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Protein
Submitted name:

CD4 molecule

Gene

CD4

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD4 moleculeImported
Gene namesi
Name:CD4Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei400 – 426HelicalSequence analysisAdd BLAST27

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500335118726 – 461Sequence analysisAdd BLAST436

Proteomic databases

PaxDbiF6Y6X8.

Expressioni

Gene expression databases

BgeeiENSECAG00000009049.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000007248.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 119Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST100

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.
GeneTreeiENSGT00390000001745.
InParanoidiF6Y6X8.
OMAiPEAGMWQ.
OrthoDBiEOG091G0AZL.
TreeFamiTF335974.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiView protein in InterPro
IPR000973. CD4.
IPR015274. CD4-extracel.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR013151. Immunoglobulin.
IPR021963. Tcell_CD4_Cterm.
PANTHERiPTHR11422:SF3. PTHR11422:SF3. 1 hit.
PfamiView protein in Pfam
PF05790. C2-set. 2 hits.
PF09191. CD4-extracel. 1 hit.
PF00047. ig. 1 hit.
PF12104. Tcell_CD4_C. 1 hit.
PRINTSiPR00692. CD4TCANTIGEN.
SMARTiView protein in SMART
SM00409. IG. 3 hits.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 4 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

F6Y6X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRGTSFGHL LLLLQLALLP AVTQGREVVL GKAGETVELP CQGSQKKNVF
60 70 80 90 100
FNWKYPSEVK ILGGQRTWWV KGNTKLKDRI ESKTTLWDQG SFPLIIKYLE
110 120 130 140 150
ITDSGTYICE VEDKKTEVEL LVFRLTANSH THSSIRLLLG QNLTLTLESP
160 170 180 190 200
SGSNPSVQWK GPRHQNTTQG SRFLLKLGLQ DSGTWTCTVS KDQKTLVFNI
210 220 230 240 250
NILVLAFQKV SRTVYAKEGT QAEFSFPLTF ADENLSGELQ WQAEGASSQQ
260 270 280 290 300
KWISFSSDNR KVSVTGVSSH LKLQVEEMLP LRFKLLQALP KHAGSGKLRL
310 320 330 340 350
FLAKGELQQE VNLVVMRLTR SQNDVTCQVL GPSSPKLMLS LKLENQTDQT
360 370 380 390 400
AKVSNSQKLV KVPDPETGTW QCLLSDNGKV LLESKIEVLA TSFPQASPKL
410 420 430 440 450
LAAVLGGVAG LLLFTGFFIF CCVKCWHRRR QAERMSQIKR LLSEKKTCQC
460
HHRFQKTVSP V
Length:461
Mass (Da):51,558
Last modified:July 27, 2011 - v1
Checksum:i73DFFD4D16CF47CB
GO

Genome annotation databases

EnsembliENSECAT00000009509; ENSECAP00000007248; ENSECAG00000009049.

Similar proteinsi

Entry informationi

Entry nameiF6Y6X8_HORSE
AccessioniPrimary (citable) accession number: F6Y6X8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: August 30, 2017
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported