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F6Y855

- F6Y855_MACMU

UniProt

F6Y855 - F6Y855_MACMU

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Protein
Submitted name:

Uncharacterized protein

Gene

HK2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: Ensembl

GO - Biological processi

  1. apoptotic mitochondrial changes Source: Ensembl
  2. glucose metabolic process Source: Ensembl
  3. glycolytic process Source: UniProtKB-KW
  4. regulation of glucose import Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:HK2Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
ProteomesiUP000006718: Chromosome 13

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial outer membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiF6Y855. baseline.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6Y855-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLSDETLLE ISKRFRKEME KGLGATTHPT AAVKMLPTFV RSTPDGTEHG
60 70 80 90 100
EFLALDLGGT NFRVLWVKVT DNGLQKVEME NQIYAIPEDI MRGSGTQLFD
110 120 130 140 150
HIAECLANFM DKLQIKDKKL PLGFTFSFPC HQTKLDESFL VSWTKGFKSS
160 170 180 190 200
GVEGRDVVTL IRKAIQRRGD FDIDIVAVVN DTVGTMMTCG YDDHNCEIGL
210 220 230 240 250
IVGTGSNACY MEEMRHIDMV EGDEGRMCIN MEWGAFGDDG SLNDIRTEFD
260 270 280 290 300
QEIDMGSLNP GKQLFEKMIS GMYMGELVRL ILVKMAKEEL LFGGKLSPEL
310 320 330 340 350
LNTGRFETKD ISDIEGEKDG IRKAREVLMR LGLDPTQEDC VATHRICQIV
360 370 380 390 400
STRSASLCAA TLAAVLQRIK ENKGEERLRS TVGVDGSVYK KHPHFAKCLH
410 420 430 440 450
KTVRRLVPDC DVRFLRSEDG SGKGAAMVTA VAYRLADQHR ARQKTLEPLQ
460 470 480 490 500
LSHDQLLEVK RRMKVEMERG LSKETHAIAP VKMLPTYVCA TPDGTEKGDF
510 520 530 540 550
LALDLGGTNF RVLLVRVRNG KWGGVEMHNK IYAIPQEVMH GTGDELFDHI
560 570 580 590 600
VQCIADFLEY MGMKGVSLPL GFTFSFPCQQ NSLDESILLK WTKGFKASGC
610 620 630 640 650
EGEDVVTLLK EAIHRREEFD LDVVAVVNDT VGTMMTCGFE DPHCEVGLIV
660 670 680 690 700
GTGSNACYME EMRNVELVEG EEGRMCVNME WGAFGDNGCL DDFCTEFDVA
710 720 730 740 750
VDELSLNPGK QRFEKMISGM YLGEIVRNIL IDFTKRGLLF RGRISERLKT
760 770 780 790 800
RGIFETKFLS QIESDCLALL QVRAILQHLG LESTCDDSII VKEVCTVVAR
810 820 830 840 850
RAAQLCGAGM AAVVDKIREN RGLDALKVTV GVDGTLYKLH PHFAKVMHET
860 870 880
VKDLAPKCDV SFLQSEDGSG KGAALITAVA CRIREAGQR
Length:889
Mass (Da):98,899
Last modified:July 27, 2011 - v1
Checksum:iEF61A0AD35083F75
GO

Sequence databases

RefSeqiXP_001111663.1. XM_001111663.2.
UniGeneiMmu.13636.

Genome annotation databases

EnsembliENSMMUT00000043433; ENSMMUP00000036433; ENSMMUG00000011845.
GeneIDi710479.
KEGGimcc:710479.

Cross-referencesi

Sequence databases

RefSeqi XP_001111663.1. XM_001111663.2.
UniGenei Mmu.13636.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMMUT00000043433 ; ENSMMUP00000036433 ; ENSMMUG00000011845 .
GeneIDi 710479.
KEGGi mcc:710479.

Organism-specific databases

CTDi 3099.

Phylogenomic databases

GeneTreei ENSGT00390000017159.
KOi K00844.

Miscellaneous databases

NextBioi 19979479.

Gene expression databases

ExpressionAtlasi F6Y855. baseline.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary and biomedical insights from the rhesus macaque genome."
    Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
    , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
    Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 17573Imported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: 17573Imported.

Entry informationi

Entry nameiF6Y855_MACMU
AccessioniPrimary (citable) accession number: F6Y855
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 26, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3