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F6YMM5

- F6YMM5_HORSE

UniProt

F6YMM5 - F6YMM5_HORSE

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Protein
Submitted name: Uncharacterized protein
Gene
TGM3
Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei274 – 2741 By similarityUniRule annotation
Active sitei332 – 3321 By similarityUniRule annotation
Active sitei355 – 3551 By similarityUniRule annotation
Metal bindingi395 – 3951Calcium By similarityUniRule annotation
Metal bindingi397 – 3971Calcium By similarityUniRule annotation
Metal bindingi445 – 4451Calcium By similarityUniRule annotation
Metal bindingi450 – 4501Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. GDP binding Source: Ensembl
  2. GTP binding Source: Ensembl
  3. GTPase activity Source: Ensembl
  4. calcium ion binding Source: Ensembl
  5. magnesium ion binding Source: Ensembl
  6. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. cell envelope organization Source: Ensembl
  2. keratinocyte differentiation Source: Ensembl
  3. peptide cross-linking Source: Ensembl
  4. protein tetramerization Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM3Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281: Chromosome 22

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiF6YMM5.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115034.
KOiK05620.
OMAiEILPTRS.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6YMM5-1 [UniParc]FASTAAdd to Basket

« Hide

MSALEPQSIN WQMTSNRRAH NTHNFYDQEL ILRRGQAFNF LLSLNRNLSS    50
GERLGFIAST GPNASESAKT KAVFPLSNSG SGGGWSAQLV SSQDKVLTIS 100
ILTPANAPIG LYTLNLQIFS HGKEFTLKLG TFILLFNPWL QADSVFMSNR 150
AEREEYVQED AGIIYVGSAN RIGMMGWNFG QFEEGILNIS LAVLDHSLNF 200
RRDPATDVAR RSDPKYVGRV LSAMINGNDD NGVISGNWSG DYSGGRDPRN 250
WNGSVEILKA WKSSGFRPVR FGQCWVFAGT LNTVLRSLGI PARVITNFNS 300
AHDTDGNLSV DVYYDPMGNP LDKGRDSVWN FHVWNEAWFV RTDLGPSYNG 350
WQVLDATPQE RSQGVFQCGP ASVFGVREGD VDKDFDMPFV FAEVNADRIT 400
WIYDAYTGTQ KQSSSDSRSV GKYISTKAVG SSSRVDVTEK YKYPEGSSQE 450
RQVFGKALGK LKPRVSFGAT SAGSVESEEQ TPSISGTFKV AGILEVGREV 500
NLALLLKNLT DDVKTVSVNM TAWTIVYNGT LIHEVWKDSV TISLDPKEEK 550
RHPVKISYAQ YEKYLKADNM IRTTAVCQVT DEPEVVVERD VILDNPTLTL 600
EVLDEVRVQK PVHVQMLFSN PLDEPVKNCV LLVEGSGLLL GSLKIDVPAL 650
RPKERSRVRF EILPTRSGTK QLLADFSCDK FPAIKAMLSI DVAE 694
Length:694
Mass (Da):76,924
Last modified:July 27, 2011 - v1
Checksum:i1A0972F5211414B0
GO

Sequence databases

RefSeqiXP_001497639.1. XM_001497589.2.

Genome annotation databases

EnsembliENSECAT00000025564; ENSECAP00000021268; ENSECAG00000023860.
GeneIDi100053068.
KEGGiecb:100053068.

Cross-referencesi

Sequence databases

RefSeqi XP_001497639.1. XM_001497589.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F6YMM5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSECAT00000025564 ; ENSECAP00000021268 ; ENSECAG00000023860 .
GeneIDi 100053068.
KEGGi ecb:100053068.

Organism-specific databases

CTDi 7053.

Phylogenomic databases

GeneTreei ENSGT00740000115034.
KOi K05620.
OMAi EILPTRS.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF6YMM5_HORSE
AccessioniPrimary (citable) accession number: F6YMM5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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