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Protein
Submitted name:

Huntingtin

Gene

HTT

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
HuntingtinImported
Gene namesi
Name:HTTImported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati898 – 928HEATPROSITE-ProRule annotationAdd BLAST31

Phylogenomic databases

eggNOGiENOG410IDZV. Eukaryota.
ENOG410XSEC. LUCA.
GeneTreeiENSGT00390000015863.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR021133. HEAT_type_2.
IPR000091. Huntingtin.
IPR028426. Huntingtin_fam.
IPR024613. Huntingtin_middle-repeat.
PANTHERiPTHR10170. PTHR10170. 1 hit.
PfamiView protein in Pfam
PF12372. DUF3652. 1 hit.
PRINTSiPR00375. HUNTINGTIN.
SUPFAMiSSF48371. SSF48371. 6 hits.
PROSITEiView protein in PROSITE
PS50077. HEAT_REPEAT. 1 hit.

Sequencei

Sequence statusi: Complete.

F6XPL5-1 [UniParc]FASTAAdd to basket

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        10         20         30         40         50
MATLEKLMKA FESLKSFQQQ QQQQQQPPPP PPPPPPPPPQ LPQPPPQAQP
60 70 80 90 100
LLPQPQPPPP PPPPPPGPAA AEEPLHRPKK ELSATKKDRV NHCLTICENI
110 120 130 140 150
VAQSVRNSPE FQKLLGIAME LFLLCSDDAE SDVRMVADEC LNKVIKALMD
160 170 180 190 200
SNLPRLQLEL YKEIKKNGAP RSLRAALWRF AELAHLVRPQ KCRPYLVNLL
210 220 230 240 250
PCLTRTSKRP EESVQETLAA AVPKIMASFG NFANDNEIKV LLKAFIANLK
260 270 280 290 300
SSSPTIRRTA AGSAVSICQH SRRTHYFYSW LLNVLLGLLV PVEDEHSTLL
310 320 330 340 350
ILGVLLTLRY LVPLLQQQVK DTSLKGSFGV TRKEMEVSPS AEQLIQVYEL
360 370 380 390 400
TLHHTQHQDH NVVTGALELL QQLFRTPPPE LLQALTTVGG IRQLTEAKDE
410 420 430 440 450
SGGRSRSGSI VELIGNSGSS CSPVLSRKQK GKVLLGEEEA LEDDSESRSD
460 470 480 490 500
VSSSAFAASV KDEISGELTA SSGVSTPGSA GHDIITEQPR SQHTLQADSV
510 520 530 540 550
DLAGCDLTSS ATDGDEEDIL SHSSSQVSAV PSDPAMDLND GTQASSPISD
560 570 580 590 600
SSQTTTEGPD SAVTPSDSSE IVLDGADNQY LGPQIGQPQD EDEEATSVLP
610 620 630 640 650
DEASEAFRNS SMALQQAHLL KNMSHSRQPS DSSVDKFVSR DEATESGDQE
660 670 680 690 700
SKPCRIKGDI GQSTDDDSAP LVHCVRLLSA SFLLTGGKNV LVPDRDVRVS
710 720 730 740 750
VKALALSCVG AAVALHPESF FSKLYKVPLD TADYPEEQYV SDILNYIDHG
760 770 780 790 800
DPQVRGATAI LCGTLVCSIL SRSRFHVGEW MGTIRTLTGN TFSLADCVPL
810 820 830 840 850
LRKTLKDESS VTCKLACTAV RHCVMSLCSS SYSELGLQLL IDLLTLRNSS
860 870 880 890 900
YWLVRTELLE TLAEIDFRLV SFLEAKAENL HRGAHHYTGL LTLQERVLTS
