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Protein
Submitted name:

Inhibitor of nuclear factor kappa-B kinase subunit beta

Gene

Ikbkb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-1169091 Activation of NF-kappaB in B cells
R-MMU-168638 NOD1/2 Signaling Pathway
R-MMU-1810476 RIP-mediated NFkB activation via ZBP1
R-MMU-202424 Downstream TCR signaling
R-MMU-209543 p75NTR recruits signalling complexes
R-MMU-209560 NF-kB is activated and signals survival
R-MMU-2871837 FCERI mediated NF-kB activation
R-MMU-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
R-MMU-5357905 Regulation of TNFR1 signaling
R-MMU-5357956 TNFR1-induced NFkappaB signaling pathway
R-MMU-5607764 CLEC7A (Dectin-1) signaling
R-MMU-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation
R-MMU-9020702 Interleukin-1 signaling
R-MMU-933542 TRAF6 mediated NF-kB activation
R-MMU-937039 IRAK1 recruits IKK complex
R-MMU-937041 IKK complex recruitment mediated by RIP1
R-MMU-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation

Names & Taxonomyi

Protein namesi
Submitted name:
Inhibitor of nuclear factor kappa-B kinase subunit betaImported
Gene namesi
Name:IkbkbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1338071 Ikbkb

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiF6XPL0
PeptideAtlasiF6XPL0

Expressioni

Gene expression databases

BgeeiENSMUSG00000031537
ExpressionAtlasiF6XPL0 baseline and differential

Structurei

3D structure databases

SMRiF6XPL0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 29IKKbetaNEMObindInterPro annotationAdd BLAST29

Phylogenomic databases

eggNOGiKOG4250 Eukaryota
ENOG410XRMU LUCA
GeneTreeiENSGT00910000144033

Family and domain databases

InterProiView protein in InterPro
IPR022007 IKKbetaNEMObind
PfamiView protein in Pfam
PF12179 IKKbetaNEMObind, 1 hit
SMARTiView protein in SMART
SM01239 IKKbetaNEMObind, 1 hit

Sequencei

Sequence statusi: Fragment.

F6XPL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
VAEAHALCSR LESALQDTVK EQDRSFTAQS SRNFS
Length:35
Mass (Da):3,883
Last modified:July 27, 2011 - v1
Checksum:i533D809C238A5C02
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121835 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000132279; ENSMUSP00000120049; ENSMUSG00000031537

Similar proteinsi

Entry informationi

Entry nameiF6XPL0_MOUSE
AccessioniPrimary (citable) accession number: F6XPL0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 25, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health