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F6YMM5

- F6YMM5_HORSE

UniProt

F6YMM5 - F6YMM5_HORSE

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Protein
Submitted name:

Uncharacterized protein

Gene

TGM3

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei274 – 2741UniRule annotation
Active sitei332 – 3321UniRule annotation
Active sitei355 – 3551UniRule annotation
Metal bindingi395 – 3951CalciumUniRule annotation
Metal bindingi397 – 3971CalciumUniRule annotation
Metal bindingi445 – 4451CalciumUniRule annotation
Metal bindingi450 – 4501CalciumUniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: Ensembl
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. cell envelope organization Source: Ensembl
  2. keratinocyte differentiation Source: Ensembl
  3. peptide cross-linking Source: InterPro
  4. protein tetramerization Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM3Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281: Chromosome 22

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiF6YMM5.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiF6YMM5.
KOiK05620.
OMAiEILPTRS.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6YMM5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSALEPQSIN WQMTSNRRAH NTHNFYDQEL ILRRGQAFNF LLSLNRNLSS
60 70 80 90 100
GERLGFIAST GPNASESAKT KAVFPLSNSG SGGGWSAQLV SSQDKVLTIS
110 120 130 140 150
ILTPANAPIG LYTLNLQIFS HGKEFTLKLG TFILLFNPWL QADSVFMSNR
160 170 180 190 200
AEREEYVQED AGIIYVGSAN RIGMMGWNFG QFEEGILNIS LAVLDHSLNF
210 220 230 240 250
RRDPATDVAR RSDPKYVGRV LSAMINGNDD NGVISGNWSG DYSGGRDPRN
260 270 280 290 300
WNGSVEILKA WKSSGFRPVR FGQCWVFAGT LNTVLRSLGI PARVITNFNS
310 320 330 340 350
AHDTDGNLSV DVYYDPMGNP LDKGRDSVWN FHVWNEAWFV RTDLGPSYNG
360 370 380 390 400
WQVLDATPQE RSQGVFQCGP ASVFGVREGD VDKDFDMPFV FAEVNADRIT
410 420 430 440 450
WIYDAYTGTQ KQSSSDSRSV GKYISTKAVG SSSRVDVTEK YKYPEGSSQE
460 470 480 490 500
RQVFGKALGK LKPRVSFGAT SAGSVESEEQ TPSISGTFKV AGILEVGREV
510 520 530 540 550
NLALLLKNLT DDVKTVSVNM TAWTIVYNGT LIHEVWKDSV TISLDPKEEK
560 570 580 590 600
RHPVKISYAQ YEKYLKADNM IRTTAVCQVT DEPEVVVERD VILDNPTLTL
610 620 630 640 650
EVLDEVRVQK PVHVQMLFSN PLDEPVKNCV LLVEGSGLLL GSLKIDVPAL
660 670 680 690
RPKERSRVRF EILPTRSGTK QLLADFSCDK FPAIKAMLSI DVAE
Length:694
Mass (Da):76,924
Last modified:July 27, 2011 - v1
Checksum:i1A0972F5211414B0
GO

Sequence databases

RefSeqiXP_001497639.1. XM_001497589.2.

Genome annotation databases

EnsembliENSECAT00000025564; ENSECAP00000021268; ENSECAG00000023860.
GeneIDi100053068.
KEGGiecb:100053068.

Cross-referencesi

Sequence databases

RefSeqi XP_001497639.1. XM_001497589.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F6YMM5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSECAT00000025564 ; ENSECAP00000021268 ; ENSECAG00000023860 .
GeneIDi 100053068.
KEGGi ecb:100053068.

Organism-specific databases

CTDi 7053.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
InParanoidi F6YMM5.
KOi K05620.
OMAi EILPTRS.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF6YMM5_HORSE
AccessioniPrimary (citable) accession number: F6YMM5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 26, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3