910 920 930 940 950
VVIHLLGDED PRVRHVAAAS LIRLVPKLFY KCDQGQADPV VAVARDQSSV
960 970 980 990 1000
YLKLLMHETQ PPSHFSVSTI TRIYRGYNLL PSIIDVTMEN NLSRVIAAVS
1010 1020 1030 1040 1050
HELITSTTRA LTFGCCEALC LLSTAFPVCI WSLGWHCGVP PLSASDECRK
1060 1070 1080 1090 1100
SCTIGMATMI LTLLSSAWFP LDLSAHQDAL ILAGNLLAAS APKSLRSSWT
1110 1120 1130 1140 1150
SEEEANPAAT KQEEVWPALG DRALVPMVEQ LFSHLLKVIN ICAHVLDDVA
1160 1170 1180 1190 1200
PGPAIKAALP SLTNPPSLSP IRRKGKEKEP GEQASVPLSP KKGSEASAAS
1210 1220 1230 1240 1250
RQSDTSGPVT TSKSSSLGSF YHLPSYLKLH DVLKATHANY KVTLDLQNST
1260 1270 1280 1290 1300
EKFGGFLRSA LDVLSQILEL ATLQDIGKCV EEILGYLKSC FSREPMMATV
1310 1320 1330 1340 1350
CVQQLLKTLF GTNLASQFDG LSSNPSKSQG RVQRLGSSSV RPGLYHYCFM
1360 1370 1380 1390 1400
APYTHFTQAL ADASLRNMVQ AEQEHDTSGW FDVLQKVSTQ LKTNLTSVTK
1410 1420 1430 1440 1450
NRADKNAIHN HIRLFEPLVI KALKQYTTTT SVQLQKQVLD LLAQLVQLRV
1460 1470 1480 1490 1500
NYCLLDSDQV FIGFVLKQFE YIEVGQFRES EAIIPNIFFF LVLLSYERYH
1510 1520 1530 1540 1550
SKQIIGIPKI IQLCDGIMAS GRKAVTHAIP ALQPIVHDLF VLRGANKADA
1560 1570 1580 1590 1600
GKELETQKEV VVSMLLRLIQ YHQVLEMFIL VLQQCHKENE DKWKRLSRQI
1610 1620 1630 1640 1650
ADIILPMLAK QQMHIDSHEA LGVLNTLFEI LAPSSLRPVD MLLRSMFVTP
1660 1670 1680 1690 1700
NTMASVSTVQ LWISGILAIL RVLISQSTED IVLSRIQELT FSPYLISCPV
1710 1720 1730 1740 1750
ISRLRDGDSN SALEEHSEGK QIKTLPEETF SRFLLQLVGI LLEDIVTKQL
1760 1770 1780 1790 1800
KVEMSEQQHT FYCQELGTLL MCLIHIFKSG MFRRITAAAT RLFRSDGCGG
1810 1820 1830 1840 1850
SFYTLESLNL RARSMITTHP TLVLLWCQIL LLVNHTDYRW WAEVQQTPKR
1860 1870 1880 1890 1900
HSLSSTKLLS PQMSGEEEDS DLAAKLGMCN REIVRRGALI LFCDYVCQNL
1910 1920 1930 1940 1950
HDSEHLTWLI VNHIQDLISL SHEPPVQDFI SAVHRNSAAS GLFIQAIQSR
1960 1970 1980 1990 2000
CENLSTPTTL KKTLQCLEGI HLSQSGAVLT LYVDRLLCTP FRVLARMVDI
2010 2020 2030 2040 2050
LACRRVEMLL AANLQSSMAQ LPMEELNRIQ EYLQSSGLAQ RHQRLYSLLD
2060 2070 2080 2090 2100
RFRLSTLQDS LSPSPPVSSH PLDGDGHVSL ETVSPDKDWY IHLVKSQCWT
2110 2120 2130 2140 2150
RSDSALLEGA ELVNRIPAED MSAFMMNSEF NISLLAPCLS LGMSEISGGQ
2160 2170 2180 2190 2200
KSPLFEAARE VTLARVSGTV QRLPAVHHVF QPHLPAEPAA YWSSDDLFGL
2210 2220 2230 2240 2250
KLKQSLQAII VLCTSKYTVK AFHLICDWHS FPERRRTSGH SVTRFFPLAL
2260 2270 2280 2290 2300
SWHLIHEQIP LSLDLQAGLD CCCLALQLPG LWSVISSTEF VTHACSLIHC
2310 2320 2330 2340 2350
