooligomerization Source: Ensembl
  24. protein polyubiquitination Source: Ensembl
  25. regulation of catenin import into nucleus Source: Ensembl
  26. sensory perception of sound Source: Ensembl
  27. termination of G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:AXIN1Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281: Chromosome 13

Subcellular locationi

GO - Cellular componenti

  1. beta-catenin destruction complex Source: Ensembl
  2. cell cortex Source: Ensembl
  3. cytoplasmic membrane-bounded vesicle Source: Ensembl
  4. cytoplasmic microtubule Source: Ensembl
  5. lateral plasma membrane Source: Ensembl
  6. nucleus Source: Ensembl
  7. perinuclear region of cytoplasm Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiF6YNJ2.

Family & Domainsi

Sequence similaritiesi

Contains 1 RGS domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000010011.
InParanoidiF6YNJ2.
OMAiIMQWIIE.
OrthoDBiEOG79PJQ0.
TreeFamiTF315454.

Family and domain databases

Gene3Di1.10.196.10. 2 hits.
InterProiIPR014936. Axin_b-cat-bd.
IPR001158. DIX.
IPR024066. Regulat_G_prot_signal_dom1.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6YNJ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDPRPV SHSFCSGKGP
60 70 80 90 100
GIKGETSTAT PRRSDLDLGY EPEGSASPTP PYLKWAESLH SLLDDQDGIN
110 120 130 140 150
LFRTFLKQED CADLLDFWFA CSGFRKLEPC DSNEEKRLKL AKAIYRKYIL
160 170 180 190 200
DNNGIVSRQT KPATKSFIKD CIMKQLIDPA MFDQAQTEIQ STMEENTYPS
210 220 230 240 250
FLKSDIYLEY TRTGSESPKL CSDQSSGSGT GKGIPGYLPT LNEDEEWKCD
260 270 280 290 300
QDVDEDDGRD PGPPGRLTQK LLLETAAPRA SASRRYSEGR EFRYGSWREP
310 320 330 340 350
VNPYYVNSGY ALAPATSAND SEQQSLSSDA DSLSLTDSSV DGVPPYRIRK
360 370 380 390 400
QHRREMQESV QVNGRVPLPH IPRTYRMPKE IRVEPQKFAA ELIHRLEAIQ
410 420 430 440 450
RTREAEEKLE ERLKRVRMEE EGEDGDVSCG PPGASHKLPS APAWHHFPPR
460 470 480 490 500
YADMGCTGLR DAHEENPESI LDEHVQRVMR TPGCQSPGPG HRSPDSVHVP
510 520 530 540 550
KVPGVLGGIA PGHGKHALKS GAKLDAAGLH LHRHSHHHGH HGLARPKEQA
560 570 580 590 600
EAEAARRVQS SFSWALEQHG HTAKPRSHSE SVGAAHITSD GLTYSGKAGT
610 620 630 640 650
TCKRNTKKAE SGKSMGAEAP GPSEDAEKNQ KIMQWIIEGE KEISRHRKAG
660 670 680 690 700
HGSSGTKKQQ GHESSRPLSI ERPGAVHPWV SAQLRNSVQP SHLFIQDPTM
710 720 730 740 750
PPNPAPNPLT QLEEARRRLE EEEKRASKLP SKQRYVQEVI QRGRSCARPA
760 770 780 790 800
CTPVLSVVPA VSDLELSETE MKSQRKVGSS STQPCDSIVV AYYFCGEPIP
810 820 830 840 850
YRTLVRGRAV TLGQFKELLT KKGNYRYYFK KVSDEFDCGV VFEEVREDEA
860
VLPVFEEKII GKVEKVD
Length:867
Mass (Da):96,230
Last modified:July 27, 2011 - v1
Checksum:iAFAAAD3E4EAC49AC
GO

Genome annotation databases

EnsembliENSECAT00000025514; ENSECAP00000021225; ENSECAG00000023674.

Cross-referencesi

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F6YNJ2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSECAT00000025514 ; ENSECAP00000021225 ; ENSECAG00000023674 .

Phylogenomic databases

GeneTreei ENSGT00390000010011.
InParanoidi F6YNJ2.
OMAi IMQWIIE.
OrthoDBi EOG79PJQ0.
TreeFami TF315454.

Family and domain databases

Gene3Di 1.10.196.10. 2 hits.
InterProi IPR014936. Axin_b-cat-bd.
IPR001158. DIX.
IPR024066. Regulat_G_prot_signal_dom1.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view ]
PRINTSi PR01301. RGSPROTEIN.
SMARTi SM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view ]
SUPFAMi SSF48097. SSF48097. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF6YNJ2_HORSE
AccessioniPrimary (citable) accession number: F6YNJ2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3