F6YNJ2 (F6YNJ2_HORSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSECAP00000021225

Gene names

Name:

AXIN1 Ensembl ENSECAP00000021225

Organism

Equus caballus (Horse) [Reference proteome] Ensembl ENSECAP00000021225

Taxonomic identifier

9796 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › Equus

Protein attributes

Sequence length	867 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 RGS domain. RuleBase RU003298
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSECAP00000021225

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	activation of protein kinase activity Inferred from electronic annotation. Source: Compara axial mesoderm formation Inferred from electronic annotation. Source: Compara canonical Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara cellular protein complex assembly Inferred from electronic annotation. Source: Compara cytoplasmic microtubule organization Inferred from electronic annotation. Source: Compara dorsal/ventral axis specification Inferred from electronic annotation. Source: Compara genetic imprinting Inferred from electronic annotation. Source: Compara in utero embryonic development Inferred from electronic annotation. Source: Compara negative regulation of canonical Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of fat cell differentiation Inferred from electronic annotation. Source: Compara negative regulation of protein metabolic process Inferred from electronic annotation. Source: Compara negative regulation of transcription elongation from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara nucleocytoplasmic transport Inferred from electronic annotation. Source: Compara positive regulation of JNK cascade Inferred from electronic annotation. Source: Compara positive regulation of JUN kinase activity Inferred from electronic annotation. Source: Compara positive regulation of peptidyl-serine phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of peptidyl-threonine phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of proteasomal ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: Compara positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: Compara positive regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara positive regulation of transforming growth factor beta receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of ubiquitin-protein ligase activity Inferred from electronic annotation. Source: Compara post-anal tail morphogenesis Inferred from electronic annotation. Source: Compara protein catabolic process Inferred from electronic annotation. Source: Compara protein homooligomerization Inferred from electronic annotation. Source: Compara protein polyubiquitination Inferred from electronic annotation. Source: Compara regulation of catenin import into nucleus Inferred from electronic annotation. Source: Compara sensory perception of sound Inferred from electronic annotation. Source: Compara termination of G-protein coupled receptor signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular_component	beta-catenin destruction complex Inferred from electronic annotation. Source: Compara cell cortex Inferred from electronic annotation. Source: Compara cytoplasmic membrane-bounded vesicle Inferred from electronic annotation. Source: Compara cytoplasmic microtubule Inferred from electronic annotation. Source: Compara lateral plasma membrane Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara
Molecular_function	signal transducer activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F6YNJ2 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: AFAAAD3E4EAC49AC	FASTA	867	96,230
	10 20 30 40 50 60 MSVQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDPRPV SHSFCSGKGP GIKGETSTAT 70 80 90 100 110 120 PRRSDLDLGY EPEGSASPTP PYLKWAESLH SLLDDQDGIN LFRTFLKQED CADLLDFWFA 130 140 150 160 170 180 CSGFRKLEPC DSNEEKRLKL AKAIYRKYIL DNNGIVSRQT KPATKSFIKD CIMKQLIDPA 190 200 210 220 230 240 MFDQAQTEIQ STMEENTYPS FLKSDIYLEY TRTGSESPKL CSDQSSGSGT GKGIPGYLPT 250 260 270 280 290 300 LNEDEEWKCD QDVDEDDGRD PGPPGRLTQK LLLETAAPRA SASRRYSEGR EFRYGSWREP 310 320 330 340 350 360 VNPYYVNSGY ALAPATSAND SEQQSLSSDA DSLSLTDSSV DGVPPYRIRK QHRREMQESV 370 380 390 400 410 420 QVNGRVPLPH IPRTYRMPKE IRVEPQKFAA ELIHRLEAIQ RTREAEEKLE ERLKRVRMEE 430 440 450 460 470 480 EGEDGDVSCG PPGASHKLPS APAWHHFPPR YADMGCTGLR DAHEENPESI LDEHVQRVMR 490 500 510 520 530 540 TPGCQSPGPG HRSPDSVHVP KVPGVLGGIA PGHGKHALKS GAKLDAAGLH LHRHSHHHGH 550 560 570 580 590 600 HGLARPKEQA EAEAARRVQS SFSWALEQHG HTAKPRSHSE SVGAAHITSD GLTYSGKAGT 610 620 630 640 650 660 TCKRNTKKAE SGKSMGAEAP GPSEDAEKNQ KIMQWIIEGE KEISRHRKAG HGSSGTKKQQ 670 680 690 700 710 720 GHESSRPLSI ERPGAVHPWV SAQLRNSVQP SHLFIQDPTM PPNPAPNPLT QLEEARRRLE 730 740 750 760 770 780 EEEKRASKLP SKQRYVQEVI QRGRSCARPA CTPVLSVVPA VSDLELSETE MKSQRKVGSS 790 800 810 820 830 840 STQPCDSIVV AYYFCGEPIP YRTLVRGRAV TLGQFKELLT KKGNYRYYFK KVSDEFDCGV 850 860 VFEEVREDEA VLPVFEEKII GKVEKVD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence, comparative analysis, and population genetics of the domestic horse." Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T. , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K. Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Thoroughbred Ensembl ENSECAP00000021225.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Thoroughbred Ensembl ENSECAP00000021225.

Cross-references

Sequence databases
RefSeq	XP_001915952.1. XM_001915917.1.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	F6YNJ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSECAT00000025514; ENSECAP00000021225; ENSECAG00000023674.
GeneID	100065116.
KEGG	ecb:100065116.
Organism-specific databases
CTD	8312.
Phylogenomic databases
GeneTree	ENSGT00390000010011.
KO	K02157.
OMA	IMQWIIE.
Family and domain databases
Gene3D	1.10.196.10. 2 hits.
InterPro	IPR014936. Axin_b-cat-bd. IPR001158. DIX. IPR000342. Regulat_G_prot_signal. IPR024066. Regulat_G_prot_signal_dom1. IPR016137. Regulat_G_prot_signal_superfam. [Graphical view]
Pfam	PF08833. Axin_b-cat_bind. 1 hit. PF00778. DIX. 1 hit. PF00615. RGS. 1 hit. [Graphical view]
PRINTS	PR01301. RGSPROTEIN.
SMART	SM00021. DAX. 1 hit. SM00315. RGS. 1 hit. [Graphical view]
SUPFAM	SSF48097. Regulat_G_prot_signal_superfam. 1 hit.
PROSITE	PS50841. DIX. 1 hit. PS50132. RGS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6YNJ2_HORSE

Accession

Primary (citable) accession number: F6YNJ2

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)