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Protein
Submitted name:

Probable global transcription activator SNF2L2

Gene

SMARCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Probable global transcription activator SNF2L2Imported
Gene namesi
Name:SMARCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000080503.20.
HGNCiHGNC:11098. SMARCA2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080503.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500672563925 – 228Sequence analysisAdd BLAST204

Proteomic databases

PeptideAtlasiF6XE55.
PRIDEiF6XE55.

Expressioni

Gene expression databases

BgeeiENSG00000080503.
ExpressionAtlasiF6XE55. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF6XE55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini105 – 175BromoInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili185 – 215Sequence analysisAdd BLAST31

Keywords - Domaini

BromodomainPROSITE-ProRule annotation, Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00550000074659.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiView protein in InterPro
IPR001487. Bromodomain.
IPR036427. Bromodomain-like_sf.
IPR018359. Bromodomain_CS.
IPR030088. SMARCA2.
PANTHERiPTHR10799:SF541. PTHR10799:SF541. 1 hit.
PfamiView protein in Pfam
PF00439. Bromodomain. 1 hit.
PRINTSiPR00503. BROMODOMAIN.
SMARTiView protein in SMART
SM00297. BROMO. 1 hit.
SUPFAMiSSF47370. SSF47370. 1 hit.
PROSITEiView protein in PROSITE
PS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

F6XE55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLAARCFA GLLILSPLTV ISDSRPADSG KAIEDGNLEE MEEEVRLKKR
60 70 80 90 100
KRRRNVDKDP AKEDVEKAKK RRGRPPAEKL SPNPPKLTKQ MNAIIDTVIN
110 120 130 140 150
YKDSSGRQLS EVFIQLPSRK ELPEYYELIR KPVDFKKIKE RIRNHKYRSL
160 170 180 190 200
GDLEKDVMLL CHNAQTFNLE GSQIYEDSIV LQSVFKSARQ KIAKEEESED
210 220
ESNEEEEEED EEESESEAKS VKVKIKLN
Length:228
Mass (Da):26,373
Last modified:February 17, 2016 - v2
Checksum:i2CA86AF78E97D758
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei228Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138755 Genomic DNA. No translation available.
AL359076 Genomic DNA. No translation available.
AL591644 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000423555; ENSP00000413057; ENSG00000080503.
UCSCiuc064rwh.1. human.

Similar proteinsi

Entry informationi

Entry nameiF6XE55_HUMAN
AccessioniPrimary (citable) accession number: F6XE55
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: February 17, 2016
Last modified: October 25, 2017
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported