F6YMM5 (F6YMM5_HORSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSECAP00000021268

Gene names

Name:

TGM3 Ensembl ENSECAP00000021268

Organism

Equus caballus (Horse) [Reference proteome] Ensembl ENSECAP00000021268

Taxonomic identifier

9796 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › Equus

Protein attributes

Sequence length	694 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSECAP00000021268

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell envelope organization Inferred from electronic annotation. Source: Compara keratinocyte differentiation Inferred from electronic annotation. Source: Compara peptide cross-linking Inferred from electronic annotation. Source: Compara protein tetramerization Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara extrinsic to internal side of plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	GDP binding Inferred from electronic annotation. Source: Compara GTP binding Inferred from electronic annotation. Source: Compara GTPase activity Inferred from electronic annotation. Source: Compara calcium ion binding Inferred from electronic annotation. Source: Compara magnesium ion binding Inferred from electronic annotation. Source: Compara protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	274	1	By similarity PIRSR PIRSR000459-1
	Active site	332	1	By similarity PIRSR PIRSR000459-1
	Active site	355	1	By similarity PIRSR PIRSR000459-1
	Metal binding	395	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	397	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	445	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	450	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	F6YMM5 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: 1A0972F5211414B0	FASTA	694	76,924
	10 20 30 40 50 60 MSALEPQSIN WQMTSNRRAH NTHNFYDQEL ILRRGQAFNF LLSLNRNLSS GERLGFIAST 70 80 90 100 110 120 GPNASESAKT KAVFPLSNSG SGGGWSAQLV SSQDKVLTIS ILTPANAPIG LYTLNLQIFS 130 140 150 160 170 180 HGKEFTLKLG TFILLFNPWL QADSVFMSNR AEREEYVQED AGIIYVGSAN RIGMMGWNFG 190 200 210 220 230 240 QFEEGILNIS LAVLDHSLNF RRDPATDVAR RSDPKYVGRV LSAMINGNDD NGVISGNWSG 250 260 270 280 290 300 DYSGGRDPRN WNGSVEILKA WKSSGFRPVR FGQCWVFAGT LNTVLRSLGI PARVITNFNS 310 320 330 340 350 360 AHDTDGNLSV DVYYDPMGNP LDKGRDSVWN FHVWNEAWFV RTDLGPSYNG WQVLDATPQE 370 380 390 400 410 420 RSQGVFQCGP ASVFGVREGD VDKDFDMPFV FAEVNADRIT WIYDAYTGTQ KQSSSDSRSV 430 440 450 460 470 480 GKYISTKAVG SSSRVDVTEK YKYPEGSSQE RQVFGKALGK LKPRVSFGAT SAGSVESEEQ 490 500 510 520 530 540 TPSISGTFKV AGILEVGREV NLALLLKNLT DDVKTVSVNM TAWTIVYNGT LIHEVWKDSV 550 560 570 580 590 600 TISLDPKEEK RHPVKISYAQ YEKYLKADNM IRTTAVCQVT DEPEVVVERD VILDNPTLTL 610 620 630 640 650 660 EVLDEVRVQK PVHVQMLFSN PLDEPVKNCV LLVEGSGLLL GSLKIDVPAL RPKERSRVRF 670 680 690 EILPTRSGTK QLLADFSCDK FPAIKAMLSI DVAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence, comparative analysis, and population genetics of the domestic horse." Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T. , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K. Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Thoroughbred Ensembl ENSECAP00000021268.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Thoroughbred Ensembl ENSECAP00000021268.

Cross-references

Sequence databases
RefSeq	XP_001497639.1. XM_001497589.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSECAT00000025564; ENSECAP00000021268; ENSECAG00000023860.
GeneID	100053068.
KEGG	ecb:100053068.
Organism-specific databases
CTD	7053.
Phylogenomic databases
GeneTree	ENSGT00690000101863.
KO	K05620.
OMA	LVHEVWK.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR013808. Transglutaminase_CS. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
PROSITE	PS00547. TRANSGLUTAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6YMM5_HORSE

Accession

Primary (citable) accession number: F6YMM5

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	March 6, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)