VHFILEAVAV QPGEQLLSPE RRRNTPKAIR EEEEVDANTQ NPKYITAACE
2360 2370 2380 2390 2400
MVAEMVESLQ SVLALGHKRN SSVPAFLTSV LRNIIVSLAR LPLVNSYTRV
2410 2420 2430 2440 2450
PPLVWKLGWS PKPGGEFGTA FPEIPVEFLQ EKEVCLTLSH VTFIFLGWTS
2460 2470 2480 2490 2500
RTQFEETWAT LLGVLVTQPL VMEQEESPPE EDTERTQINV LAVQAITSLV
2510 2520 2530 2540 2550
LSAMTVPVAG NPAVSCLEQQ PRNKPLKALD TRFGRKLSII RGIVEQEIQA
2560 2570 2580 2590 2600
MVSKRENIAT HHLYQAWDPV PSLSPATTGA LISHEKLLLQ TNPERELGSM
2610 2620 2630 2640 2650
SYKLGQVSIH SVWLGNNITP LREEEWGEEE EEEADTPAPS SPPTSPVNSR
2660 2670 2680 2690 2700
KHRAGVDIHS CSQFLLELYS RWILPSSSAR RTPAILISEV VRSLLVVSDL
2710 2720 2730 2740 2750
FTERSQFELM YVTLTELRRV HPSEDEILAQ YLVPTTCKAA AVLGMDKAVA
2760 2770 2780 2790 2800
EPVSRLLEST LRSSHLPSRV GALHGILYVL ECDLLDDTAK QLIPVISDYL
2810 2820 2830 2840 2850
LSSLKGLAHC VNTHSQQHVL VMCATAFYLI ENYPLDVGPE FSASIIQMCG
2860 2870 2880 2890 2900
VMLSGSEEST PSIIYHCALR GLERLLLSEQ LSRLDAESLV KLSVDRVNVH
2910 2920 2930 2940 2950
SPHRAMAALG LMLTCMYTGK EKISPGRTSD PNPAAPDSES VIVAMERVSV
2960 2970 2980 2990 3000
LFDRIRKGFP CEARVVARIL PQFLDDFFPP QDIMNKVIGE FLSNQQPYPQ
3010 3020 3030 3040 3050
FMATVVYKVF QTLHSTGQSS MVRDWVMLSL SNFTQRTPVA MAMWSLSCFF
3060 3070 3080 3090 3100
VSASTSPWVA AILPHVISRM GKLEQVDVNL FCLVATDFYR HQIEEELDRR
3110 3120 3130
AFQSVFEMVA APGSPYHRLL TCLRNVHKVS TC
Length:3,132
Mass (Da):346,651
Last modified:July 27, 2011 - v1
Checksum:i48292BD613D58602
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFV01137879 Genomic DNA. No translation available.
ACFV01137880 Genomic DNA. No translation available.
ACFV01137881 Genomic DNA. No translation available.
ACFV01137882 Genomic DNA. No translation available.
ACFV01137883 Genomic DNA. No translation available.
ACFV01137884 Genomic DNA. No translation available.
ACFV01137885 Genomic DNA. No translation available.
ACFV01137886 Genomic DNA. No translation available.
ACFV01137887 Genomic DNA. No translation available.
ACFV01137888 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCJAT00000027377; ENSCJAP00000025906; ENSCJAG00000014069.

Similar proteinsi

Entry informationi

Entry nameiF6XPL5_CALJA
AccessioniPrimary (citable) accession number: F6XPL5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: August 30, 2017
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported