Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

S-(hydroxymethyl)glutathione dehydrogenase

Gene

ADH5

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H.UniRule annotation

Cofactori

Zn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation, NADUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
S-(hydroxymethyl)glutathione dehydrogenaseUniRule annotation (EC:1.1.1.284UniRule annotation)
Gene namesi
Name:ADH5Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000013456.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 171ADH_NInterPro annotationAdd BLAST122
Domaini219 – 344ADH_zinc_NInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0022. Eukaryota.
COG1062. LUCA.
GeneTreeiENSGT00430000030800.
InParanoidiF6W0P4.
OMAiCIGNVNT.
OrthoDBiEOG091G08N3.
TreeFamiTF300429.

Family and domain databases

CDDicd08300. alcohol_DH_class_III. 1 hit.
InterProiView protein in InterPro
IPR014183. ADH_3.
IPR013149. ADH_C.
IPR013154. ADH_N.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like_sf.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR02818. adh_III_F_hyde. 1 hit.
PROSITEiView protein in PROSITE
PS00059. ADH_ZINC. 1 hit.

Sequencei

Sequence statusi: Complete.

F6W0P4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RAATPDVRPL RRPEPADMAN QVIKCKAAVA WEAGKPLFIE EIEVAPPKAH
60 70 80 90 100
EVRIKIIATA VCHTDAYTLS GADPEGCFPV ILGHEGAGIV ESVGEGVTKL
110 120 130 140 150
KAGDTVIPLY IPQCGECKFC LNPKTNLCQK IRVTQGKGLM PDGTSRFTCK
160 170 180 190 200
GKTILHYMGT STFSEYTVVA DISVAKIDPL APLDKVCLLG CGISTGYGAA
210 220 230 240 250
VNTAKVEPGS VCAVFGLGGV GLAVIMGCKV AGASRIIGVD INKDKFARAK
260 270 280 290 300
EFGATECVNP QDFSKPIQEV LIEMTDGGVD YSFECIGNVK VMRAALEACH
310 320 330 340 350
KGWGVSVVVG VAASGEEIAT RPFQLVTGRT WKGTAFGGWK SVESVPKLVS
360 370 380 390
EYMSKKIKVD EFVTHSLSFD EINEAFELMH SGKSIRTVVK I
Length:391
Mass (Da):41,628
Last modified:July 27, 2011 - v1
Checksum:i0A4F11546A05BBAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFV01015094 Genomic DNA. No translation available.
ACFV01015095 Genomic DNA. No translation available.
ACFV01015096 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCJAT00000014175; ENSCJAP00000013456; ENSCJAG00000007198.

Similar proteinsi

Entry informationi

Entry nameiF6W0P4_CALJA
AccessioniPrimary (citable) accession number: F6W0P4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported