Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Transglutaminase 3

Gene

TGM3

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei274UniRule annotation1
Active sitei332UniRule annotation1
Active sitei355UniRule annotation1
Metal bindingi395CalciumUniRule annotation1
Metal bindingi397CalciumUniRule annotation1
Metal bindingi445CalciumUniRule annotation1
Metal bindingi450CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transglutaminase 3Imported
Gene namesi
Name:TGM3Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 22

Organism-specific databases

VGNCiVGNC:24062 TGM3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF6YMM5
PRIDEiF6YMM5

Expressioni

Gene expression databases

BgeeiENSECAG00000023860

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000021268

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini266 – 358TGcInterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
InParanoidiF6YMM5
KOiK05620
OMAiKADNMIR
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

F6YMM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALEPQSIN WQMTSNRRAH NTHNFYDQEL ILRRGQAFNF LLSLNRNLSS
60 70 80 90 100
GERLGFIAST GPNASESAKT KAVFPLSNSG SGGGWSAQLV SSQDKVLTIS
110 120 130 140 150
ILTPANAPIG LYTLNLQIFS HGKEFTLKLG TFILLFNPWL QADSVFMSNR
160 170 180 190 200
AEREEYVQED AGIIYVGSAN RIGMMGWNFG QFEEGILNIS LAVLDHSLNF
210 220 230 240 250
RRDPATDVAR RSDPKYVGRV LSAMINGNDD NGVISGNWSG DYSGGRDPRN
260 270 280 290 300
WNGSVEILKA WKSSGFRPVR FGQCWVFAGT LNTVLRSLGI PARVITNFNS
310 320 330 340 350
AHDTDGNLSV DVYYDPMGNP LDKGRDSVWN FHVWNEAWFV RTDLGPSYNG
360 370 380 390 400
WQVLDATPQE RSQGVFQCGP ASVFGVREGD VDKDFDMPFV FAEVNADRIT
410 420 430 440 450
WIYDAYTGTQ KQSSSDSRSV GKYISTKAVG SSSRVDVTEK YKYPEGSSQE
460 470 480 490 500
RQVFGKALGK LKPRVSFGAT SAGSVESEEQ TPSISGTFKV AGILEVGREV
510 520 530 540 550
NLALLLKNLT DDVKTVSVNM TAWTIVYNGT LIHEVWKDSV TISLDPKEEK
560 570 580 590 600
RHPVKISYAQ YEKYLKADNM IRTTAVCQVT DEPEVVVERD VILDNPTLTL
610 620 630 640 650
EVLDEVRVQK PVHVQMLFSN PLDEPVKNCV LLVEGSGLLL GSLKIDVPAL
660 670 680 690
RPKERSRVRF EILPTRSGTK QLLADFSCDK FPAIKAMLSI DVAE
Length:694
Mass (Da):76,924
Last modified:July 27, 2011 - v1
Checksum:i1A0972F5211414B0
GO

Sequence databases

RefSeqiXP_001497639.1, XM_001497589.3

Genome annotation databases

EnsembliENSECAT00000025564; ENSECAP00000021268; ENSECAG00000023860
GeneIDi100053068
KEGGiecb:100053068

Similar proteinsi

Entry informationi

Entry nameiF6YMM5_HORSE
AccessioniPrimary (citable) accession number: F6YMM5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health