F6WCA3 (F6WCA3_CIOIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Uncharacterized protein Ensembl ENSCINP00000017775
Organism	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) [Reference proteome] Ensembl ENSCINP00000017775
Taxonomic identifier	7719 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Tunicata › Ascidiacea › Enterogona › Phlebobranchia › Cionidae › Ciona

Protein attributes

Sequence length	855 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 DH (DBL-homology) domain. SAAS SAAS001331 Contains 1 PH domain. SAAS SAAS000219
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSCINP00000017775

Ontologies

Keywords
Domain	SH3 domain SAAS SAAS000980
Ligand	Metal-binding SAAS SAAS002219 Zinc SAAS SAAS002219
PTM	Phosphoprotein SAAS SAAS000980
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: InterPro regulation of Rho protein signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	Rho guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phospholipid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSCINP00000017775

Sequences

	Sequence		Length	Mass (Da)
	F6WCA3 [UniParc]. Last modified April 18, 2012. Version 2. Checksum: DDF463DB883EAAD5	FASTA	855	98,864
	10 20 30 40 50 60 KELWRQCVRW LTDTGVLPRD HKTCQPHAVV FDLAQTLRDG VILCNLLNVI QPGSVDFTQI 70 80 90 100 110 120 NLRPQMLQFS CLQNIRTTLH ALNNVFRLQE TFLPSDLYDM TNIPLVLQVL SLLSQTPASQ 130 140 150 160 170 180 YKFRPFPESH VGRKQMYNHE EEEDIYSNLA DMASQRDLAD EEENLYDSVP EDVDEGIYGS 190 200 210 220 230 240 LIAVKQATGT LKKDCYIQQD KRGYCITEII ETERNYVQHL TMMVGKFIEP FRQHQGIDEK 250 260 270 280 290 300 DIRAIFMNIE DLLPIHQDFL RELEKSSSES PSTLSRPFLK FKDRFLLYGL YCSKLIDAQD 310 320 330 340 350 360 HLEDVKKMNP RSGMFVEECE ARASPSKFKL RELLCVPMQR ILKYQLLVKE LNKHTIDKHP 370 380 390 400 410 420 DKGELAGALE SMQELSHYVN EVKRDSEMLI TINQVQSCLV EYSTQIPLNS YGRLQKDGEL 430 440 450 460 470 480 RIKSTMDKKA KSRNTFLFDQ ALFMTKEENG NYHLKDLLRL EEYKLEEIQQ SKGGKWTWNW 490 500 510 520 530 540 CLSATKNGCN SYMLYAKTAM DKTKWIEKLK DSFDNISPRE LKNKSHNFKM HSFSEPTYCN 550 560 570 580 590 600 NCNKLLLGTF YQGYWCQSTN AKCHKHCLGE ILKLSGSSGP EVPQRGKRTR PFDKFRFNKS 610 620 630 640 650 660 AAVPPPTMYR AHRDYNGNPR PPFPGVMTIS FSSHEYVMVD EEVNSDWWLG HTTTDLDRKG 670 680 690 700 710 720 YFPASFVSPV YHAKIRGSNT HFWNTRYAGT MDRGEAENLL HDKPSGTFLV RTRDGHLAIS 730 740 750 760 770 780 LIYSKEMKHI RINRSSEGLY FVAECKNFKS VQELIRYYRE NSMSSSFLGL ETSLQIPYRD 790 800 810 820 830 840 PNFFPVAANG TQYEVISRAV VLFNFSPRSP QELGLREGQP VNVISTAGDA HGWWKGESEG 850 QVGYFPATFV EEIRQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins." Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A., Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N., Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P., Martinez D. , Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S., Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K., Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P., Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S., Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G., Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A., Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M., Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D., Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F., Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N., Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M., Satoh N., Rokhsar D.S. Science 298:2157-2167(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EAAA01002834 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSCINT00000017775; ENSCINP00000017775; ENSCING00000008711.
Phylogenomic databases
GeneTree	ENSGT00700000104383.
Family and domain databases
Gene3D	1.10.418.10. 1 hit. 1.20.900.10. 1 hit. 2.30.29.30. 1 hit. 3.30.505.10. 1 hit.
InterPro	IPR001715. CH-domain. IPR000219. DH-domain. IPR001331. GDS_CDC24_CS. IPR011993. PH_like_dom. IPR001849. Pleckstrin_homology. IPR002219. Prot_Kinase_C-like_PE/DAG-bd. IPR000980. SH2. IPR011511. SH3_2. IPR001452. SH3_domain. [Graphical view]
Pfam	PF00130. C1_1. 1 hit. PF00307. CH. 1 hit. PF00621. RhoGEF. 1 hit. PF00017. SH2. 1 hit. PF07653. SH3_2. 2 hits. [Graphical view]
PRINTS	PR00401. SH2DOMAIN.
SMART	SM00109. C1. 1 hit. SM00033. CH. 1 hit. SM00233. PH. 1 hit. SM00325. RhoGEF. 1 hit. SM00252. SH2. 1 hit. SM00326. SH3. 2 hits. [Graphical view]
SUPFAM	SSF47576. Calponin-homology. 1 hit. SSF48065. DH-domain. 1 hit. SSF50044. SH3. 2 hits.
PROSITE	PS50021. CH. 1 hit. PS00741. DH_1. 1 hit. PS50010. DH_2. 1 hit. PS50003. PH_DOMAIN. 1 hit. PS50001. SH2. 1 hit. PS50002. SH3. 2 hits. PS50081. ZF_DAG_PE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6WCA3_CIOIN

Accession

Primary (citable) accession number: F6WCA3

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	April 18, 2012
Last modified:	April 3, 2013
This is version 15 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)