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F6YMM5

- F6YMM5_HORSE

UniProt

F6YMM5 - F6YMM5_HORSE

Protein
Submitted name:

Uncharacterized protein

Gene

TGM3

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei274 – 2741UniRule annotation
    Active sitei332 – 3321UniRule annotation
    Active sitei355 – 3551UniRule annotation
    Metal bindingi395 – 3951CalciumUniRule annotation
    Metal bindingi397 – 3971CalciumUniRule annotation
    Metal bindingi445 – 4451CalciumUniRule annotation
    Metal bindingi450 – 4501CalciumUniRule annotation

    GO - Molecular functioni

    1. calcium ion binding Source: Ensembl
    2. GDP binding Source: Ensembl
    3. GTPase activity Source: Ensembl
    4. GTP binding Source: Ensembl
    5. magnesium ion binding Source: Ensembl
    6. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. cell envelope organization Source: Ensembl
    2. keratinocyte differentiation Source: Ensembl
    3. peptide cross-linking Source: Ensembl
    4. protein tetramerization Source: Ensembl

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:TGM3Imported
    OrganismiEquus caballus (Horse)Imported
    Taxonomic identifieri9796 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
    ProteomesiUP000002281: Chromosome 22

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiF6YMM5.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115034.
    KOiK05620.
    OMAiEILPTRS.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6YMM5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSALEPQSIN WQMTSNRRAH NTHNFYDQEL ILRRGQAFNF LLSLNRNLSS    50
    GERLGFIAST GPNASESAKT KAVFPLSNSG SGGGWSAQLV SSQDKVLTIS 100
    ILTPANAPIG LYTLNLQIFS HGKEFTLKLG TFILLFNPWL QADSVFMSNR 150
    AEREEYVQED AGIIYVGSAN RIGMMGWNFG QFEEGILNIS LAVLDHSLNF 200
    RRDPATDVAR RSDPKYVGRV LSAMINGNDD NGVISGNWSG DYSGGRDPRN 250
    WNGSVEILKA WKSSGFRPVR FGQCWVFAGT LNTVLRSLGI PARVITNFNS 300
    AHDTDGNLSV DVYYDPMGNP LDKGRDSVWN FHVWNEAWFV RTDLGPSYNG 350
    WQVLDATPQE RSQGVFQCGP ASVFGVREGD VDKDFDMPFV FAEVNADRIT 400
    WIYDAYTGTQ KQSSSDSRSV GKYISTKAVG SSSRVDVTEK YKYPEGSSQE 450
    RQVFGKALGK LKPRVSFGAT SAGSVESEEQ TPSISGTFKV AGILEVGREV 500
    NLALLLKNLT DDVKTVSVNM TAWTIVYNGT LIHEVWKDSV TISLDPKEEK 550
    RHPVKISYAQ YEKYLKADNM IRTTAVCQVT DEPEVVVERD VILDNPTLTL 600
    EVLDEVRVQK PVHVQMLFSN PLDEPVKNCV LLVEGSGLLL GSLKIDVPAL 650
    RPKERSRVRF EILPTRSGTK QLLADFSCDK FPAIKAMLSI DVAE 694
    Length:694
    Mass (Da):76,924
    Last modified:July 27, 2011 - v1
    Checksum:i1A0972F5211414B0
    GO

    Sequence databases

    RefSeqiXP_001497639.1. XM_001497589.2.

    Genome annotation databases

    EnsembliENSECAT00000025564; ENSECAP00000021268; ENSECAG00000023860.
    GeneIDi100053068.
    KEGGiecb:100053068.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_001497639.1. XM_001497589.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F6YMM5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSECAT00000025564 ; ENSECAP00000021268 ; ENSECAG00000023860 .
    GeneIDi 100053068.
    KEGGi ecb:100053068.

    Organism-specific databases

    CTDi 7053.

    Phylogenomic databases

    GeneTreei ENSGT00740000115034.
    KOi K05620.
    OMAi EILPTRS.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
      Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
      Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
      , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
      Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThoroughbredImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: ThoroughbredImported.

    Entry informationi

    Entry nameiF6YMM5_HORSE
    AccessioniPrimary (citable) accession number: F6YMM5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3