F6WCX7 (F6WCX7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dual-specificity mitogen-activated protein kinase kinase 7 Ensembl ENSP00000443946

Gene names

Name:

MAP2K7 Ensembl ENSP00000443946

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000443946

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000443946

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F6WCX7 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: D53B8CF9CD6F8C0C	FASTA	461	51,810
	10 20 30 40 50 60 MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PTLQLPLAND GGSRSPSSES 70 80 90 100 110 120 SPQHPTPPAR PRHMLGLPST LFTPRSMESI EIDQKLQEIM KQTGYLTIGG QVPPSLWRGE 130 140 150 160 170 180 GGGPARLDPS WERQWGAGGG GRPGTLQPSL SSQRYQAEIN DLENLGEMGS GTCGQVWKMR 190 200 210 220 230 240 FRKTGHVIAV KQMRRSGNKE ENKRILMDLD VVLKSHDCPY IVQCFGTFIT NTDVFIAMEL 250 260 270 280 290 300 MGTCAEKLKK RMQGPIPERI LGKMTVAIVK ALYYLKEKHG VIHRDVKPSN ILLDERGQIK 310 320 330 340 350 360 LCDFGISGRL VDSKAKTRSA GCAAYMAPER IDPPDPTKPD YDIRADVWSL GISLVELATG 370 380 390 400 410 420 QFPYKNCKTD FEVLTKVLQE EPPLLPGHMG FSGDFQSFVK DCLTKDHRKR PKYNKLLEHS 430 440 450 460 FIKRYETLEV DVASWFKDVM AKTESPRTSG VLSQPHLPFF R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biology of human chromosome 19." Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M. Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC010336 Genomic DNA. No translation available.
IPI	IPI01022470.
3D structure databases
ProteinModelPortal	F6WCX7.
SMR	F6WCX7. Positions 123-444.
ModBase	Search...
Proteomic databases
PRIDE	F6WCX7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000545011; ENSP00000443946; ENSG00000076984.
Organism-specific databases
HGNC	HGNC:6847. MAP2K7.
GenAtlas	Search...
Phylogenomic databases
OMA	FKMSSLE.
PhylomeDB	F6WCX7.
Gene expression databases
ArrayExpress	F6WCX7.
Bgee	F6WCX7.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35510447.

Entry information

Entry name

F6WCX7_HUMAN

Accession

Primary (citable) accession number: F6WCX7

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.